diff --git a/.changeset/young-birds-hammer.md b/.changeset/young-birds-hammer.md
new file mode 100644
index 00000000..71bc48b3
--- /dev/null
+++ b/.changeset/young-birds-hammer.md
@@ -0,0 +1,6 @@
+---
+'@openai/agents-openai': patch
+'@openai/agents-core': patch
+---
+
+Fix #216 Publicly accessible PDF file URL is not yet supported in the input_file content data
diff --git a/examples/basic/package.json b/examples/basic/package.json
index ca6b75bd..91a40531 100644
--- a/examples/basic/package.json
+++ b/examples/basic/package.json
@@ -17,6 +17,7 @@
     "start:previous-response-id": "tsx previous-response-id.ts",
     "start:prompt": "tsx prompt-id.ts",
     "start:remote-image": "tsx remote-image.ts",
+    "start:remote-pdf": "tsx remote-pdf.ts",
     "start:stream-items": "tsx stream-items.ts",
     "start:stream-text": "tsx stream-text.ts",
     "start:json-schema-output-type": "tsx json-schema-output-type.ts",
diff --git a/examples/basic/remote-image.ts b/examples/basic/remote-image.ts
index b43023b3..52cffc64 100644
--- a/examples/basic/remote-image.ts
+++ b/examples/basic/remote-image.ts
@@ -1,6 +1,6 @@
 import { Agent, run } from '@openai/agents';
 
-const URL =
+const url =
   'https://upload.wikimedia.org/wikipedia/commons/0/0c/GoldenGateBridge-001.jpg';
 
 async function main() {
@@ -15,7 +15,7 @@ async function main() {
       content: [
         {
           type: 'input_image',
-          image: URL,
+          image: url,
           providerData: {
             detail: 'auto',
           },
diff --git a/examples/basic/remote-pdf.ts b/examples/basic/remote-pdf.ts
new file mode 100644
index 00000000..7ff38acc
--- /dev/null
+++ b/examples/basic/remote-pdf.ts
@@ -0,0 +1,27 @@
+import { Agent, run } from '@openai/agents';
+
+const url = 'https://www.berkshirehathaway.com/letters/2024ltr.pdf';
+
+async function main() {
+  const agent = new Agent({
+    name: 'Assistant',
+    instructions: 'You are a helpful assistant.',
+  });
+
+  const result = await run(agent, [
+    {
+      role: 'user',
+      content: [{ type: 'input_file', file: url }],
+    },
+    {
+      role: 'user',
+      content: 'Can you summarize the letter?',
+    },
+  ]);
+
+  console.log(result.finalOutput);
+}
+
+if (require.main === module) {
+  main().catch(console.error);
+}
diff --git a/packages/agents-core/src/types/protocol.ts b/packages/agents-core/src/types/protocol.ts
index 577a8703..95a5a98c 100644
--- a/packages/agents-core/src/types/protocol.ts
+++ b/packages/agents-core/src/types/protocol.ts
@@ -91,9 +91,17 @@ export const InputFile = SharedBase.extend({
    */
   file: z
     .string()
+    .describe(
+      'Either base64 encoded file data or a publicly accessible file URL',
+    )
     .or(
       z.object({
-        id: z.string(),
+        id: z.string().describe('OpenAI file ID'),
+      }),
+    )
+    .or(
+      z.object({
+        url: z.string().describe('Publicly accessible PDF file URL'),
       }),
     )
     .describe('Contents of the file or an object with a file ID.'),
diff --git a/packages/agents-openai/src/openaiResponsesModel.ts b/packages/agents-openai/src/openaiResponsesModel.ts
index 3172b4f0..73c7bb87 100644
--- a/packages/agents-openai/src/openaiResponsesModel.ts
+++ b/packages/agents-openai/src/openaiResponsesModel.ts
@@ -266,9 +266,19 @@ function getInputMessageContent(
       type: 'input_file',
     };
     if (typeof entry.file === 'string') {
-      fileEntry.file_data = entry.file;
-    } else {
+      if (entry.file.startsWith('data:')) {
+        fileEntry.file_data = entry.file;
+      } else if (entry.file.startsWith('https://')) {
+        fileEntry.file_url = entry.file;
+      } else {
+        throw new UserError(
+          `Unsupported string data for file input. If you're trying to pass an uploaded file's ID, use an object with the ID property instead.`,
+        );
+      }
+    } else if ('id' in entry.file) {
       fileEntry.file_id = entry.file.id;
+    } else if ('url' in entry.file) {
+      fileEntry.file_url = entry.file.url;
     }
     return {
       ...fileEntry,