diff --git a/packages/destination-actions/src/destinations/salesforce-marketing-cloud/_tests_/multistatus.test.ts b/packages/destination-actions/src/destinations/salesforce-marketing-cloud/_tests_/multistatus.test.ts
index 48450e0d801..fd0f230430c 100644
--- a/packages/destination-actions/src/destinations/salesforce-marketing-cloud/_tests_/multistatus.test.ts
+++ b/packages/destination-actions/src/destinations/salesforce-marketing-cloud/_tests_/multistatus.test.ts
@@ -200,6 +200,71 @@ describe('Multistatus', () => {
         errorreporter: 'DESTINATION'
       })
     })
+
+    it('should mark "Unable to save rows for data extension ID" error as retryable even if SFMC returns 400', async () => {
+      const errorResponse = {
+        status: 400,
+        message: 'Invalid keys for ID: HS1',
+        additionalErrors: [
+          {
+            errorcode: 10006,
+            message: 'Unable to save rows for data extension ID'
+          }
+        ]
+      }
+
+      nock(requestUrl).post('').reply(400, errorResponse)
+
+      const events: SegmentEvent[] = [
+        createTestEvent({
+          type: 'track',
+          userId: 'harry-1',
+          properties: {
+            id: '1234567890',
+            keys: {
+              id: 'HS1' // Valid key
+            },
+            values: {
+              name: 'Harry Styles'
+            }
+          }
+        }),
+        createTestEvent({
+          type: 'track',
+          userId: 'harry-2',
+          properties: {
+            id: '1234567890',
+            keys: {
+              id: 'HS2' // Invalid key
+            },
+            values: {
+              name: 'Harry Potter'
+            }
+          }
+        })
+      ]
+
+      const response = await testDestination.executeBatch('dataExtension', {
+        events,
+        settings,
+        mapping
+      })
+
+      expect(response[0]).toMatchObject({
+        status: 500,
+        errortype: 'INTERNAL_SERVER_ERROR',
+        errormessage: 'Unable to save rows for data extension ID',
+        errorreporter: 'DESTINATION'
+      })
+
+      expect(response[1]).toMatchObject({
+        status: 500,
+        errortype: 'INTERNAL_SERVER_ERROR',
+        errormessage: 'Unable to save rows for data extension ID',
+        errorreporter: 'DESTINATION'
+      })
+    })
+
     it('should handle multistatus errors and set correct status code', async () => {
       const errorResponse = {
         status: 429,
@@ -467,6 +532,72 @@ describe('Multistatus', () => {
       })
     })
 
+    it('should mark "Unable to save rows for data extension ID" error as retryable even if SFMC returns 400', async () => {
+      const errorResponse = {
+        status: 400,
+        message: 'Invalid keys for ID: HS1',
+        additionalErrors: [
+          {
+            errorcode: 10006,
+            message: 'Unable to save rows for data extension ID'
+          }
+        ]
+      }
+
+      nock(requestUrl).post('').reply(400, errorResponse)
+
+      const events: SegmentEvent[] = [
+        createTestEvent({
+          type: 'track',
+          userId: 'harry-1',
+          properties: {
+            id: '1234567890',
+            keys: {
+              contactKey: 'harry-1',
+              id: 'HS1'
+            },
+            values: {
+              name: 'Harry Styles'
+            }
+          }
+        }),
+        createTestEvent({
+          type: 'track',
+          userId: 'harry-2',
+          properties: {
+            id: '1234567890',
+            keys: {
+              contactKey: 'harry-2',
+              id: 'HS2'
+            },
+            values: {
+              name: 'Harry Potter'
+            }
+          }
+        })
+      ]
+
+      const response = await testDestination.executeBatch('contactDataExtension', {
+        events,
+        settings,
+        mapping
+      })
+
+      expect(response[0]).toMatchObject({
+        status: 500,
+        errortype: 'INTERNAL_SERVER_ERROR',
+        errormessage: 'Unable to save rows for data extension ID',
+        errorreporter: 'DESTINATION'
+      })
+
+      expect(response[1]).toMatchObject({
+        status: 500,
+        errortype: 'INTERNAL_SERVER_ERROR',
+        errormessage: 'Unable to save rows for data extension ID',
+        errorreporter: 'DESTINATION'
+      })
+    })
+
     it('should handle multistatus errors and set correct status code', async () => {
       const errorResponse = {
         status: 429,
diff --git a/packages/destination-actions/src/destinations/salesforce-marketing-cloud/sfmc-operations.ts b/packages/destination-actions/src/destinations/salesforce-marketing-cloud/sfmc-operations.ts
index a111f86adce..273749a1814 100644
--- a/packages/destination-actions/src/destinations/salesforce-marketing-cloud/sfmc-operations.ts
+++ b/packages/destination-actions/src/destinations/salesforce-marketing-cloud/sfmc-operations.ts
@@ -141,9 +141,20 @@ export async function executeUpsertWithMultiStatus(
       err.response.data.additionalErrors.length > 0 &&
       err.response.data.additionalErrors
 
+    const retryableCodes = [10006]
+    const hasAnyRetryableError =
+      additionalError &&
+      additionalError.some(
+        (e) => retryableCodes.includes(e.errorcode) && e.message.includes('Unable to save rows for data extension ID')
+      )
+
+    let status = 500 // default status is 500
+    if (!hasAnyRetryableError && err?.response?.status) {
+      status = err.response.status
+    }
     payloads.forEach((_, index) => {
       multiStatusResponse.setErrorResponseAtIndex(index, {
-        status: err?.response?.status || 500,
+        status: status,
         errormessage: additionalError ? additionalError[0].message : errData?.message || '',
         sent: rows[index] as Object as JSONLikeObject,
         /*