Brand new install of Pop!.
Using default fonts and all, haven't done much besides installing a few things.
I installed Microsoft Edge, and noticed that all text which isn't part of the web pages, and the tab which opens when you click "settings" in Edge, looks wonky.
So this applies to for example the names of the bookmarks on the bookmarks tab, the characters in the URL field, etc.
When changing the scaling factor of the fonts (in my case via gnome-tweaks) to anything above 1.00, the characters turn normal.
Pictures below are using a scaling factor of 1.01:
For reference, I did not experience this behavior in Firefox, OS menus etc, but did have it appear in the chat message field in Discord as well.