diff --git a/CHANGELOG.md b/CHANGELOG.md
index b63232109b..5a24a589ff 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -16,10 +16,11 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 ### Added
 - `opentelemetry-instrumentation`: botocore: Add support for AWS Secrets Manager semantic convention attribute
   ([#3765](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3765))
+- `opentelemetry-instrumentation-dbapi`: Add support for `commenter_options` in `trace_integration` function to control SQLCommenter behavior
+  ([#3743](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3743))
 - Add `rstcheck` to pre-commit to stop introducing invalid RST
   ([#3777](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3777))
 
-
 ## Version 1.37.0/0.58b0 (2025-09-11)
 
 ### Fixed
diff --git a/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py b/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py
index a2d63c20e3..8e5752aefa 100644
--- a/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py
+++ b/instrumentation/opentelemetry-instrumentation-dbapi/src/opentelemetry/instrumentation/dbapi/__init__.py
@@ -79,6 +79,7 @@ def trace_integration(
     enable_commenter: bool = False,
     db_api_integration_factory: type[DatabaseApiIntegration] | None = None,
     enable_attribute_commenter: bool = False,
+    commenter_options: dict[str, Any] | None = None,
 ):
     """Integrate with DB API library.
     https://www.python.org/dev/peps/pep-0249/
@@ -97,6 +98,7 @@ def trace_integration(
         db_api_integration_factory: The `DatabaseApiIntegration` to use. If none is passed the
             default one is used.
         enable_attribute_commenter: Flag to enable/disable sqlcomment inclusion in `db.statement` span attribute. Only available if enable_commenter=True.
+        commenter_options: Configurations for tags to be appended at the sql query.
     """
     wrap_connect(
         __name__,
@@ -110,6 +112,7 @@ def trace_integration(
         enable_commenter=enable_commenter,
         db_api_integration_factory=db_api_integration_factory,
         enable_attribute_commenter=enable_attribute_commenter,
+        commenter_options=commenter_options,
     )
 
 
diff --git a/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py b/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py
index 9a7a4a7d12..223d07e2b7 100644
--- a/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py
+++ b/instrumentation/opentelemetry-instrumentation-dbapi/tests/test_dbapi_integration.py
@@ -259,6 +259,45 @@ def test_suppress_instrumentation(self):
         spans_list = self.memory_exporter.get_finished_spans()
         self.assertEqual(len(spans_list), 0)
 
+    def test_commenter_options_propagation(self):
+        db_integration = dbapi.DatabaseApiIntegration(
+            "instrumenting_module_test_name",
+            "testcomponent",
+            commenter_options={"opentelemetry_values": False},
+        )
+        mock_connection = db_integration.wrapped_connection(
+            mock_connect, {}, {}
+        )
+        cursor = mock_connection.cursor()
+        with self.assertRaises(Exception):
+            cursor.execute("SELECT 1", throw_exception=True)
+        spans_list = self.memory_exporter.get_finished_spans()
+        self.assertEqual(len(spans_list), 1)
+        span = spans_list[0]
+        self.assertEqual(span.attributes.get("db.system"), "testcomponent")
+        self.assertIn("opentelemetry_values", db_integration.commenter_options)
+        self.assertFalse(
+            db_integration.commenter_options["opentelemetry_values"]
+        )
+
+    @mock.patch("opentelemetry.instrumentation.dbapi.wrap_connect")
+    def test_trace_integration_passes_commenter_options(
+        self, mock_wrap_connect
+    ):
+        fake_connect_module = mock.Mock()
+        fake_options = {"opentelemetry_values": False, "foo": "bar"}
+        dbapi.trace_integration(
+            connect_module=fake_connect_module,
+            connect_method_name="connect",
+            database_system="testdb",
+            commenter_options=fake_options,
+        )
+        mock_wrap_connect.assert_called_once()
+        _, _, kwargs = mock_wrap_connect.mock_calls[0]
+
+        self.assertIn("commenter_options", kwargs)
+        self.assertEqual(kwargs["commenter_options"], fake_options)
+
     def test_executemany(self):
         db_integration = dbapi.DatabaseApiIntegration(
             "instrumenting_module_test_name", "testcomponent"