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config.toml
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12 lines (12 loc) · 814 Bytes
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# Module: hemostasis -- fibrin clot (provisional wound matrix)
# Sources: Clark 1996 (doi:10.1007/978-1-4615-1795-5),
# Laurens et al. 2006 (doi:10.1111/j.1538-7836.2006.01826.x)
[skin.hemostasis]
enabled = false # master switch (wound preset enables at runtime)
diffusion = 0.0 # immobile structural ECM
decay = 0.0003 # slow turnover (t1/2 ~230h ~ 10 days)
wound_seed = 1.0 # initial clot density in wound
tgfb_coupling = 0.0002 # fibrin -> TGF-beta production rate
fibronectin_coupling = 0.0003 # fibrin -> fibronectin co-deposition
mmp_degradation = 0.002 # MMP-mediated fibrinolysis rate
migration_boost = 0.3 # keratinocyte migration speed boost from fibrin