diff --git a/mypyc/lib-rt/exc_ops.c b/mypyc/lib-rt/exc_ops.c
index 85498420d2af..c2a220d280ee 100644
--- a/mypyc/lib-rt/exc_ops.c
+++ b/mypyc/lib-rt/exc_ops.c
@@ -123,11 +123,11 @@ static PyObject *CPy_GetTypeName(PyObject *type) {
     PyObject *module = NULL, *name = NULL;
     PyObject *full = NULL;
 
-    module = PyObject_GetAttrString(type, "__module__");
+    module = PyObject_GetAttr(type, mypyc_interned_str.__module__);
     if (!module || !PyUnicode_Check(module)) {
         goto out;
     }
-    name = PyObject_GetAttrString(type, "__qualname__");
+    name = PyObject_GetAttr(type, mypyc_interned_str.__qualname__);
     if (!name || !PyUnicode_Check(name)) {
         goto out;
     }
diff --git a/mypyc/lib-rt/librt_strings.c b/mypyc/lib-rt/librt_strings.c
index d97d0f571f5b..1acaefa77fef 100644
--- a/mypyc/lib-rt/librt_strings.c
+++ b/mypyc/lib-rt/librt_strings.c
@@ -449,5 +449,6 @@ static PyModuleDef librt_strings_module = {
 PyMODINIT_FUNC
 PyInit_strings(void)
 {
+    intern_strings();
     return PyModuleDef_Init(&librt_strings_module);
 }
diff --git a/mypyc/lib-rt/misc_ops.c b/mypyc/lib-rt/misc_ops.c
index 38472b33291f..3683f6e5d406 100644
--- a/mypyc/lib-rt/misc_ops.c
+++ b/mypyc/lib-rt/misc_ops.c
@@ -107,7 +107,7 @@ static bool _CPy_IsSafeMetaClass(PyTypeObject *metaclass) {
     // manage to work with TypingMeta and its friends.
     if (metaclass == &PyType_Type)
         return true;
-    PyObject *module = PyObject_GetAttrString((PyObject *)metaclass, "__module__");
+    PyObject *module = PyObject_GetAttr((PyObject *)metaclass, mypyc_interned_str.__module__);
     if (!module) {
         PyErr_Clear();
         return false;
@@ -242,7 +242,7 @@ PyObject *CPyType_FromTemplate(PyObject *template,
            sizeof(PyTypeObject) - sizeof(PyVarObject));
 
     if (bases != orig_bases) {
-        if (PyObject_SetAttrString((PyObject *)t, "__orig_bases__", orig_bases) < 0)
+        if (PyObject_SetAttr((PyObject *)t, mypyc_interned_str.__orig_bases__, orig_bases) < 0)
             goto error;
     }
 
@@ -285,7 +285,7 @@ PyObject *CPyType_FromTemplate(PyObject *template,
 
     // Reject anything that would give us a nontrivial __slots__,
     // because the layout will conflict
-    slots = PyObject_GetAttrString((PyObject *)t, "__slots__");
+    slots = PyObject_GetAttr((PyObject *)t, mypyc_interned_str.__slots__);
     if (slots) {
         // don't fail on an empty __slots__
         int is_true = PyObject_IsTrue(slots);
@@ -298,7 +298,7 @@ PyObject *CPyType_FromTemplate(PyObject *template,
         PyErr_Clear();
     }
 
-    if (PyObject_SetAttrString((PyObject *)t, "__module__", modname) < 0)
+    if (PyObject_SetAttr((PyObject *)t, mypyc_interned_str.__module__, modname) < 0)
         goto error;
 
     if (init_subclass((PyTypeObject *)t, NULL))
@@ -458,7 +458,7 @@ CPyPickle_GetState(PyObject *obj)
 {
     PyObject *attrs = NULL, *state = NULL;
 
-    attrs = PyObject_GetAttrString((PyObject *)Py_TYPE(obj), "__mypyc_attrs__");
+    attrs = PyObject_GetAttr((PyObject *)Py_TYPE(obj), mypyc_interned_str.__mypyc_attrs__);
     if (!attrs) {
         goto fail;
     }
@@ -734,7 +734,7 @@ int CPyStatics_Initialize(PyObject **statics,
 // Call super(type(self), self)
 PyObject *
 CPy_Super(PyObject *builtins, PyObject *self) {
-    PyObject *super_type = PyObject_GetAttrString(builtins, "super");
+    PyObject *super_type = PyObject_GetAttr(builtins, mypyc_interned_str.super);
     if (!super_type)
         return NULL;
     PyObject *result = PyObject_CallFunctionObjArgs(
@@ -889,7 +889,7 @@ CPy_CallReverseOpMethod(PyObject *left,
 PyObject *CPySingledispatch_RegisterFunction(PyObject *singledispatch_func,
                                              PyObject *cls,
                                              PyObject *func) {
-    PyObject *registry = PyObject_GetAttrString(singledispatch_func, "registry");
+    PyObject *registry = PyObject_GetAttr(singledispatch_func, mypyc_interned_str.registry);
     PyObject *register_func = NULL;
     PyObject *typing = NULL;
     PyObject *get_type_hints = NULL;
@@ -902,7 +902,7 @@ PyObject *CPySingledispatch_RegisterFunction(PyObject *singledispatch_func,
             // passed a class
             // bind cls to the first argument so that register gets called again with both the
             // class and the function
-            register_func = PyObject_GetAttrString(singledispatch_func, "register");
+            register_func = PyObject_GetAttr(singledispatch_func, mypyc_interned_str.register_);
             if (register_func == NULL) goto fail;
             return PyMethod_New(register_func, cls);
         }
@@ -923,7 +923,7 @@ PyObject *CPySingledispatch_RegisterFunction(PyObject *singledispatch_func,
         func = cls;
         typing = PyImport_ImportModule("typing");
         if (typing == NULL) goto fail;
-        get_type_hints = PyObject_GetAttrString(typing, "get_type_hints");
+        get_type_hints = PyObject_GetAttr(typing, mypyc_interned_str.get_type_hints);
 
         type_hints = PyObject_CallOneArg(get_type_hints, func);
         PyObject *argname;
@@ -944,7 +944,7 @@ PyObject *CPySingledispatch_RegisterFunction(PyObject *singledispatch_func,
     }
 
     // clear the cache so we consider the newly added function when dispatching
-    PyObject *dispatch_cache = PyObject_GetAttrString(singledispatch_func, "dispatch_cache");
+    PyObject *dispatch_cache = PyObject_GetAttr(singledispatch_func, mypyc_interned_str.dispatch_cache);
     if (dispatch_cache == NULL) goto fail;
     PyDict_Clear(dispatch_cache);
 
diff --git a/mypyc/lib-rt/static_data.c b/mypyc/lib-rt/static_data.c
index 1fc93330bdc1..cc503181dccd 100644
--- a/mypyc/lib-rt/static_data.c
+++ b/mypyc/lib-rt/static_data.c
@@ -17,8 +17,13 @@ mypyc_interned_str_struct mypyc_interned_str;
 int
 intern_strings(void) {
     INTERN_STRING(__init_subclass__, "__init_subclass__");
+    INTERN_STRING(__module__, "__module__");
     INTERN_STRING(__mro_entries__, "__mro_entries__");
+    INTERN_STRING(__mypyc_attrs__, "__mypyc_attrs__");
     INTERN_STRING(__name__, "__name__");
+    INTERN_STRING(__orig_bases__, "__orig_bases__");
+    INTERN_STRING(__qualname__, "__qualname__");
+    INTERN_STRING(__slots__, "__slots__");
     INTERN_STRING(__radd__, "__radd__");
     INTERN_STRING(__rsub__, "__rsub__");
     INTERN_STRING(__rmul__, "__rmul__");
@@ -42,12 +47,17 @@ intern_strings(void) {
     INTERN_STRING(clear, "clear");
     INTERN_STRING(close_, "close");
     INTERN_STRING(copy, "copy");
+    INTERN_STRING(dispatch_cache, "dispatch_cache");
+    INTERN_STRING(get_type_hints, "get_type_hints");
     INTERN_STRING(keys, "keys");
     INTERN_STRING(items, "items");
     INTERN_STRING(join, "join");
+    INTERN_STRING(register_, "register");
+    INTERN_STRING(registry, "registry");
     INTERN_STRING(send, "send");
     INTERN_STRING(setdefault, "setdefault");
     INTERN_STRING(startswith, "startswith");
+    INTERN_STRING(super, "super");
     INTERN_STRING(throw_, "throw");
     INTERN_STRING(translate, "translate");
     INTERN_STRING(update, "update");
diff --git a/mypyc/lib-rt/static_data.h b/mypyc/lib-rt/static_data.h
index f779504b6c20..c177979d9eb0 100644
--- a/mypyc/lib-rt/static_data.h
+++ b/mypyc/lib-rt/static_data.h
@@ -13,7 +13,12 @@ int intern_strings(void);
 
 typedef struct mypyc_interned_str_struct {
     PyObject *__init_subclass__;
+    PyObject *__module__;
     PyObject *__mro_entries__;
+    PyObject *__mypyc_attrs__;
+    PyObject *__orig_bases__;
+    PyObject *__qualname__;
+    PyObject *__slots__;
     PyObject *__name__;
     PyObject *__radd__;
     PyObject *__rsub__;
@@ -38,12 +43,17 @@ typedef struct mypyc_interned_str_struct {
     PyObject *clear;
     PyObject *close_;
     PyObject *copy;
+    PyObject *dispatch_cache;
+    PyObject *get_type_hints;
     PyObject *keys;
     PyObject *items;
     PyObject *join;
+    PyObject *register_;
+    PyObject *registry;
     PyObject *send;
     PyObject *setdefault;
     PyObject *startswith;
+    PyObject *super;
     PyObject *throw_;
     PyObject *translate;
     PyObject *update;