diff --git a/cmd/machine-api-tests-ext/main.go b/cmd/machine-api-tests-ext/main.go
index 7f5b625b6..5f7eec5ba 100644
--- a/cmd/machine-api-tests-ext/main.go
+++ b/cmd/machine-api-tests-ext/main.go
@@ -15,6 +15,7 @@ import (
 	"k8s.io/component-base/logs"
 
 	// If using ginkgo, import your tests here
+	_ "github.com/openshift/machine-api-operator/test/e2e/nutanix"
 	_ "github.com/openshift/machine-api-operator/test/e2e/vsphere"
 )
 
diff --git a/cmd/machine-api-tests-ext/provider.go b/cmd/machine-api-tests-ext/provider.go
index 7fc96febf..1d7c8753e 100644
--- a/cmd/machine-api-tests-ext/provider.go
+++ b/cmd/machine-api-tests-ext/provider.go
@@ -28,11 +28,23 @@ import (
 	_ "k8s.io/kubernetes/test/e2e/lifecycle"
 )
 
+func newProvider() (framework.ProviderInterface, error) {
+	return &Provider{}, nil
+}
+
+// Structure to handle nutanix for e2e testing
+type Provider struct {
+	framework.NullProvider
+}
+
 // copied directly from github.com/openshift/kubernetes/openshift-hack/cmd/k8s-tests-ext/provider.go
 // I attempted to use the clusterdiscovery.InitializeTestFramework in origin but it has too many additional parameters
 // that as an test-ext, I felt we shouldn't have to load all that.  Hopefully origin's test-ext frameworks gets enhanced
 // to have a simple way to initialize all this w/o having to copy/pasta like the openshift/kubernetes project did.
 func initializeTestFramework(provider string) error {
+	if provider == `{"type":"nutanix"}` {
+		framework.RegisterProvider("nutanix", newProvider)
+	}
 	providerInfo := &ClusterConfiguration{}
 	if err := json.Unmarshal([]byte(provider), &providerInfo); err != nil {
 		return fmt.Errorf("provider must be a JSON object with the 'type' key at a minimum: %v", err)
diff --git a/pkg/webhooks/machine_webhook.go b/pkg/webhooks/machine_webhook.go
index 36f106248..c3eca08ac 100644
--- a/pkg/webhooks/machine_webhook.go
+++ b/pkg/webhooks/machine_webhook.go
@@ -1941,15 +1941,16 @@ func validateNutanixDataDisks(disks []machinev1.NutanixVMDisk) (fldErrs []*field
 
 func validateNutanixResourceIdentifier(resource string, identifier machinev1.NutanixResourceIdentifier) *field.Error {
 	parentPath := field.NewPath("providerSpec")
-	if identifier.Type == machinev1.NutanixIdentifierName {
+	switch identifier.Type {
+	case machinev1.NutanixIdentifierName:
 		if identifier.Name == nil || *identifier.Name == "" {
 			return field.Required(parentPath.Child(resource).Child("name"), fmt.Sprintf("%s name must be provided", resource))
 		}
-	} else if identifier.Type == machinev1.NutanixIdentifierUUID {
+	case machinev1.NutanixIdentifierUUID:
 		if identifier.UUID == nil || *identifier.UUID == "" {
 			return field.Required(parentPath.Child(resource).Child("uuid"), fmt.Sprintf("%s UUID must be provided", resource))
 		}
-	} else {
+	default:
 		return field.Invalid(parentPath.Child(resource).Child("type"), identifier.Type, fmt.Sprintf("%s type must be one of %s or %s", resource, machinev1.NutanixIdentifierName, machinev1.NutanixIdentifierUUID))
 	}
 
diff --git a/test/e2e/nutanix/multi-subnet.go b/test/e2e/nutanix/multi-subnet.go
new file mode 100644
index 000000000..c9e4d6347
--- /dev/null
+++ b/test/e2e/nutanix/multi-subnet.go
@@ -0,0 +1,221 @@
+package nutanix
+
+import (
+	"context"
+	_ "embed"
+	"encoding/json"
+	"slices"
+	"sort"
+
+	. "github.com/onsi/ginkgo/v2"
+	. "github.com/onsi/gomega"
+	configv1 "github.com/openshift/api/config/v1"
+	machinev1beta1 "github.com/openshift/api/machine/v1beta1"
+	configclient "github.com/openshift/client-go/config/clientset/versioned/typed/config/v1"
+	machinesetclient "github.com/openshift/client-go/machine/clientset/versioned/typed/machine/v1beta1"
+
+	e2eutil "github.com/openshift/machine-api-operator/test/e2e"
+	corev1 "k8s.io/api/core/v1"
+	metav1 "k8s.io/apimachinery/pkg/apis/meta/v1"
+
+	"k8s.io/client-go/kubernetes"
+	"k8s.io/client-go/rest"
+	e2e "k8s.io/kubernetes/test/e2e/framework"
+)
+
+func failIfMachinesNotHaveMultipleNetwork(machines *machinev1beta1.MachineList) {
+	By("checking if machines have multiple network addresses")
+	for _, machines := range machines.Items {
+		count := 0
+		for _, address := range machines.Status.Addresses {
+			if address.Type == "Internal" {
+				count = count + 1
+			}
+		}
+		Expect(count).To(BeNumerically(">", 1))
+	}
+}
+
+func failIfNodeNotInMachineNetwork(nodes *corev1.NodeList) {
+	By("checking if nodes are in the machine network")
+
+	for _, node := range nodes.Items {
+		for _, address := range node.Status.Addresses {
+			if address.Type != "InternalIP" && address.Type != "ExternalIP" {
+				continue
+			}
+			cidrFound := false
+			cidrsJSON := node.Annotations["k8s.ovn.org/host-cidrs"]
+			var cidrs []string
+			if err := json.Unmarshal([]byte(cidrsJSON), &cidrs); err != nil {
+				Expect(err).NotTo(HaveOccurred())
+			}
+			for _, cidr := range cidrs {
+				inRange, err := isIpInCidrRange(address.Address, cidr)
+				Expect(err).NotTo(HaveOccurred())
+
+				if inRange {
+					cidrFound = true
+					break
+				}
+			}
+			Expect(cidrFound).To(BeTrue(), "machine IP must be in one of the machine network CIDR ranges")
+		}
+	}
+}
+
+func failIfMachinesDoesNotContainAllSubnet(machines *machinev1beta1.MachineList, machineNetworks []configv1.NutanixFailureDomain) {
+	By("checking node address against Nutanix failure domains")
+	failureDomainSubnets := make(map[string][]string)
+	for _, domain := range machineNetworks {
+		for _, subnet := range domain.Subnets {
+			failureDomainSubnets[domain.Name] = append(failureDomainSubnets[domain.Name], *subnet.UUID)
+		}
+		sort.Strings(failureDomainSubnets[domain.Name])
+		failureDomainMachines, err := getMachinesInFailureDomain(machines, domain.Name)
+		Expect(err).ToNot(HaveOccurred())
+		for _, machine := range failureDomainMachines {
+			machineSubnets := []string{}
+			spec, err := ProviderSpecFromRawExtension(machine.Spec.ProviderSpec.Value)
+			Expect(err).NotTo(HaveOccurred())
+			for _, subnet := range spec.Subnets {
+				machineSubnets = append(machineSubnets, *subnet.UUID)
+			}
+			sort.Strings(machineSubnets)
+			Expect(slices.Equal(machineSubnets, failureDomainSubnets[domain.Name])).To(BeTrue())
+		}
+	}
+}
+
+func failIfMachinesIfDuplicateIP(machines *machinev1beta1.MachineList) {
+	seen := make(map[string]bool)
+	for _, machine := range machines.Items {
+		for _, addr := range machine.Status.Addresses {
+			if addr.Type == "InternalIP" || addr.Type == "ExternalIP" {
+				Expect(seen[addr.Address]).To(BeFalse(), "Duplicate IP address found: "+addr.Address)
+				seen[addr.Address] = true
+			}
+		}
+	}
+}
+
+var _ = Describe("[sig-cluster-lifecycle][OCPFeatureGate:NutanixMultiSubnets][platform:nutanix] Managed cluster should support multi-subnet networking", Label("Conformance"), Label("Parallel"), func() {
+	defer GinkgoRecover()
+	ctx := context.Background()
+
+	var (
+		cfg *rest.Config
+		c   *kubernetes.Clientset
+		cc  *configclient.ConfigV1Client
+
+		mc              *machinesetclient.MachineV1beta1Client
+		err             error
+		machineNetworks []configv1.NutanixFailureDomain
+		infra           *configv1.Infrastructure
+		nodes           *corev1.NodeList
+		machines        *machinev1beta1.MachineList
+	)
+
+	BeforeEach(func() {
+		cfg, err = e2e.LoadConfig()
+		Expect(err).NotTo(HaveOccurred())
+		c, err = e2e.LoadClientset()
+		Expect(err).NotTo(HaveOccurred())
+		mc, err = machinesetclient.NewForConfig(cfg)
+		Expect(err).NotTo(HaveOccurred())
+		cc, err = configclient.NewForConfig(cfg)
+		Expect(err).NotTo(HaveOccurred())
+		infra, err = cc.Infrastructures().Get(ctx, "cluster", metav1.GetOptions{})
+		Expect(err).NotTo(HaveOccurred())
+
+		Expect(len(infra.Spec.PlatformSpec.Nutanix.FailureDomains)).ShouldNot(Equal(0))
+
+		machineNetworks = append(machineNetworks, infra.Spec.PlatformSpec.Nutanix.FailureDomains...)
+		Expect(len(machineNetworks)).ShouldNot(Equal(0))
+
+		// err = fmt.Errorf("FD %s: PE=%s, Subnets=%v", machineNetworks[0].Name, *machineNetworks[0].Cluster.UUID, *machineNetworks[0].Subnets[0].UUID)
+		//Expect(err).NotTo(HaveOccurred())
+
+		nodes, err = c.CoreV1().Nodes().List(ctx, metav1.ListOptions{})
+		Expect(err).NotTo(HaveOccurred())
+
+		machines, err = mc.Machines("openshift-machine-api").List(ctx, metav1.ListOptions{})
+		Expect(err).NotTo(HaveOccurred())
+
+		if len(machines.Items) == 0 {
+			Skip("skipping due to lack of machines / IPI cluster")
+		}
+	})
+
+	It("machines should have multiple Internal Address [apigroup:machine.openshift.io][Suite:openshift/conformance/parallel]", func() {
+		failIfMachinesNotHaveMultipleNetwork(machines)
+	})
+
+	It("nodes should be present in correct subnets per Nutanix failure domain", func() {
+		failIfNodeNotInMachineNetwork(nodes)
+	})
+
+	It("machines should have all specified subnets associated with their failure domain", func() {
+		failIfMachinesDoesNotContainAllSubnet(machines, machineNetworks)
+	})
+
+	It("machines should have all unique IPs for all subnets", func() {
+		failIfMachinesIfDuplicateIP(machines)
+	})
+
+	It("new machines should pass multi network tests [apigroup:machine.openshift.io][Suite:openshift/conformance/serial]", Label("Serial"), func() {
+		machineSets, err := e2eutil.GetMachineSets(cfg)
+		Expect(err).NotTo(HaveOccurred())
+
+		Expect(len(machineSets.Items)).ShouldNot(Equal(0))
+
+		machineSet := machineSets.Items[0]
+		origReplicas := int(*machineSet.Spec.Replicas)
+		// scale up new machine and wait for scale up to complete
+		By("scaling up a new machineset which should have multiple NICs")
+		err = e2eutil.ScaleMachineSet(cfg, machineSet.Name, origReplicas+1)
+		Expect(err).NotTo(HaveOccurred())
+
+		// Verify / wait for machine is ready
+		By("verifying machine became ready")
+		Eventually(func() (int32, error) {
+			ms, err := mc.MachineSets(e2eutil.MachineAPINamespace).Get(ctx, machineSet.Name, metav1.GetOptions{})
+			if err != nil {
+				return -1, err
+			}
+			return ms.Status.ReadyReplicas, nil
+		}, machineReadyTimeout).Should(BeEquivalentTo(origReplicas + 1))
+
+		nodes, err = c.CoreV1().Nodes().List(ctx, metav1.ListOptions{})
+		Expect(err).NotTo(HaveOccurred())
+
+		machines, err = mc.Machines("openshift-machine-api").List(ctx, metav1.ListOptions{})
+		Expect(err).NotTo(HaveOccurred())
+
+		By("determining common port groups among machines")
+		for _, machine := range machines.Items {
+			_, err := ProviderSpecFromRawExtension(machine.Spec.ProviderSpec.Value)
+			Expect(err).NotTo(HaveOccurred())
+		}
+
+		failIfNodeNotInMachineNetwork(nodes)
+		failIfMachinesNotHaveMultipleNetwork(machines)
+		failIfMachinesDoesNotContainAllSubnet(machines, machineNetworks)
+		failIfMachinesIfDuplicateIP(machines)
+
+		// Scale down machineset
+		By("scaling down the machineset")
+		err = e2eutil.ScaleMachineSet(cfg, machineSet.Name, origReplicas)
+		Expect(err).NotTo(HaveOccurred())
+
+		// Verify / wait for machine is removed
+		By("verifying machine is destroyed")
+		Eventually(func() (int32, error) {
+			ms, err := mc.MachineSets(e2eutil.MachineAPINamespace).Get(ctx, machineSet.Name, metav1.GetOptions{})
+			if err != nil {
+				return -1, err
+			}
+			return ms.Status.ReadyReplicas, nil
+		}, machineReadyTimeout).Should(BeEquivalentTo(origReplicas))
+	})
+})
diff --git a/test/e2e/nutanix/util.go b/test/e2e/nutanix/util.go
new file mode 100644
index 000000000..c7e137cd5
--- /dev/null
+++ b/test/e2e/nutanix/util.go
@@ -0,0 +1,55 @@
+package nutanix
+
+import (
+	"encoding/json"
+	"fmt"
+	"net"
+	"time"
+
+	machinev1 "github.com/openshift/api/machine/v1"
+	machinev1beta1 "github.com/openshift/api/machine/v1beta1"
+	"k8s.io/apimachinery/pkg/runtime"
+	"k8s.io/klog/v2"
+)
+
+const (
+	machineReadyTimeout = time.Minute * 6
+)
+
+func isIpInCidrRange(ip string, cidr string) (bool, error) {
+	parsed := net.ParseIP(ip)
+	_, ipnet, err := net.ParseCIDR(cidr)
+	if err != nil {
+		return false, fmt.Errorf("unable to parse address: %v", err)
+	}
+
+	return ipnet.Contains(parsed), nil
+}
+
+func ProviderSpecFromRawExtension(rawExtension *runtime.RawExtension) (*machinev1.NutanixMachineProviderConfig, error) {
+	if rawExtension == nil {
+		return &machinev1.NutanixMachineProviderConfig{}, nil
+	}
+
+	spec := new(machinev1.NutanixMachineProviderConfig)
+	if err := json.Unmarshal(rawExtension.Raw, &spec); err != nil {
+		return nil, fmt.Errorf("error unmarshalling providerSpec: %v", err)
+	}
+
+	klog.V(5).Infof("Got provider spec from raw extension: %+v", spec)
+	return spec, nil
+}
+
+func getMachinesInFailureDomain(machines *machinev1beta1.MachineList, failureDomainName string) ([]machinev1beta1.Machine, error) {
+	failureDomainMachines := []machinev1beta1.Machine{}
+	for _, machine := range machines.Items {
+		spec, err := ProviderSpecFromRawExtension(machine.Spec.ProviderSpec.Value)
+		if err != nil {
+			return nil, fmt.Errorf("error unmarshalling providerSpec: %v", err)
+		}
+		if spec.FailureDomain.Name == failureDomainName {
+			failureDomainMachines = append(failureDomainMachines, machine)
+		}
+	}
+	return failureDomainMachines, nil
+}