diff --git a/Include/internal/pycore_stats.h b/Include/internal/pycore_stats.h
index ab649574f33dbf..24f239a2135b93 100644
--- a/Include/internal/pycore_stats.h
+++ b/Include/internal/pycore_stats.h
@@ -77,7 +77,7 @@ PyAPI_FUNC(PyObject*) _Py_GetSpecializationStats(void);
 #define RARE_EVENT_INTERP_INC(interp, name) \
     do { \
         /* saturating add */ \
-        int val = FT_ATOMIC_LOAD_UINT8_RELAXED(interp->rare_events.name); \
+        uint8_t val = FT_ATOMIC_LOAD_UINT8_RELAXED(interp->rare_events.name); \
         if (val < UINT8_MAX) { \
             FT_ATOMIC_STORE_UINT8(interp->rare_events.name, val + 1); \
         } \
diff --git a/Lib/test/test_generated_cases.py b/Lib/test/test_generated_cases.py
index d481cb07f757d8..fc34ac2fdc98ce 100644
--- a/Lib/test/test_generated_cases.py
+++ b/Lib/test/test_generated_cases.py
@@ -1601,7 +1601,7 @@ def test_instruction_size_macro(self):
             frame->instr_ptr = next_instr;
             next_instr += 1;
             INSTRUCTION_STATS(OP);
-            frame->return_offset = 1 ;
+            frame->return_offset = 1u ;
             DISPATCH();
         }
         """
diff --git a/Modules/_sre/sre.c b/Modules/_sre/sre.c
index e8943920043906..694a66818f90d8 100644
--- a/Modules/_sre/sre.c
+++ b/Modules/_sre/sre.c
@@ -2355,7 +2355,7 @@ match_getindex(MatchObject* self, PyObject* index)
     }
 
     // Check that i*2 cannot overflow to make static analyzers happy
-    assert(i <= SRE_MAXGROUPS);
+    assert((size_t)i <= SRE_MAXGROUPS);
     return i;
 }
 
diff --git a/Python/executor_cases.c.h b/Python/executor_cases.c.h
index af4c39d03afa86..e3f4e5bdb65fd5 100644
--- a/Python/executor_cases.c.h
+++ b/Python/executor_cases.c.h
@@ -1576,7 +1576,7 @@
             new_frame = _PyFrame_PushUnchecked(tstate, getitem, 2, frame);
             new_frame->localsplus[0] = container;
             new_frame->localsplus[1] = sub;
-            frame->return_offset = 6 ;
+            frame->return_offset = 6u ;
             stack_pointer[-3].bits = (uintptr_t)new_frame;
             stack_pointer += -2;
             assert(WITHIN_STACK_BOUNDS());
@@ -1944,8 +1944,8 @@
             gen->gi_frame_state = FRAME_EXECUTING;
             gen->gi_exc_state.previous_item = tstate->exc_info;
             tstate->exc_info = &gen->gi_exc_state;
-            assert( 2 + oparg <= UINT16_MAX);
-            frame->return_offset = (uint16_t)( 2 + oparg);
+            assert( 2u + oparg <= UINT16_MAX);
+            frame->return_offset = (uint16_t)( 2u + oparg);
             gen_frame->previous = frame;
             stack_pointer[-1].bits = (uintptr_t)gen_frame;
             break;
@@ -4544,7 +4544,7 @@
             gen->gi_exc_state.previous_item = tstate->exc_info;
             tstate->exc_info = &gen->gi_exc_state;
             gen_frame->previous = frame;
-            frame->return_offset = (uint16_t)( 2 + oparg);
+            frame->return_offset = (uint16_t)( 2u + oparg);
             stack_pointer[0].bits = (uintptr_t)gen_frame;
             stack_pointer += 1;
             assert(WITHIN_STACK_BOUNDS());
diff --git a/Python/generated_cases.c.h b/Python/generated_cases.c.h
index 19352a3f00b87b..6686206141a679 100644
--- a/Python/generated_cases.c.h
+++ b/Python/generated_cases.c.h
@@ -653,7 +653,7 @@
                 new_frame = _PyFrame_PushUnchecked(tstate, getitem, 2, frame);
                 new_frame->localsplus[0] = container;
                 new_frame->localsplus[1] = sub;
-                frame->return_offset = 6 ;
+                frame->return_offset = 6u ;
             }
             // _PUSH_FRAME
             {
@@ -1586,7 +1586,7 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    frame->return_offset = 4 ;
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -2641,7 +2641,7 @@
                         if (new_frame == NULL) {
                             JUMP_TO_LABEL(error);
                         }
-                        assert( 1 == 1);
+                        assert( 1u == 1);
                         frame->return_offset = 1;
                         DISPATCH_INLINED(new_frame);
                     }
@@ -2922,8 +2922,8 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    assert( 4 == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
-                    frame->return_offset = 4 ;
+                    assert( 4u == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -5821,7 +5821,7 @@
                 gen->gi_exc_state.previous_item = tstate->exc_info;
                 tstate->exc_info = &gen->gi_exc_state;
                 gen_frame->previous = frame;
-                frame->return_offset = (uint16_t)( 2 + oparg);
+                frame->return_offset = (uint16_t)( 2u + oparg);
             }
             // _PUSH_FRAME
             {
@@ -6460,7 +6460,7 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    frame->return_offset = 4 ;
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -6681,7 +6681,7 @@
                         if (new_frame == NULL) {
                             JUMP_TO_LABEL(error);
                         }
-                        assert( 1 == 1);
+                        assert( 1u == 1);
                         frame->return_offset = 1;
                         DISPATCH_INLINED(new_frame);
                     }
@@ -6832,8 +6832,8 @@
                     if (new_frame == NULL) {
                         JUMP_TO_LABEL(error);
                     }
-                    assert( 4 == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
-                    frame->return_offset = 4 ;
+                    assert( 4u == 1 + INLINE_CACHE_ENTRIES_CALL_KW);
+                    frame->return_offset = 4u ;
                     DISPATCH_INLINED(new_frame);
                 }
                 STACKREFS_TO_PYOBJECTS(arguments, total_args, args_o);
@@ -8231,7 +8231,7 @@
             stack_pointer += -1;
             assert(WITHIN_STACK_BOUNDS());
             new_frame->localsplus[1] = PyStackRef_FromPyObjectNew(name);
-            frame->return_offset = 10 ;
+            frame->return_offset = 10u ;
             DISPATCH_INLINED(new_frame);
         }
 
@@ -10678,8 +10678,8 @@
                     gen->gi_frame_state = FRAME_EXECUTING;
                     gen->gi_exc_state.previous_item = tstate->exc_info;
                     tstate->exc_info = &gen->gi_exc_state;
-                    assert( 2 + oparg <= UINT16_MAX);
-                    frame->return_offset = (uint16_t)( 2 + oparg);
+                    assert( 2u + oparg <= UINT16_MAX);
+                    frame->return_offset = (uint16_t)( 2u + oparg);
                     assert(gen_frame->previous == NULL);
                     gen_frame->previous = frame;
                     DISPATCH_INLINED(gen_frame);
@@ -10779,8 +10779,8 @@
                 gen->gi_frame_state = FRAME_EXECUTING;
                 gen->gi_exc_state.previous_item = tstate->exc_info;
                 tstate->exc_info = &gen->gi_exc_state;
-                assert( 2 + oparg <= UINT16_MAX);
-                frame->return_offset = (uint16_t)( 2 + oparg);
+                assert( 2u + oparg <= UINT16_MAX);
+                frame->return_offset = (uint16_t)( 2u + oparg);
                 gen_frame->previous = frame;
             }
             // _PUSH_FRAME
diff --git a/Tools/cases_generator/generators_common.py b/Tools/cases_generator/generators_common.py
index 9e60d219a71c4a..0b3d89660099de 100644
--- a/Tools/cases_generator/generators_common.py
+++ b/Tools/cases_generator/generators_common.py
@@ -443,7 +443,7 @@ def instruction_size(self,
         """Replace the INSTRUCTION_SIZE macro with the size of the current instruction."""
         if uop.instruction_size is None:
             raise analysis_error("The INSTRUCTION_SIZE macro requires uop.instruction_size to be set", tkn)
-        self.out.emit(f" {uop.instruction_size} ")
+        self.out.emit(f" {uop.instruction_size}u ")
         return True
 
     def _print_storage(self, reason:str, storage: Storage) -> None: