diff --git a/.github/workflows/benchmarks.yml b/.github/workflows/benchmarks.yml
index be9b44d8e2a..c31d01230a2 100644
--- a/.github/workflows/benchmarks.yml
+++ b/.github/workflows/benchmarks.yml
@@ -13,7 +13,8 @@ jobs:
     - name: Set up Python
       uses: actions/setup-python@v5
       with:
-        python-version: "3.12"
+        python-version: "3.13"
+        allow-prereleases: true
         architecture: 'x64'
     - name: Install tox
       run: pip install tox
diff --git a/docs/examples/error_handler/error_handler_0/pyproject.toml b/docs/examples/error_handler/error_handler_0/pyproject.toml
index fb8c889e61f..c48c86487b0 100644
--- a/docs/examples/error_handler/error_handler_0/pyproject.toml
+++ b/docs/examples/error_handler/error_handler_0/pyproject.toml
@@ -23,6 +23,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "opentelemetry-sdk ~= 1.3",
diff --git a/docs/examples/error_handler/error_handler_1/pyproject.toml b/docs/examples/error_handler/error_handler_1/pyproject.toml
index 5f72ff58480..f0d5499f0ed 100644
--- a/docs/examples/error_handler/error_handler_1/pyproject.toml
+++ b/docs/examples/error_handler/error_handler_1/pyproject.toml
@@ -23,6 +23,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "opentelemetry-sdk ~= 1.3",
diff --git a/exporter/opentelemetry-exporter-opencensus/pyproject.toml b/exporter/opentelemetry-exporter-opencensus/pyproject.toml
index 00a612aecc2..d6153468445 100644
--- a/exporter/opentelemetry-exporter-opencensus/pyproject.toml
+++ b/exporter/opentelemetry-exporter-opencensus/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/exporter/opentelemetry-exporter-otlp-proto-common/pyproject.toml b/exporter/opentelemetry-exporter-otlp-proto-common/pyproject.toml
index 4453eb9eb86..318569d6d67 100644
--- a/exporter/opentelemetry-exporter-otlp-proto-common/pyproject.toml
+++ b/exporter/opentelemetry-exporter-otlp-proto-common/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "opentelemetry-proto == 1.28.0.dev",
diff --git a/exporter/opentelemetry-exporter-otlp-proto-grpc/pyproject.toml b/exporter/opentelemetry-exporter-otlp-proto-grpc/pyproject.toml
index f2ed898e7dc..24fd65bee0a 100644
--- a/exporter/opentelemetry-exporter-otlp-proto-grpc/pyproject.toml
+++ b/exporter/opentelemetry-exporter-otlp-proto-grpc/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "Deprecated >= 1.2.6",
diff --git a/exporter/opentelemetry-exporter-otlp-proto-http/pyproject.toml b/exporter/opentelemetry-exporter-otlp-proto-http/pyproject.toml
index 77f6063f467..c8d42cffd32 100644
--- a/exporter/opentelemetry-exporter-otlp-proto-http/pyproject.toml
+++ b/exporter/opentelemetry-exporter-otlp-proto-http/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "Deprecated >= 1.2.6",
diff --git a/exporter/opentelemetry-exporter-otlp/pyproject.toml b/exporter/opentelemetry-exporter-otlp/pyproject.toml
index 7566929537a..f6d50f7cb0e 100644
--- a/exporter/opentelemetry-exporter-otlp/pyproject.toml
+++ b/exporter/opentelemetry-exporter-otlp/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/exporter/opentelemetry-exporter-prometheus/pyproject.toml b/exporter/opentelemetry-exporter-prometheus/pyproject.toml
index e3b09d18267..abf031d8b96 100644
--- a/exporter/opentelemetry-exporter-prometheus/pyproject.toml
+++ b/exporter/opentelemetry-exporter-prometheus/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "opentelemetry-api ~= 1.12",
diff --git a/exporter/opentelemetry-exporter-zipkin-json/pyproject.toml b/exporter/opentelemetry-exporter-zipkin-json/pyproject.toml
index 70b4f72ea48..756913483f0 100644
--- a/exporter/opentelemetry-exporter-zipkin-json/pyproject.toml
+++ b/exporter/opentelemetry-exporter-zipkin-json/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/exporter/opentelemetry-exporter-zipkin-proto-http/pyproject.toml b/exporter/opentelemetry-exporter-zipkin-proto-http/pyproject.toml
index 71018d2263c..36e937b0611 100644
--- a/exporter/opentelemetry-exporter-zipkin-proto-http/pyproject.toml
+++ b/exporter/opentelemetry-exporter-zipkin-proto-http/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/exporter/opentelemetry-exporter-zipkin/pyproject.toml b/exporter/opentelemetry-exporter-zipkin/pyproject.toml
index b9e51b04757..cb367df4fff 100644
--- a/exporter/opentelemetry-exporter-zipkin/pyproject.toml
+++ b/exporter/opentelemetry-exporter-zipkin/pyproject.toml
@@ -25,6 +25,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/opentelemetry-api/pyproject.toml b/opentelemetry-api/pyproject.toml
index 36b5fb06a58..6839f8287ff 100644
--- a/opentelemetry-api/pyproject.toml
+++ b/opentelemetry-api/pyproject.toml
@@ -23,6 +23,7 @@ classifiers = [
     "Programming Language :: Python :: 3.10",
     "Programming Language :: Python :: 3.11",
     "Programming Language :: Python :: 3.12",
+    "Programming Language :: Python :: 3.13",
     "Typing :: Typed",
 ]
 dependencies = [
diff --git a/opentelemetry-proto/pyproject.toml b/opentelemetry-proto/pyproject.toml
index 505a88f4d5c..8e5063af068 100644
--- a/opentelemetry-proto/pyproject.toml
+++ b/opentelemetry-proto/pyproject.toml
@@ -24,6 +24,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "protobuf>=3.19, < 5.0",
diff --git a/propagator/opentelemetry-propagator-b3/pyproject.toml b/propagator/opentelemetry-propagator-b3/pyproject.toml
index f8abf0bc3ce..23694ce167e 100644
--- a/propagator/opentelemetry-propagator-b3/pyproject.toml
+++ b/propagator/opentelemetry-propagator-b3/pyproject.toml
@@ -24,6 +24,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/propagator/opentelemetry-propagator-jaeger/pyproject.toml b/propagator/opentelemetry-propagator-jaeger/pyproject.toml
index 9bdf0513b02..f96a79ea7ce 100644
--- a/propagator/opentelemetry-propagator-jaeger/pyproject.toml
+++ b/propagator/opentelemetry-propagator-jaeger/pyproject.toml
@@ -24,6 +24,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/shim/opentelemetry-opencensus-shim/pyproject.toml b/shim/opentelemetry-opencensus-shim/pyproject.toml
index b4fdfb6e9f8..a1089242cb0 100644
--- a/shim/opentelemetry-opencensus-shim/pyproject.toml
+++ b/shim/opentelemetry-opencensus-shim/pyproject.toml
@@ -24,6 +24,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/shim/opentelemetry-opentracing-shim/pyproject.toml b/shim/opentelemetry-opentracing-shim/pyproject.toml
index 0345178f903..4743cc203eb 100644
--- a/shim/opentelemetry-opentracing-shim/pyproject.toml
+++ b/shim/opentelemetry-opentracing-shim/pyproject.toml
@@ -24,6 +24,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
   "Typing :: Typed",
 ]
 dependencies = [
diff --git a/tests/opentelemetry-test-utils/pyproject.toml b/tests/opentelemetry-test-utils/pyproject.toml
index 3512307a2f9..1ab95abc3e1 100644
--- a/tests/opentelemetry-test-utils/pyproject.toml
+++ b/tests/opentelemetry-test-utils/pyproject.toml
@@ -24,6 +24,7 @@ classifiers = [
   "Programming Language :: Python :: 3.10",
   "Programming Language :: Python :: 3.11",
   "Programming Language :: Python :: 3.12",
+  "Programming Language :: Python :: 3.13",
 ]
 dependencies = [
   "asgiref ~= 3.0",
diff --git a/tox.ini b/tox.ini
index 23f5947c4bd..5e56710d79a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -6,7 +6,7 @@ envlist =
     ; Environments are organized by individual package, allowing
     ; for specifying supported Python versions per package.
 
-    py3{8,9,10,11,12}-test-opentelemetry-api
+    py3{8,9,10,11,12,13}-test-opentelemetry-api
     pypy3-test-opentelemetry-api
     lint-opentelemetry-api
 
@@ -14,31 +14,31 @@ envlist =
     ; below mean these dependencies are being used:
     ; 0: protobuf==3.20.3
     ; 1: protobuf==4.25.3
-    py3{8,9,10,11,12}-test-opentelemetry-proto-{0,1}
+    py3{8,9,10,11,12,13}-test-opentelemetry-proto-{0,1}
     pypy3-test-opentelemetry-proto-{0,1}
     lint-opentelemetry-proto
 
-    py3{8,9,10,11,12}-test-opentelemetry-sdk
+    py3{8,9,10,11,12,13}-test-opentelemetry-sdk
     pypy3-test-opentelemetry-sdk
     lint-opentelemetry-sdk
     benchmark-opentelemetry-sdk
 
-    py3{8,9,10,11,12}-test-opentelemetry-semantic-conventions
+    py3{8,9,10,11,12,13}-test-opentelemetry-semantic-conventions
     pypy3-test-opentelemetry-semantic-conventions
     lint-opentelemetry-semantic-conventions
 
-    py3{8,9,10,11,12}-test-opentelemetry-getting-started
+    py3{8,9,10,11,12,13}-test-opentelemetry-getting-started
     lint-opentelemetry-getting-started
 
-    py3{8,9,10,11,12}-test-opentelemetry-opentracing-shim
+    py3{8,9,10,11,12,13}-test-opentelemetry-opentracing-shim
     pypy3-test-opentelemetry-opentracing-shim
     lint-opentelemetry-opentracing-shim
 
-    py3{8,9,10,11,12}-test-opentelemetry-opencensus-shim
+    py3{8,9,10,11,12,13}-test-opentelemetry-opencensus-shim
     ; opencensus-shim intentionally excluded from pypy3 (grpcio install fails)
     lint-opentelemetry-opencensus-shim
 
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-opencensus
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-opencensus
     ; exporter-opencensus intentionally excluded from pypy3
     lint-opentelemetry-exporter-opencensus
 
@@ -46,12 +46,12 @@ envlist =
     ; below mean these dependencies are being used:
     ; 0: protobuf==3.20.3
     ; 1: protobuf==4.25.3
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-otlp-proto-common-{0,1}
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-otlp-proto-common-{0,1}
     pypy3-test-opentelemetry-exporter-otlp-proto-common-{0,1}
     lint-opentelemetry-exporter-otlp-proto-common
 
     ; opentelemetry-exporter-otlp
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-otlp-combined
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-otlp-combined
     ; intentionally excluded from pypy3
     lint-opentelemetry-exporter-otlp-combined
 
@@ -59,7 +59,7 @@ envlist =
     ; below mean these dependencies are being used:
     ; 0: protobuf==3.20.3
     ; 1: protobuf==4.25.3
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-otlp-proto-grpc-{0,1}
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-otlp-proto-grpc-{0,1}
     ; intentionally excluded from pypy3
     lint-opentelemetry-exporter-otlp-proto-grpc
     benchmark-opentelemetry-exporter-otlp-proto-grpc
@@ -68,37 +68,37 @@ envlist =
     ; below mean these dependencies are being used:
     ; 0: protobuf==3.20.3
     ; 1: protobuf==4.25.3
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-otlp-proto-http-{0,1}
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-otlp-proto-http-{0,1}
     pypy3-test-opentelemetry-exporter-otlp-proto-http-{0,1}
     lint-opentelemetry-exporter-otlp-proto-http
 
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-prometheus
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-prometheus
     pypy3-test-opentelemetry-exporter-prometheus
     lint-opentelemetry-exporter-prometheus
 
     ; opentelemetry-exporter-zipkin
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-zipkin-combined
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-zipkin-combined
     pypy3-test-opentelemetry-exporter-zipkin-combined
     lint-opentelemetry-exporter-zipkin-combined
 
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-zipkin-proto-http
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-zipkin-proto-http
     pypy3-test-opentelemetry-exporter-zipkin-proto-http
     lint-opentelemetry-exporter-zipkin-proto-http
 
-    py3{8,9,10,11,12}-test-opentelemetry-exporter-zipkin-json
+    py3{8,9,10,11,12,13}-test-opentelemetry-exporter-zipkin-json
     pypy3-test-opentelemetry-exporter-zipkin-json
     lint-opentelemetry-exporter-zipkin-json
 
-    py3{8,9,10,11,12}-test-opentelemetry-propagator-b3
+    py3{8,9,10,11,12,13}-test-opentelemetry-propagator-b3
     pypy3-test-opentelemetry-propagator-b3
     lint-opentelemetry-propagator-b3
     benchmark-opentelemetry-propagator-b3
 
-    py3{8,9,10,11,12}-test-opentelemetry-propagator-jaeger
+    py3{8,9,10,11,12,13}-test-opentelemetry-propagator-jaeger
     pypy3-test-opentelemetry-propagator-jaeger
     lint-opentelemetry-propagator-jaeger
 
-    py3{8,9,10,11,12}-test-opentelemetry-test-utils
+    py3{8,9,10,11,12,13}-test-opentelemetry-test-utils
     pypy3-test-opentelemetry-test-utils
     lint-opentelemetry-test-utils