diff --git a/Lib/pdb.py b/Lib/pdb.py
index 559517813cf600..1e1b5ea4f0a184 100755
--- a/Lib/pdb.py
+++ b/Lib/pdb.py
@@ -96,7 +96,7 @@ class Restart(Exception):
            "post_mortem", "help"]
 
 def find_function(funcname, filename):
-    cre = re.compile(r'def\s+%s\s*[(]' % re.escape(funcname))
+    cre = re.compile(r'def\s+%s(\s*\[.+\])?\s*[(]' % re.escape(funcname))
     try:
         fp = tokenize.open(filename)
     except OSError:
diff --git a/Lib/test/test_pdb.py b/Lib/test/test_pdb.py
index 1542bb3bee1aea..bd61de0ad3494c 100644
--- a/Lib/test/test_pdb.py
+++ b/Lib/test/test_pdb.py
@@ -352,6 +352,42 @@ def test_pdb_breakpoint_commands():
     4
     """
 
+def test_pdb_breakpoint_on_annotated_function_def():
+    """Test breakpoints on function definitions with annotation.
+
+    >>> def foo[T]():
+    ...     return 0
+
+    >>> def bar() -> int:
+    ...     return 0
+
+    >>> def foobar[T]() -> int:
+    ...     return 0
+
+    >>> reset_Breakpoint()
+
+    >>> def test_function():
+    ...     import pdb; pdb.Pdb(nosigint=True, readrc=False).set_trace()
+    ...     pass
+
+    >>> with PdbTestInput([  # doctest: +NORMALIZE_WHITESPACE
+    ...     'break foo',
+    ...     'break bar',
+    ...     'break foobar',
+    ...     'continue',
+    ... ]):
+    ...    test_function()
+    > <doctest test.test_pdb.test_pdb_breakpoint_on_annotated_function_def[4]>(3)test_function()
+    -> pass
+    (Pdb) break foo
+    Breakpoint 1 at <doctest test.test_pdb.test_pdb_breakpoint_on_annotated_function_def[0]>:1
+    (Pdb) break bar
+    Breakpoint 2 at <doctest test.test_pdb.test_pdb_breakpoint_on_annotated_function_def[1]>:1
+    (Pdb) break foobar
+    Breakpoint 3 at <doctest test.test_pdb.test_pdb_breakpoint_on_annotated_function_def[2]>:1
+    (Pdb) continue
+    """
+
 def test_pdb_breakpoints_preserved_across_interactive_sessions():
     """Breakpoints are remembered between interactive sessions
 
diff --git a/Misc/NEWS.d/next/Library/2024-10-23-17-45-40.gh-issue-125884.41E_PD.rst b/Misc/NEWS.d/next/Library/2024-10-23-17-45-40.gh-issue-125884.41E_PD.rst
new file mode 100644
index 00000000000000..684b1f282b143e
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2024-10-23-17-45-40.gh-issue-125884.41E_PD.rst
@@ -0,0 +1 @@
+Fixed the bug for :mod:`pdb` where it can't set breakpoints on functions with certain annotations.