diff --git a/xarray/tests/test_backends.py b/xarray/tests/test_backends.py
index 1842d6e3fc3..6fa1402c1f3 100644
--- a/xarray/tests/test_backends.py
+++ b/xarray/tests/test_backends.py
@@ -7520,6 +7520,10 @@ def test_zarr_append_chunk_partial(self):
                     mode="a",
                 )
 
+    @pytest.mark.xfail(
+        ON_WINDOWS,
+        reason="Permission errors from Zarr: https://github.com/pydata/xarray/pull/10793",
+    )
     @requires_dask
     def test_zarr_region_chunk_partial_offset(self):
         # https://github.com/pydata/xarray/pull/8459#issuecomment-1819417545