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lines changed Original file line number Diff line number Diff line change @@ -5,7 +5,7 @@ The Vascular Model
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77The Vascular Model was originally proposed by Ostergaard et al [1 ]_. and was used for the analysis of DSC
8- data (within a Bayesian like algorithm) by Mouridsen et al. 2006 [2 ]_. The basic principle follows all
8+ data (within a Bayesian like algorithm) by Mouridsen et al. [2 ]_. The basic principle follows all
99tracer kinetic studies and treats the concentration of contrast agent in the tissue as the convolution
1010of an arterial input function (AIF) and a residue function.
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@@ -59,7 +59,7 @@ The Modified Vascular Model
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6060VERBENA implements a modified version of the Vascular Model whereby the MTT is not pre-calculated
6161from the data, but instead is a further parameter to be estimated as part of the inference applied
62- to the data, see Chappell et al [ 3 ]_ . This removes the risk of bias from the separate MTT calculation and
62+ to the data. This removes the risk of bias from the separate MTT calculation and
6363also allows for a separate macro vascular component to be implemented within the model.
6464
6565The other model parameter used by Verbena is named lambda and is identified with :math: `\alpha `.
@@ -101,7 +101,6 @@ by multiplicative factors each in the range :math:`[0, 1]` with :math:`R(C_{n+1}
101101The CPI method allows great flexibility in the shape of the :math: `R(t)` however this is at the cost
102102of larger numbers of model parameters.
103103
104-
105104References
106105----------
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