diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 02da624f..d56f905e 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -103,15 +103,15 @@ jobs:
           python: '3.10'
           allow_failure: false
 
-        - name: py311-dj51-mysql_innodb-coverage
+        - name: py311-dj51-mysql-coverage
           python: '3.11'
           allow_failure: false
 
-        - name: py310-dj42-mysql_innodb-coverage
+        - name: py310-dj42-mysql-coverage
           python: '3.10'
           allow_failure: false
 
-        - name: py39-dj42-mysql_innodb-xdist-coverage
+        - name: py39-dj42-mysql-xdist-coverage
           python: '3.9'
           allow_failure: false
 
@@ -135,10 +135,6 @@ jobs:
           python: '3.8'
           allow_failure: false
 
-        - name: py311-dj42-mysql_myisam-coverage
-          python: '3.11'
-          allow_failure: false
-
         # Explicitly test min pytest.
         - name: py38-dj42-sqlite-pytestmin-coverage
           python: '3.8'
diff --git a/docs/changelog.rst b/docs/changelog.rst
index 51395c74..0f181dde 100644
--- a/docs/changelog.rst
+++ b/docs/changelog.rst
@@ -7,8 +7,8 @@ v4.11.0 (Not released yet)
 Compatibility
 ^^^^^^^^^^^^^
 
-* Added official support for Django 5.2.
-
+* Added official support for Django 5.2 (`PR #1179 <https://github.com/pytest-dev/pytest-django/pull/1179>`__).
+* Dropped testing on MySQL’s MyISAM storage engine (`PR #1180 <https://github.com/pytest-dev/pytest-django/pull/1180>`__).
 
 v4.10.0 (2025-02-10)
 --------------------
diff --git a/docs/contributing.rst b/docs/contributing.rst
index 3914da38..d5003fc7 100644
--- a/docs/contributing.rst
+++ b/docs/contributing.rst
@@ -140,7 +140,7 @@ writing), running them all will take a long time. All valid configurations can
 be found in `tox.ini`. To test against a few of them, invoke tox with the `-e`
 flag::
 
-    $ tox -e py38-dj32-postgres,py310-dj41-mysql_innodb
+    $ tox -e py38-dj32-postgres,py310-dj41-mysql
 
 This will run the tests on Python 3.8/Django 3.2/PostgeSQL and Python
 3.10/Django 4.1/MySQL.
diff --git a/pytest_django_test/settings_mysql_innodb.py b/pytest_django_test/settings_mysql.py
similarity index 88%
rename from pytest_django_test/settings_mysql_innodb.py
rename to pytest_django_test/settings_mysql.py
index e744c9f3..cb53559f 100644
--- a/pytest_django_test/settings_mysql_innodb.py
+++ b/pytest_django_test/settings_mysql.py
@@ -11,7 +11,6 @@
         "PASSWORD": environ.get("TEST_DB_PASSWORD", ""),
         "HOST": environ.get("TEST_DB_HOST", "localhost"),
         "OPTIONS": {
-            "init_command": "SET default_storage_engine=InnoDB",
             "charset": "utf8mb4",
         },
         "TEST": {
@@ -26,7 +25,6 @@
         "PASSWORD": environ.get("TEST_DB_PASSWORD", ""),
         "HOST": environ.get("TEST_DB_HOST", "localhost"),
         "OPTIONS": {
-            "init_command": "SET default_storage_engine=InnoDB",
             "charset": "utf8mb4",
         },
         "TEST": {
@@ -42,7 +40,6 @@
         "PASSWORD": environ.get("TEST_DB_PASSWORD", ""),
         "HOST": environ.get("TEST_DB_HOST", "localhost"),
         "OPTIONS": {
-            "init_command": "SET default_storage_engine=InnoDB",
             "charset": "utf8mb4",
         },
         "TEST": {
diff --git a/pytest_django_test/settings_mysql_myisam.py b/pytest_django_test/settings_mysql_myisam.py
deleted file mode 100644
index 54ec8c93..00000000
--- a/pytest_django_test/settings_mysql_myisam.py
+++ /dev/null
@@ -1,53 +0,0 @@
-from os import environ
-
-from .settings_base import *  # noqa: F403
-
-
-DATABASES = {
-    "default": {
-        "ENGINE": "django.db.backends.mysql",
-        "NAME": "pytest_django_tests_default",
-        "USER": environ.get("TEST_DB_USER", "root"),
-        "PASSWORD": environ.get("TEST_DB_PASSWORD", ""),
-        "HOST": environ.get("TEST_DB_HOST", "localhost"),
-        "OPTIONS": {
-            "init_command": "SET default_storage_engine=MyISAM",
-            "charset": "utf8mb4",
-        },
-        "TEST": {
-            "CHARSET": "utf8mb4",
-            "COLLATION": "utf8mb4_unicode_ci",
-        },
-    },
-    "replica": {
-        "ENGINE": "django.db.backends.mysql",
-        "NAME": "pytest_django_tests_replica",
-        "USER": environ.get("TEST_DB_USER", "root"),
-        "PASSWORD": environ.get("TEST_DB_PASSWORD", ""),
-        "HOST": environ.get("TEST_DB_HOST", "localhost"),
-        "OPTIONS": {
-            "init_command": "SET default_storage_engine=MyISAM",
-            "charset": "utf8mb4",
-        },
-        "TEST": {
-            "MIRROR": "default",
-            "CHARSET": "utf8mb4",
-            "COLLATION": "utf8mb4_unicode_ci",
-        },
-    },
-    "second": {
-        "ENGINE": "django.db.backends.mysql",
-        "NAME": "pytest_django_tests_second",
-        "USER": environ.get("TEST_DB_USER", "root"),
-        "PASSWORD": environ.get("TEST_DB_PASSWORD", ""),
-        "HOST": environ.get("TEST_DB_HOST", "localhost"),
-        "OPTIONS": {
-            "init_command": "SET default_storage_engine=MyISAM",
-            "charset": "utf8mb4",
-        },
-        "TEST": {
-            "CHARSET": "utf8mb4",
-            "COLLATION": "utf8mb4_unicode_ci",
-        },
-    },
-}
diff --git a/tox.ini b/tox.ini
index 6e7472c5..aed0b8a3 100644
--- a/tox.ini
+++ b/tox.ini
@@ -17,8 +17,7 @@ deps =
     dj50: Django>=5.0,<5.1
     dj42: Django>=4.2,<4.3
 
-    mysql_myisam: mysqlclient==2.1.0
-    mysql_innodb: mysqlclient==2.1.0
+    mysql: mysqlclient==2.1.0
 
     postgres: psycopg[binary]
     coverage: coverage[toml]
@@ -28,8 +27,7 @@ deps =
     xdist: pytest-xdist>=1.15
 
 setenv =
-    mysql_innodb: DJANGO_SETTINGS_MODULE=pytest_django_test.settings_mysql_innodb
-    mysql_myisam: DJANGO_SETTINGS_MODULE=pytest_django_test.settings_mysql_myisam
+    mysql: DJANGO_SETTINGS_MODULE=pytest_django_test.settings_mysql
     postgres:     DJANGO_SETTINGS_MODULE=pytest_django_test.settings_postgres
     sqlite:       DJANGO_SETTINGS_MODULE=pytest_django_test.settings_sqlite
     sqlite_file:  DJANGO_SETTINGS_MODULE=pytest_django_test.settings_sqlite_file