diff --git a/compiler/rustc_llvm/llvm-wrapper/RustWrapper.cpp b/compiler/rustc_llvm/llvm-wrapper/RustWrapper.cpp
index b8cef6a7e250e..b800cd792ae31 100644
--- a/compiler/rustc_llvm/llvm-wrapper/RustWrapper.cpp
+++ b/compiler/rustc_llvm/llvm-wrapper/RustWrapper.cpp
@@ -1565,9 +1565,17 @@ extern "C" LLVMValueRef LLVMRustBuildMemCpy(LLVMBuilderRef B, LLVMValueRef Dst,
                                             unsigned SrcAlign,
                                             LLVMValueRef Size,
                                             bool IsVolatile) {
-  return wrap(unwrap(B)->CreateMemCpy(unwrap(Dst), MaybeAlign(DstAlign),
-                                      unwrap(Src), MaybeAlign(SrcAlign),
-                                      unwrap(Size), IsVolatile));
+  if (unwrap(B)->GetInsertBlock()->getParent()->hasFnAttribute("no-builtins") ||
+      unwrap(B)->GetInsertBlock()->getParent()->hasFnAttribute(
+          "no-builtin-memcpy")) {
+    return wrap(unwrap(B)->CreateMemCpyInline(unwrap(Dst), MaybeAlign(DstAlign),
+                                              unwrap(Src), MaybeAlign(SrcAlign),
+                                              unwrap(Size), IsVolatile));
+  } else {
+    return wrap(unwrap(B)->CreateMemCpy(unwrap(Dst), MaybeAlign(DstAlign),
+                                        unwrap(Src), MaybeAlign(SrcAlign),
+                                        unwrap(Size), IsVolatile));
+  }
 }
 
 extern "C" LLVMValueRef
@@ -1583,8 +1591,16 @@ extern "C" LLVMValueRef LLVMRustBuildMemSet(LLVMBuilderRef B, LLVMValueRef Dst,
                                             unsigned DstAlign, LLVMValueRef Val,
                                             LLVMValueRef Size,
                                             bool IsVolatile) {
-  return wrap(unwrap(B)->CreateMemSet(unwrap(Dst), unwrap(Val), unwrap(Size),
-                                      MaybeAlign(DstAlign), IsVolatile));
+  if (unwrap(B)->GetInsertBlock()->getParent()->hasFnAttribute("no-builtins") ||
+      unwrap(B)->GetInsertBlock()->getParent()->hasFnAttribute(
+          "no-builtin-memset")) {
+    return wrap(unwrap(B)->CreateMemSetInline(unwrap(Dst), MaybeAlign(DstAlign),
+                                              unwrap(Val), unwrap(Size),
+                                              IsVolatile));
+  } else {
+    return wrap(unwrap(B)->CreateMemSet(unwrap(Dst), unwrap(Val), unwrap(Size),
+                                        MaybeAlign(DstAlign), IsVolatile));
+  }
 }
 
 // Polyfill for `LLVMBuildCallBr`, which was added in LLVM 19.
diff --git a/tests/codegen/no_builtin-mem.rs b/tests/codegen/no_builtin-mem.rs
new file mode 100644
index 0000000000000..8b81dcb6fdaf0
--- /dev/null
+++ b/tests/codegen/no_builtin-mem.rs
@@ -0,0 +1,16 @@
+#![crate_type = "lib"]
+#![no_builtins]
+
+type T = [u8; 256];
+
+#[no_mangle]
+pub fn f() -> [i32; 1000] {
+    // CHECK: call void @llvm.memset.inline.{{.*}}(ptr nonnull align 4 %{{.*}}, i8 0, i64 4000, i1 false)
+    [0; 1000]
+}
+
+#[no_mangle]
+pub fn g(x: &[i32; 1000], y: &mut [i32; 1000]) {
+    // CHECK: call void @llvm.memcpy.inline.{{.*}}(ptr nonnull align 4 %{{.*}}, ptr nonnull align 4 %{{.*}}, i64 4000, i1 false)
+    *y = *x;
+}