diff --git a/Dockerfile.ubi b/Dockerfile.ubi
index eaa046c371a7..f50637dc0392 100644
--- a/Dockerfile.ubi
+++ b/Dockerfile.ubi
@@ -5,6 +5,7 @@ ARG PYTHON_VERSION=3.12
 ARG TORCH_CUDA_ARCH_LIST="7.0 7.5 8.0 8.6 8.9 9.0+PTX"
 ARG vllm_fa_cmake_gpu_arches='80-real;90-real'
 
+
 ## Base Layer ##################################################################
 FROM registry.access.redhat.com/ubi9/ubi-minimal:${BASE_UBI_IMAGE_TAG} as base
 ARG PYTHON_VERSION
@@ -50,12 +51,22 @@ ENV CUDA_HOME="/usr/local/cuda" \
     PATH="${CUDA_HOME}/bin:${PATH}" \
     LD_LIBRARY_PATH="${CUDA_HOME}/lib64:${CUDA_HOME}/extras/CUPTI/lib64:${LD_LIBRARY_PATH}"
 
+
 ## Python cuda base #################################################################
 FROM cuda-base AS python-cuda-base
 
 ENV VIRTUAL_ENV=/opt/vllm
 ENV PATH="$VIRTUAL_ENV/bin:$PATH"
 
+# install numactl and common dependencies for fastsafetensors
+RUN microdnf install autoconf automake libtool make rpm-build -y && \
+    microdnf download --source numactl.src && \
+    NUMACTL_V=$(rpm -qp --qf "%{VERSION}-%{RELEASE}\n" numactl-*.rpm | sort -V | tail -n 1) && \
+    rpm -i numactl-${NUMACTL_V}.src.rpm && \
+    rpmbuild -ba /root/rpmbuild/SPECS/numactl.spec && \
+    rpm -i /root/rpmbuild/RPMS/x86_64/{numactl-libs-${NUMACTL_V}.x86_64.rpm,numactl-${NUMACTL_V}.x86_64.rpm,numactl-devel-${NUMACTL_V}.x86_64.rpm} && \
+    microdnf clean all
+
 # install cuda and common dependencies
 RUN --mount=type=cache,target=/root/.cache/pip \
     --mount=type=cache,target=/root/.cache/uv \
@@ -80,6 +91,7 @@ RUN --mount=type=cache,target=/root/.cache/pip \
         -r requirements-cuda.txt \
         -r requirements-dev.txt
 
+
 ## Builder #####################################################################
 FROM dev AS build
 
@@ -122,6 +134,7 @@ RUN --mount=type=cache,target=/root/.cache/ccache \
         CMAKE_BUILD_TYPE=Release \
         python3 setup.py bdist_wheel --dist-dir=dist
 
+
 #################### libsodium Build IMAGE ####################
 FROM base as libsodium-builder
 
@@ -139,6 +152,7 @@ RUN curl -LO https://github.com/jedisct1/libsodium/releases/download/${LIBSODIUM
 RUN CFLAGS="-O3 -Wall -Werror=format-security -Wno-unused-function -Wp,-D_GLIBCXX_ASSERTIONS -fstack-protector-strong -fstack-clash-protection -fcf-protection"\
     ./configure --prefix="/usr/" && make -j $MAX_JOBS && make check
 
+
 ## Release #####################################################################
 FROM python-install AS vllm-openai
 ARG PYTHON_VERSION
@@ -152,6 +166,7 @@ ENV PATH=$VIRTUAL_ENV/bin:$PATH
 ENV LD_LIBRARY_PATH="${VIRTUAL_ENV}/lib/python${PYTHON_VERSION}/site-packages/nvidia/cuda_nvrtc/lib:${LD_LIBRARY_PATH}"
 ENV LD_LIBRARY_PATH="${VIRTUAL_ENV}/lib/python${PYTHON_VERSION}/site-packages/nvidia/cuda_runtime/lib:${LD_LIBRARY_PATH}"
 ENV LD_LIBRARY_PATH="${VIRTUAL_ENV}/lib/python${PYTHON_VERSION}/site-packages/nvidia/nvtx/lib:${LD_LIBRARY_PATH}"
+ENV LD_LIBRARY_PATH="${VIRTUAL_ENV}/lib/python${PYTHON_VERSION}/site-packages/nvidia/cufile/lib:${LD_LIBRARY_PATH}"
 
 # Triton needs a CC compiler
 RUN microdnf install -y gcc \
@@ -202,14 +217,21 @@ WORKDIR /home/vllm
 ENTRYPOINT ["python3", "-m", "vllm.entrypoints.openai.api_server"]
 
 
+## Last image ##################################################################
 FROM vllm-openai as vllm-grpc-adapter
 
 USER root
 
+# Installing numactl and numactl-libs for fastsafetensors
+RUN --mount=type=bind,from=python-cuda-base,src=/root/rpmbuild/RPMS/x86_64,target=/workspace/RPMS \
+    NUMACTL_V=$(rpm -qp --qf "%{VERSION}-%{RELEASE}\n" /workspace/RPMS/numactl-*.rpm | sort -V | tail -n 1) && \
+    rpm -i /workspace/RPMS/numactl-${NUMACTL_V}.x86_64.rpm /workspace/RPMS/numactl-libs-${NUMACTL_V}.x86_64.rpm
+
+# Ensure correct vLLM version, vllm-tgis-adapter and cufile for fastsafetensors
 RUN --mount=type=cache,target=/root/.cache/pip \
     --mount=type=cache,target=/root/.cache/uv \
     --mount=type=bind,from=build,src=/workspace/dist,target=/workspace/dist \
-    HOME=/root uv pip install "$(echo /workspace/dist/*.whl)[tensorizer]" vllm-tgis-adapter==0.6.0
+    HOME=/root uv pip install "$(echo /workspace/dist/*.whl)[tensorizer]" vllm-tgis-adapter==0.6.0 nvidia-cufile-cu12
 
 ENV GRPC_PORT=8033 \
     PORT=8000 \
diff --git a/docs/source/serving/weights_loading_with_fastsafetensor.rst b/docs/source/serving/weights_loading_with_fastsafetensor.rst
new file mode 100644
index 000000000000..2678ae38a15e
--- /dev/null
+++ b/docs/source/serving/weights_loading_with_fastsafetensor.rst
@@ -0,0 +1,5 @@
+Loading Model weights with fastsafetensors
+===================================================================
+
+Using fastsafetensor library enables loading model weights to GPU memory by leveraging GPU direct storage. See https://github.com/foundation-model-stack/fastsafetensors for more details.
+For enabling this feature, set the environment variable ``USE_FASTSAFETENSOR`` to ``true``
\ No newline at end of file
diff --git a/requirements-cuda.txt b/requirements-cuda.txt
index 8002fbd8ee5b..f793b822423f 100644
--- a/requirements-cuda.txt
+++ b/requirements-cuda.txt
@@ -8,3 +8,4 @@ torch == 2.5.1
 # These must be updated alongside torch
 torchvision == 0.20.1 # Required for phi3v processor. See https://github.com/pytorch/vision?tab=readme-ov-file#installation for corresponding version
 xformers == 0.0.28.post3; platform_system == 'Linux' and platform_machine == 'x86_64'  # Requires PyTorch 2.5.1
+fastsafetensors # Required for model loading via gpu direct storage
\ No newline at end of file
diff --git a/vllm/model_executor/model_loader/loader.py b/vllm/model_executor/model_loader/loader.py
index f2d9293b31a8..791ee01cd204 100644
--- a/vllm/model_executor/model_loader/loader.py
+++ b/vllm/model_executor/model_loader/loader.py
@@ -42,9 +42,10 @@
                                                     set_default_torch_dtype)
 from vllm.model_executor.model_loader.weight_utils import (
     download_safetensors_index_file_from_hf, download_weights_from_hf,
-    filter_duplicate_safetensors_files, filter_files_not_needed_for_inference,
-    get_gguf_extra_tensor_names, gguf_quant_weights_iterator,
-    initialize_dummy_weights, np_cache_weights_iterator, pt_weights_iterator,
+    fastsafetensors_weights_iterator, filter_duplicate_safetensors_files,
+    filter_files_not_needed_for_inference, get_gguf_extra_tensor_names,
+    gguf_quant_weights_iterator, initialize_dummy_weights,
+    np_cache_weights_iterator, pt_weights_iterator,
     runai_safetensors_weights_iterator, safetensors_weights_iterator)
 from vllm.model_executor.utils import set_weight_attrs
 from vllm.platforms import current_platform
@@ -307,7 +308,15 @@ def _get_weights_iterator(
                 hf_weights_files,
             )
         elif use_safetensors:
-            weights_iterator = safetensors_weights_iterator(hf_weights_files)
+            use_fastsafe_tensor = os.getenv('USE_FASTSAFETENSOR',
+                                            'False').lower() == 'true'
+            if use_fastsafe_tensor:
+                logger.info("Using fastsafetensor for loading weights")
+                weights_iterator = fastsafetensors_weights_iterator(
+                    hf_weights_files)
+            else:
+                weights_iterator = safetensors_weights_iterator(
+                    hf_weights_files)
         else:
             weights_iterator = pt_weights_iterator(hf_weights_files)
 
diff --git a/vllm/model_executor/model_loader/weight_utils.py b/vllm/model_executor/model_loader/weight_utils.py
index 8aa0c98df70d..7002df2d99a2 100644
--- a/vllm/model_executor/model_loader/weight_utils.py
+++ b/vllm/model_executor/model_loader/weight_utils.py
@@ -14,6 +14,7 @@
 import huggingface_hub.constants
 import numpy as np
 import torch
+from fastsafetensors import SafeTensorsFileLoader, SingleGroup
 from huggingface_hub import HfFileSystem, hf_hub_download, snapshot_download
 from safetensors.torch import load_file, safe_open, save_file
 from tqdm.auto import tqdm
@@ -418,6 +419,37 @@ def safetensors_weights_iterator(
                 yield name, param
 
 
+def fastsafetensors_weights_iterator(
+    hf_weights_files: List[str]
+) -> Generator[Tuple[str, torch.Tensor], None, None]:
+    """Iterate over the weights in the model safetensor files 
+    using fastsafetensor library."""
+    pg = SingleGroup()
+    if torch.distributed.is_initialized():
+        pg = torch.distributed.group.WORLD
+
+    device = torch.device(f'cuda:{pg.rank()}')
+    weight_files_sub_lists = [
+        hf_weights_files[i:i + pg.size()]
+        for i in range(0, len(hf_weights_files), pg.size())
+    ]
+
+    for f_list in weight_files_sub_lists:
+        # nogds=True DISABLE the NVIDIA GDS support for fastsafetensors
+        loader = SafeTensorsFileLoader(pg, device,
+                                       nogds=True,
+                                       debug_log=False)
+        rank_file_map = {i: [f] for i, f in enumerate(f_list)}
+        loader.add_filenames(rank_file_map)
+        fb = loader.copy_files_to_device()
+        keys = list(fb.key_to_rank_lidx.keys())
+        for k in keys:
+            t = fb.get_tensor(k)
+            yield k, t
+        fb.close()
+        loader.close()
+
+
 def runai_safetensors_weights_iterator(
     hf_weights_files: List[str]
 ) -> Generator[Tuple[str, torch.Tensor], None, None]: