diff --git a/spec/std/isa/ext/Za64rs.yaml b/spec/std/isa/ext/Za64rs.yaml
index ce24a5980a..f31566e561 100644
--- a/spec/std/isa/ext/Za64rs.yaml
+++ b/spec/std/isa/ext/Za64rs.yaml
@@ -17,6 +17,7 @@ description: |
   [NOTE]
   The minimum reservation set size is effectively determined by the size of atomic accesses in
   the A extension.
+conflicts: Za128rs
 versions:
   - version: "1.0.0"
     state: ratified
diff --git a/spec/std/isa/profile/RVA22S64.yaml b/spec/std/isa/profile/RVA22S64.yaml
index 24f540e214..4924a32893 100644
--- a/spec/std/isa/profile/RVA22S64.yaml
+++ b/spec/std/isa/profile/RVA22S64.yaml
@@ -20,6 +20,12 @@ extensions:
   $inherits:
     - "profile/RVA20S64.yaml#/extensions"
     - "profile/RVA22U64.yaml#/extensions"
+  $remove:
+    - Za128rs
+    - Zfh
+    - V
+    - Zkn
+    - Zks
   S:
     presence: mandatory
     version: "= 1.12"
diff --git a/spec/std/isa/profile/RVA22U64.yaml b/spec/std/isa/profile/RVA22U64.yaml
index f84c532d7e..03c3545b6e 100644
--- a/spec/std/isa/profile/RVA22U64.yaml
+++ b/spec/std/isa/profile/RVA22U64.yaml
@@ -18,6 +18,12 @@ introduction: |
   terms of the amount of software that targets this profile.
 extensions:
   $inherits: "profile/RVA20U64.yaml#/extensions"
+  $remove: Za128rs
+  Za64rs:
+    presence: mandatory
+    version: "~>1.0"
+    note: |
+      Reservation sets are contiguous, naturally aligned, and a maximum of 64 bytes
   Zihpm:
     presence: mandatory
     version: "= 2.0"
diff --git a/spec/std/isa/profile/RVA23S64.yaml b/spec/std/isa/profile/RVA23S64.yaml
index 641a59c149..04d2494b66 100644
--- a/spec/std/isa/profile/RVA23S64.yaml
+++ b/spec/std/isa/profile/RVA23S64.yaml
@@ -23,6 +23,24 @@ extensions:
   $inherits:
     - "profile/RVB23S64.yaml#/extensions"
     - "profile/RVA23U64.yaml#/extensions"
+  $remove:
+    - Zfh
+    - Zkn
+    - Zks
+    - Zvkng
+    - Zvksg
+    - Zabha
+    - Zacas
+    - Ziccamoc
+    - Zvbc
+    - Zama16b
+    - Zbc
+    - Zicfilp
+    - Zicfiss
+    - Zvfh
+    - Zfbfmin
+    - Zvfbfmin
+    - Zvfbfwma
 
   #########################################################################
   # MANDATORY extensions in RVA23S64 (that were optional in RVB23S64)
diff --git a/spec/std/isa/profile/RVB23S64.yaml b/spec/std/isa/profile/RVB23S64.yaml
index 0ad6d5ba7d..3518fc946e 100644
--- a/spec/std/isa/profile/RVB23S64.yaml
+++ b/spec/std/isa/profile/RVB23S64.yaml
@@ -23,6 +23,29 @@ extensions:
   $inherits:
     - "profile/RVA22S64.yaml#/extensions"
     - "profile/RVB23U64.yaml#/extensions"
+  $remove:
+    - V
+    - Zvfhmin
+    - Zvbb
+    - Zvkt
+    - Supm
+    - Zvkng
+    - Zvksg
+    - Zvkg
+    - Zvknc
+    - Zvksc
+    - Zabha
+    - Zacas
+    - Ziccamoc
+    - Zvbc
+    - Zama16b
+    - Zbc
+    - Zicfilp
+    - Zicfiss
+    - Zvfh
+    - Zfbfmin
+    - Zvfbfmin
+    - Zvfbfwma
 
   #########################################################################
   # MANDATORY extensions in RVB23 (and RVA23)
diff --git a/spec/std/isa/profile/RVB23U64.yaml b/spec/std/isa/profile/RVB23U64.yaml
index b57fb74ab6..00a256165a 100644
--- a/spec/std/isa/profile/RVB23U64.yaml
+++ b/spec/std/isa/profile/RVB23U64.yaml
@@ -21,7 +21,6 @@ extensions:
   # imported from RVA22U64
   #########################################################################
   $inherits: "profile/RVA22U64.yaml#/extensions"
-  $remove: Za128rs
 
   #########################################################################
   # MANDATORY extensions in RVB23 (and RVA23)
@@ -61,11 +60,6 @@ extensions:
     version: "~>1.0"
     note: |
       Wait-on-reservation-set (WRS) instructions
-  Za64rs:
-    presence: mandatory
-    version: "~>1.0"
-    note: |
-      Reservation sets are contiguous, naturally aligned, and a maximum of 64 bytes
 
   #########################################################################
   # OPTIONAL LOCALIZED extensions