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mtb_ExpEvo_RNA

Scripts and data for differential expression analyses from publication "Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth"

DEFiles

Differential expression results for all comparisons and populations

HTSeqCounts

Raw expression counts from sequence analysis pipeline

Metadata

All metadata associated with samples from this study, including the annotation file used for expression counts.

Differential expression analyses

Anc BvP - comparison of biofilm to planktonic gene expression in ancestral populations

B EvA - comparison of evolved to ancestral gene expression in biofilm populations

Data QC – batch effects, biological replicate concordance, etc

Duplication - analysis of differential expression within large duplication

Evo BvP - comparison of biofilm to planktonic gene expression in evolved populations

P EvA - comparison of evolved to ancestral gene expression in planktonic populations

Sautons & Stationary – analysis of effects of media and growth phase on the transcriptome

ncRNA sORF - analysis of differential expression of ncRNAs and sORFs