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As it seems Mash does not easily provide per-read or per-contig classification, it will be difficult to perform contamination filtering using only Mash. In order to perform read-based and/or contig-based contamination filtering, we should implement Kraken into Proksee.
We should still leverage Mash in the early stages for species selection, and for recognizing from a very high-level the possibility of contamination.
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enhancementNew feature or requestNew feature or request