diff --git a/src/flask_sqlalchemy/extension.py b/src/flask_sqlalchemy/extension.py
index ccae54b4..a6758016 100644
--- a/src/flask_sqlalchemy/extension.py
+++ b/src/flask_sqlalchemy/extension.py
@@ -544,6 +544,11 @@ def _make_declarative_base(
         elif len(declarative_bases) == 1:
             body = dict(model_class.__dict__)
             body["__fsa__"] = self
+            # Default to *not* using SQLAlchemy's dataclass transform for db.Model.
+            # This avoids "ORM Annotated Dataclasses do not support a pre-existing '__table__' element"
+            # when a model sets __table__ explicitly (as in test_explicit_table).
+            # Individual models can opt back in with __sa_dataclass__ = True if desired.
+            body.setdefault("__sa_dataclass__", False)
             mixin_classes = [BindMixin, NameMixin, Model]
             if disable_autonaming:
                 mixin_classes.remove(NameMixin)
diff --git a/src/flask_sqlalchemy/model.py b/src/flask_sqlalchemy/model.py
index 6468a734..cbe0ccf1 100644
--- a/src/flask_sqlalchemy/model.py
+++ b/src/flask_sqlalchemy/model.py
@@ -79,6 +79,12 @@ class BindMetaMixin(type):
     def __init__(
         cls, name: str, bases: tuple[type, ...], d: dict[str, t.Any], **kwargs: t.Any
     ) -> None:
+        # If mapped-as-dataclass is globally enabled, classes that declare an
+        # explicit __table__ must opt out; otherwise SQLAlchemy 2.x raises:
+        # "ORM Annotated Dataclasses do not support a pre-existing '__table__' element".
+        if "__table__" in cls.__dict__ and getattr(cls, "__sa_dataclass__", None) is not False:
+            cls.__sa_dataclass__ = False
+
         if not ("metadata" in cls.__dict__ or "__table__" in cls.__dict__):
             bind_key = getattr(cls, "__bind_key__", None)
             parent_metadata = getattr(cls, "metadata", None)
@@ -109,6 +115,10 @@ class BindMixin:
 
     @classmethod
     def __init_subclass__(cls: type[BindMixin], **kwargs: dict[str, t.Any]) -> None:
+        # See note in NameMixin: explicit __table__ + mapped-as-dataclass are incompatible.
+        if "__table__" in cls.__dict__ and getattr(cls, "__sa_dataclass__", None) is not False:
+            cls.__sa_dataclass__ = False
+
         if not ("metadata" in cls.__dict__ or "__table__" in cls.__dict__) and hasattr(
             cls, "__bind_key__"
         ):
@@ -136,6 +146,11 @@ class NameMetaMixin(type):
     def __init__(
         cls, name: str, bases: tuple[type, ...], d: dict[str, t.Any], **kwargs: t.Any
     ) -> None:
+        # See note above: explicit __table__ + dataclass transform are incompatible.
+        # Opt out early during metaclass initialization.
+        if "__table__" in cls.__dict__ and getattr(cls, "__sa_dataclass__", None) is not False:
+            cls.__sa_dataclass__ = False
+
         if should_set_tablename(cls):
             cls.__tablename__ = camel_to_snake_case(cls.__name__)
 
@@ -206,6 +221,12 @@ class NameMixin:
 
     @classmethod
     def __init_subclass__(cls: type[NameMixin], **kwargs: dict[str, t.Any]) -> None:
+        # If mapped-as-dataclass is globally enabled, models that declare an
+        # explicit __table__ must opt out, otherwise SQLAlchemy raises:
+        # "ORM Annotated Dataclasses do not support a pre-existing '__table__' element".
+        if "__table__" in cls.__dict__ and getattr(cls, "__sa_dataclass__", None) is not False:
+            cls.__sa_dataclass__ = False
+
         if should_set_tablename(cls):
             cls.__tablename__ = camel_to_snake_case(cls.__name__)