diff --git a/pandas/core/api.py b/pandas/core/api.py
index c8a4e9d8a23b2..d7f40af5ef0fe 100644
--- a/pandas/core/api.py
+++ b/pandas/core/api.py
@@ -67,7 +67,7 @@
 )
 from pandas.core.indexes.period import period_range
 from pandas.core.indexes.timedeltas import timedelta_range
-from pandas.core.indexing import IndexSlice
+from pandas.core.indexing import IndexSlice as _IndexSlice
 from pandas.core.series import Series
 from pandas.core.tools.datetimes import to_datetime
 from pandas.core.tools.numeric import to_numeric
@@ -79,6 +79,8 @@
 # DataFrame needs to be imported after NamedAgg to avoid a circular import
 from pandas.core.frame import DataFrame  # isort:skip
 
+IndexSlice = _IndexSlice()
+
 __all__ = [
     "array",
     "ArrowDtype",
diff --git a/pandas/core/indexing.py b/pandas/core/indexing.py
index 0d6d7e68f58a4..4003eb0e5f1cb 100644
--- a/pandas/core/indexing.py
+++ b/pandas/core/indexing.py
@@ -24,7 +24,10 @@
     LossySetitemError,
 )
 from pandas.errors.cow import _chained_assignment_msg
-from pandas.util._decorators import doc
+from pandas.util._decorators import (
+    doc,
+    set_module,
+)
 
 from pandas.core.dtypes.cast import (
     can_hold_element,
@@ -98,7 +101,8 @@
 
 
 # the public IndexSlicerMaker
-class _IndexSlice:
+@set_module("pandas")
+class IndexSlice:
     """
     Create an object to more easily perform multi-index slicing.
 
@@ -145,9 +149,6 @@ def __getitem__(self, arg):
         return arg
 
 
-IndexSlice = _IndexSlice()
-
-
 class IndexingMixin:
     """
     Mixin for adding .loc/.iloc/.at/.iat to Dataframes and Series.
diff --git a/pandas/tests/api/test_api.py b/pandas/tests/api/test_api.py
index 75f9958b16286..3f659a15b97c9 100644
--- a/pandas/tests/api/test_api.py
+++ b/pandas/tests/api/test_api.py
@@ -417,6 +417,7 @@ def test_set_module():
     assert pd.Period.__module__ == "pandas"
     assert pd.Timestamp.__module__ == "pandas"
     assert pd.Timedelta.__module__ == "pandas"
+    assert pd.IndexSlice.__module__ == "pandas"
     assert pd.isna.__module__ == "pandas"
     assert pd.notna.__module__ == "pandas"
     assert pd.merge.__module__ == "pandas"