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| 1 | +# This CITATION.cff file was generated with cffinit. |
| 2 | +# Visit https://bit.ly/cffinit to generate yours today! |
| 3 | + |
| 4 | +cff-version: 1.2.0 |
| 5 | +title: >- |
| 6 | + BamToCov, an efficient toolkit for sequence |
| 7 | + coverage calculations |
| 8 | +message: >- |
| 9 | + Please cite this dataset using the metadata from |
| 10 | + 'preferred-citation'. |
| 11 | +type: software |
| 12 | +authors: |
| 13 | + - given-names: Andrea |
| 14 | + family-names: Telatin |
| 15 | + email: andrea.telatin@quadram.ac.uk |
| 16 | + affiliation: Quadram Institute Bioscience |
| 17 | + orcid: 'https://orcid.org/0000-0001-7619-281X' |
| 18 | + - given-names: Giovanni |
| 19 | + family-names: Birolo |
| 20 | + email: giovanni.birolo@unito.it |
| 21 | + affiliation: University of Turin |
| 22 | +identifiers: |
| 23 | + - type: doi |
| 24 | + value: 10.1101/2021.11.12.466787 |
| 25 | + description: >- |
| 26 | + BamToCov: an efficient toolkit for sequence |
| 27 | + coverage calculations |
| 28 | +url: 'https://telatin.github.io/bamtocov/' |
| 29 | +abstract: > |
| 30 | + Motivation: Many genomics applications require the |
| 31 | + computation of nucleotide coverage of a reference |
| 32 | + genome or the ability to determine how many reads |
| 33 | + map to a reference region. |
| 34 | +
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| 35 | +
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| 36 | + Results: BamToCov is a toolkit for rapid and |
| 37 | + flexible coverage computation that relies on a |
| 38 | + memory efficient algorithm and is designed for |
| 39 | + integration in pipelines; this is possible as a |
| 40 | + result of reading alignment files from streams. The |
| 41 | + tools in the suite can process sorted BAM or CRAM |
| 42 | + files, allowing the user to extract coverage |
| 43 | + information via different filtering approaches and |
| 44 | + also save the output in different formats (BED, Wig |
| 45 | + or counts). |
| 46 | +
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| 47 | + The BamToCov algorithm can also handle |
| 48 | + strand-specific and/or physical coverage analyses. |
| 49 | +
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| 50 | +
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| 51 | + Availability: This program, accessory utilities, |
| 52 | + and their documentation are freely available at |
| 53 | + https://github.com/telatin/BamToCov. |
| 54 | +keywords: |
| 55 | + - bioinformatics |
| 56 | + - sequence coverage |
| 57 | + - next-generation sequencing |
| 58 | +license: MIT |
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