diff --git a/.github/workflows/cron_debian.yml b/.github/workflows/cron_debian.yml
new file mode 100644
index 0000000000..6a8ebfe40e
--- /dev/null
+++ b/.github/workflows/cron_debian.yml
@@ -0,0 +1,72 @@
+# SPDX-FileCopyrightText: 2006-2025 Knut Reinert & Freie Universität Berlin
+# SPDX-FileCopyrightText: 2016-2025 Knut Reinert & MPI für molekulare Genetik
+# SPDX-License-Identifier: CC0-1.0
+
+name: Debian
+
+on:
+  schedule:
+    - cron: "0 1 * * THU"
+  workflow_dispatch:
+
+concurrency:
+  group: debian-${{ github.ref }}
+  cancel-in-progress: true
+
+env:
+  TZ: Europe/Berlin
+
+defaults:
+  run:
+    shell: bash -Eeuxo pipefail {0}
+
+jobs:
+  build:
+    name: Debian
+    runs-on: ubuntu-latest
+    if: github.repository_owner == 'seqan' || github.event_name == 'workflow_dispatch'
+    container:
+      image: debian:unstable
+    steps:
+      - name: Install Essentials
+        run: |
+          apt-get update
+          apt-get install --yes --no-install-recommends build-essential git cmake wget fakeroot ca-certificates
+
+      - name: Setup Repo
+        run: |
+          mkdir unstable && cd unstable
+          git clone --depth 1 https://github.com/seqan/seqan3.git
+          cd seqan3/
+          git remote add salsa https://salsa.debian.org/med-team/seqan3.git
+          git fetch --depth 1 salsa
+          git checkout salsa/debian/experimental -- debian
+
+      - name: Reduce Noise
+        working-directory: unstable/seqan3
+        run: |
+          if [[ -f test/cmake/seqan3_require_ccache.cmake ]]; then
+            echo "" > test/cmake/seqan3_require_ccache.cmake
+          fi
+          if [[ -f test/documentation/seqan3_doxygen_cfg.in ]]; then
+            sed -i 's@^\(QUIET\s*=\) NO@\1 YES@' test/documentation/seqan3_doxygen_cfg.in
+          fi
+
+      - name: Install Dependencies
+        working-directory: unstable/seqan3
+        run: apt-get build-dep --yes --no-install-recommends .
+
+      - name: Build
+        working-directory: unstable/seqan3
+        run: dpkg-buildpackage --unsigned-changes --unsigned-source --build=binary
+
+      - name: Upload Artifacts
+        if: always()
+        uses: actions/upload-artifact@v4
+        with:
+          name: debian-seqan3-artifacts
+          path: |
+            unstable/**/seqan3*.deb
+            unstable/**/libseqan3*.deb
+            unstable/**/seqan3*.changes
+            unstable/**/seqan3*.buildinfo