diff --git a/newsfragments/3324.bugfix.rst b/newsfragments/3324.bugfix.rst
new file mode 100644
index 000000000..0fd5a0539
--- /dev/null
+++ b/newsfragments/3324.bugfix.rst
@@ -0,0 +1,2 @@
+Avoid having `trio.as_safe_channel` raise if closing the generator wrapped
+`GeneratorExit` in a `BaseExceptionGroup`.
diff --git a/src/trio/_channel.py b/src/trio/_channel.py
index 9caa7f769..2afca9d7c 100644
--- a/src/trio/_channel.py
+++ b/src/trio/_channel.py
@@ -570,6 +570,8 @@ async def _move_elems_to_channel(
         # `async with send_chan` will eat exceptions,
         # see https://github.com/python-trio/trio/issues/1559
         with send_chan:
+            # replace try-finally with contextlib.aclosing once python39 is
+            # dropped:
             try:
                 task_status.started()
                 while True:
@@ -582,7 +584,32 @@ async def _move_elems_to_channel(
                     # Send the value to the channel
                     await send_chan.send(value)
             finally:
-                # replace try-finally with contextlib.aclosing once python39 is dropped
-                await agen.aclose()
+                # work around `.aclose()` not suppressing GeneratorExit in an
+                # ExceptionGroup:
+                # TODO: make an issue on CPython about this
+                try:
+                    await agen.aclose()
+                except BaseExceptionGroup as exceptions:
+                    removed, narrowed_exceptions = exceptions.split(GeneratorExit)
+
+                    # TODO: extract a helper to flatten exception groups
+                    removed_exceptions: list[BaseException | None] = [removed]
+                    genexits_seen = 0
+                    for e in removed_exceptions:
+                        if isinstance(e, BaseExceptionGroup):
+                            removed_exceptions.extend(e.exceptions)  # noqa: B909
+                        else:
+                            genexits_seen += 1
+
+                    if genexits_seen > 1:
+                        exc = AssertionError("More than one GeneratorExit found.")
+                        if narrowed_exceptions is None:
+                            narrowed_exceptions = exceptions.derive([exc])
+                        else:
+                            narrowed_exceptions = narrowed_exceptions.derive(
+                                [*narrowed_exceptions.exceptions, exc]
+                            )
+                    if narrowed_exceptions is not None:
+                        raise narrowed_exceptions from None
 
     return context_manager
diff --git a/src/trio/_tests/test_channel.py b/src/trio/_tests/test_channel.py
index f1556a153..85cd982a4 100644
--- a/src/trio/_tests/test_channel.py
+++ b/src/trio/_tests/test_channel.py
@@ -625,3 +625,73 @@ async def agen(events: list[str]) -> AsyncGenerator[None]:
                         events.append("body cancel")
                         raise
     assert events == ["body cancel", "agen cancel"]
+
+
+async def test_as_safe_channel_genexit_exception_group() -> None:
+    @as_safe_channel
+    async def agen() -> AsyncGenerator[None]:
+        try:
+            async with trio.open_nursery():
+                yield
+        except BaseException as e:
+            assert pytest.RaisesGroup(GeneratorExit).matches(e)  # noqa: PT017
+            raise
+
+    async with agen() as g:
+        async for _ in g:
+            break
+
+
+async def test_as_safe_channel_does_not_suppress_nested_genexit() -> None:
+    @as_safe_channel
+    async def agen() -> AsyncGenerator[None]:
+        yield
+
+    with pytest.RaisesGroup(GeneratorExit):
+        async with agen() as g, trio.open_nursery():
+            await g.receive()  # this is for coverage reasons
+            raise GeneratorExit
+
+
+async def test_as_safe_channel_genexit_filter() -> None:
+    async def wait_then_raise() -> None:
+        try:
+            await trio.sleep_forever()
+        except trio.Cancelled:
+            raise ValueError from None
+
+    @as_safe_channel
+    async def agen() -> AsyncGenerator[None]:
+        async with trio.open_nursery() as nursery:
+            nursery.start_soon(wait_then_raise)
+            yield
+
+    with pytest.RaisesGroup(ValueError):
+        async with agen() as g:
+            async for _ in g:
+                break
+
+
+async def test_as_safe_channel_swallowing_extra_exceptions() -> None:
+    async def wait_then_raise(ex: type[BaseException]) -> None:
+        try:
+            await trio.sleep_forever()
+        except trio.Cancelled:
+            raise ex from None
+
+    @as_safe_channel
+    async def agen(ex: type[BaseException]) -> AsyncGenerator[None]:
+        async with trio.open_nursery() as nursery:
+            nursery.start_soon(wait_then_raise, ex)
+            nursery.start_soon(wait_then_raise, GeneratorExit)
+            yield
+
+    with pytest.RaisesGroup(AssertionError):
+        async with agen(GeneratorExit) as g:
+            async for _ in g:
+                break
+
+    with pytest.RaisesGroup(ValueError, AssertionError):
+        async with agen(ValueError) as g:
+            async for _ in g:
+                break