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llms.txt

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- [`calculate_log_penalty()`](https://statdivlab.github.io/tinyvamp/reference/calculate_log_penalty.md)
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: Calculate barrier penalty to add to objective function inside
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barrier algorithm
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- [`costea2017_metaphlan2_profiles`](https://statdivlab.github.io/tinyvamp/reference/costea2017_metaphlan2_profiles.md)
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: MetaPhlAn2 taxonomic profiles from the Costea 2017 study.
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- [`costea2017_mock_composition`](https://statdivlab.github.io/tinyvamp/reference/costea2017_mock_composition.md)
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: The composition of 10 spike-in taxa in 19 samples observed from flow
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cytometry.
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- [`costea2017_sample_data`](https://statdivlab.github.io/tinyvamp/reference/costea2017_sample_data.md)
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: costea2017_sample_data
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- [`dataframes_to_parameters()`](https://statdivlab.github.io/tinyvamp/reference/dataframes_to_parameters.md)
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: Convert parameter values stored in data frame format to matrix
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format
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- [`estimate_parameters()`](https://statdivlab.github.io/tinyvamp/reference/estimate_parameters.md)
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: Fit tinyvamp model to HTS microbiome data
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- [`evaluate_criterion_lr()`](https://statdivlab.github.io/tinyvamp/reference/evaluate_criterion_lr.md)
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: Criterion Evaluation Function
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- [`karstens_phyloseq`](https://statdivlab.github.io/tinyvamp/reference/karstens_phyloseq.md)
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: karstens_phyloseq
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- [`mu_d_P()`](https://statdivlab.github.io/tinyvamp/reference/mu_d_P.md)
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: Calculate derivative of mu_ij with respect to an entry of P
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- [`mu_d_beta()`](https://statdivlab.github.io/tinyvamp/reference/mu_d_beta.md)

pkgdown.yml

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articles:
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compare-experiments: compare-experiments.html
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dilution-series: dilution-series.html
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last_built: 2026-03-06T21:01Z
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last_built: 2026-03-07T00:27Z
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urls:
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reference: https://statdivlab.github.io/tinyvamp/reference
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article: https://statdivlab.github.io/tinyvamp/articles

reference/costea2017_metaphlan2_profiles.html

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# MetaPhlAn2 taxonomic profiles from the Costea 2017 study.
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MetaPhlAn2 taxonomic profiles from the Costea 2017 study.
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## Usage
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``` r
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costea2017_metaphlan2_profiles
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```
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## Format
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A data frame with the observed relative abundances (from MetaPhlAn2) of
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taxa (rows) in each sample (columns)
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## Source
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<https://doi.org/10.1038/nbt.3960>

reference/costea2017_sample_data.html

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# costea2017_sample_data
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Sample metadata for the Costea 2017 study.
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## Usage
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``` r
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costea2017_sample_data
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```
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## Format
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A data frame mapping samples to protocols and individuals
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## Source
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<https://doi.org/10.1038/nbt.3960>

reference/estimate_parameters.html

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reference/estimate_parameters.md

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Maximum value of barrier_t. Defaults to 1e12.
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- initial_conv_tol:
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Are we flat enough in the likelihood yet? Where to start.
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- final_conv_tol:
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Are we flat enough in the likelihood yet? Where to end.
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- constraint_tolerance:
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The tolerance for the augmented Lagrangian algorithm. Final estimates

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