diff --git a/Lib/nturl2path.py b/Lib/nturl2path.py
index 7e13ae3128333d..e5667bc9a3ca94 100644
--- a/Lib/nturl2path.py
+++ b/Lib/nturl2path.py
@@ -26,10 +26,11 @@ def url2pathname(url):
         # Skip past extra slash before UNC drive in URL path.
         url = url[1:]
     # Windows itself uses ":" even in URLs.
-    url = url.replace(':', '|')
-    if not '|' in url:
+    url = url.replace(':', '|', 1)
+    if '|' in url and not (url.startswith('|') or '/|' in url):
         # No drive specifier, just convert slashes
         # make sure not to convert quoted slashes :-)
+        url = url.replace('|', ':', 1)
         return urllib.parse.unquote(url.replace('/', '\\'))
     comp = url.split('|')
     if len(comp) != 2 or comp[0][-1] not in string.ascii_letters:
diff --git a/Misc/NEWS.d/next/Library/2024-12-07-22-59-49.gh-issue-126367.re6HS2.rst b/Misc/NEWS.d/next/Library/2024-12-07-22-59-49.gh-issue-126367.re6HS2.rst
new file mode 100644
index 00000000000000..1bf8e71d83c3f2
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2024-12-07-22-59-49.gh-issue-126367.re6HS2.rst
@@ -0,0 +1 @@
+Modified the :func:`~urllib.request.url2pathname` function in :mod:`urllib.request` to correctly handle DOS drive paths in URLs on Windows. Previously, the function produced incorrect results for UNC paths and raised OS errors for some paths.