Update publications.html

Author: balicea

publications.html

@@ -147,10 +147,10 @@ <h2>Geppetto: a reusable modular open platform for exploring neuroscience data a
 
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-			<h2>c302: a multiscale framework for modelling the nervous system of Caenorhabditis elegans</h2>
+			<h2>c302: a multiscale framework for modelling the nervous system of _Caenorhabditis elegans_</h2>
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-			    10 September 2018, Phil. Trans. R. Soc. B, DOI: 10.1098/rstb.2017.0379
+			    10 September 2018, _Phil. Trans. R. Soc. B_, doi:10.1098/rstb.2017.0379
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 			    Padraig Gleeson, David Lung, Radu Grosu, Ramin Hasani and Stephen D. Larson
@@ -171,10 +171,10 @@ <h2>c302: a multiscale framework for modelling the nervous system of Caenorhabdi
 
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-			<h2>Three-dimensional simulation of the Caenorhabditis elegans body and muscle cells in liquid and gel environments for behavioural analysis</h2>
+			<h2>Three-dimensional simulation of the _Caenorhabditis elegans_ body and muscle cells in liquid and gel environments for behavioural analysis</h2>
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-			    10 September 2018, Phil. Trans. R. Soc. B, DOI: 10.1098/rstb.2017.0376
+			    10 September 2018, _Phil. Trans. R. Soc. B_, doi:10.1098/rstb.2017.0376
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 			    Andrey Palyanov, Sergey Khayrulin and Stephen D. Larson
@@ -259,12 +259,30 @@ <h2>Unit Testing, Model Validation, and Biological Simulation</h2>
 			    <a href="https://f1000research.com/articles/5-1946/v1" target="_blank">Read more</a>.
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+			<h2>Quantifying Mosaic Development: Towards an Evo-Devo Postmodern Synthesis of the Evolution of Development Via Differentiation Trees of Embryos</h2>
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+			    18 August 2016, _Biology_, 5(3), 33. doi:10.3390/biology5030033
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+			    Bradly Alicea and Richard Gordon
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+Embryonic development proceeds through a series of differentiation events. The mosaic version of this process (binary cell divisions) can be analyzed by comparing early development of _Ciona intestinalis_ and _Caenorhabditis elegans_. To do this, we reorganize lineage trees into differentiation trees using the graph theory ordering of relative cell volume. Lineage and differentiation trees provide us with means to classify each cell using binary codes. Extracting data characterizing lineage tree position, cell volume, and nucleus position for each cell during early embryogenesis, we conduct several statistical analyses, both within and between taxa. We compare both cell volume distributions and cell volume across developmental time within and between single species and assess differences between lineage tree and differentiation tree orderings. This enhances our understanding of the differentiation events in a model of pure mosaic embryogenesis and its relationship to evolutionary conservation. We also contribute several new techniques for assessing both differences between lineage trees and differentiation trees, and differences between differentiation trees of different species. The results suggest that at the level of differentiation trees, there are broad similarities between distantly related mosaic embryos that might be essential to understanding evolutionary change and phylogeny reconstruction. Differentiation trees may therefore provide a basis for an Evo-Devo Postmodern Synthesis.
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+			    <a href="https://royalsocietypublishing.org/doi/10.1098/rstb.2017.0381" target="_blank">Read more</a>.
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 			<h2>The OpenWorm Project: currently available resources and future plans</h2>
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-			    July 18 2015, BMC Neuroscience., DOI: 10.1186/1471-2202-16-S1-P141
+			    July 18 2015, _BMC Neuroscience_, DOI: 10.1186/1471-2202-16-S1-P141
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 			    Padraig Gleeson, Matteo Cantarelli, Michael Currie, Jim Hokanson, Giovanni Idili, Sergey Khayrulin, Andrey Palyanov, Balazs Szigeti and Stephen Larson