diff --git a/pyproject.toml b/pyproject.toml
index 96a17a60c..07b71b71a 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -28,7 +28,7 @@ grpc = ["grpcio>=1.48.2,<2"]
 opentelemetry = ["opentelemetry-api>=1.11.1,<2", "opentelemetry-sdk>=1.11.1,<2"]
 pydantic = ["pydantic>=2.0.0,<3"]
 openai-agents = [
-  "openai-agents>=0.3,<0.4",
+  "openai-agents>=0.3,<0.5",
   "mcp>=1.9.4, <2",
 ]
 
@@ -58,7 +58,7 @@ dev = [
   "pytest-cov>=6.1.1",
   "httpx>=0.28.1",
   "pytest-pretty>=1.3.0",
-  "openai-agents>=0.3,<0.4; python_version >= '3.14'",
+  "openai-agents>=0.3,<0.5; python_version >= '3.14'",
   "openai-agents[litellm]>=0.3,<0.4; python_version < '3.14'",
   "googleapis-common-protos==1.70.0",
 ]
diff --git a/uv.lock b/uv.lock
index df0875606..68f2f73bd 100644
--- a/uv.lock
+++ b/uv.lock
@@ -1311,7 +1311,7 @@ dependencies = [
     { name = "importlib-metadata", marker = "python_full_version < '3.14'" },
     { name = "jinja2", marker = "python_full_version < '3.14'" },
     { name = "jsonschema", marker = "python_full_version < '3.14'" },
-    { name = "openai", marker = "python_full_version < '3.14'" },
+    { name = "openai", version = "1.109.1", source = { registry = "https://pypi.org/simple" }, marker = "python_full_version < '3.14'" },
     { name = "pydantic", marker = "python_full_version < '3.14'" },
     { name = "python-dotenv", marker = "python_full_version < '3.14'" },
     { name = "tiktoken", marker = "python_full_version < '3.14'" },
@@ -1816,33 +1816,61 @@ wheels = [
 name = "openai"
 version = "1.109.1"
 source = { registry = "https://pypi.org/simple" }
+resolution-markers = [
+    "python_full_version < '3.14'",
+]
 dependencies = [
-    { name = "anyio" },
-    { name = "distro" },
-    { name = "httpx" },
-    { name = "jiter" },
-    { name = "pydantic" },
-    { name = "sniffio" },
-    { name = "tqdm" },
-    { name = "typing-extensions" },
+    { name = "anyio", marker = "python_full_version < '3.14'" },
+    { name = "distro", marker = "python_full_version < '3.14'" },
+    { name = "httpx", marker = "python_full_version < '3.14'" },
+    { name = "jiter", marker = "python_full_version < '3.14'" },
+    { name = "pydantic", marker = "python_full_version < '3.14'" },
+    { name = "sniffio", marker = "python_full_version < '3.14'" },
+    { name = "tqdm", marker = "python_full_version < '3.14'" },
+    { name = "typing-extensions", marker = "python_full_version < '3.14'" },
 ]
 sdist = { url = "https://files.pythonhosted.org/packages/c6/a1/a303104dc55fc546a3f6914c842d3da471c64eec92043aef8f652eb6c524/openai-1.109.1.tar.gz", hash = "sha256:d173ed8dbca665892a6db099b4a2dfac624f94d20a93f46eb0b56aae940ed869", size = 564133, upload-time = "2025-09-24T13:00:53.075Z" }
 wheels = [
     { url = "https://files.pythonhosted.org/packages/1d/2a/7dd3d207ec669cacc1f186fd856a0f61dbc255d24f6fdc1a6715d6051b0f/openai-1.109.1-py3-none-any.whl", hash = "sha256:6bcaf57086cf59159b8e27447e4e7dd019db5d29a438072fbd49c290c7e65315", size = 948627, upload-time = "2025-09-24T13:00:50.754Z" },
 ]
 
+[[package]]
+name = "openai"
+version = "2.6.0"
+source = { registry = "https://pypi.org/simple" }
+resolution-markers = [
+    "python_full_version >= '3.14'",
+]
+dependencies = [
+    { name = "anyio", marker = "python_full_version >= '3.14'" },
+    { name = "distro", marker = "python_full_version >= '3.14'" },
+    { name = "httpx", marker = "python_full_version >= '3.14'" },
+    { name = "jiter", marker = "python_full_version >= '3.14'" },
+    { name = "pydantic", marker = "python_full_version >= '3.14'" },
+    { name = "sniffio", marker = "python_full_version >= '3.14'" },
+    { name = "tqdm", marker = "python_full_version >= '3.14'" },
+    { name = "typing-extensions", marker = "python_full_version >= '3.14'" },
+]
+sdist = { url = "https://files.pythonhosted.org/packages/ee/c7/e42bcd89dfd47fec8a30b9e20f93e512efdbfbb3391b05bbb79a2fb295fa/openai-2.6.0.tar.gz", hash = "sha256:f119faf7fc07d7e558c1e7c32c873e241439b01bd7480418234291ee8c8f4b9d", size = 592904, upload-time = "2025-10-20T17:17:24.588Z" }
+wheels = [
+    { url = "https://files.pythonhosted.org/packages/c0/0a/58e9dcd34abe273eaeac3807a8483073767b5609d01bb78ea2f048e515a0/openai-2.6.0-py3-none-any.whl", hash = "sha256:f33fa12070fe347b5787a7861c8dd397786a4a17e1c3186e239338dac7e2e743", size = 1005403, upload-time = "2025-10-20T17:17:22.091Z" },
+]
+
 [[package]]
 name = "openai-agents"
 version = "0.3.3"
 source = { registry = "https://pypi.org/simple" }
+resolution-markers = [
+    "python_full_version < '3.14'",
+]
 dependencies = [
-    { name = "griffe" },
-    { name = "mcp" },
-    { name = "openai" },
-    { name = "pydantic" },
-    { name = "requests" },
-    { name = "types-requests" },
-    { name = "typing-extensions" },
+    { name = "griffe", marker = "python_full_version < '3.14'" },
+    { name = "mcp", marker = "python_full_version < '3.14'" },
+    { name = "openai", version = "1.109.1", source = { registry = "https://pypi.org/simple" }, marker = "python_full_version < '3.14'" },
+    { name = "pydantic", marker = "python_full_version < '3.14'" },
+    { name = "requests", marker = "python_full_version < '3.14'" },
+    { name = "types-requests", marker = "python_full_version < '3.14'" },
+    { name = "typing-extensions", marker = "python_full_version < '3.14'" },
 ]
 sdist = { url = "https://files.pythonhosted.org/packages/a4/37/2b4f828840d3ff32d82b813c3371ec9ee26b3b8dc6b4acbb7a4a579f617a/openai_agents-0.3.3.tar.gz", hash = "sha256:b016381a6890e1cb6879eb23c53c35f8c2312be1117f1cd4e4b5e2463150839f", size = 1816230, upload-time = "2025-09-30T23:20:24.22Z" }
 wheels = [
@@ -1854,6 +1882,27 @@ litellm = [
     { name = "litellm", marker = "python_full_version < '3.14'" },
 ]
 
+[[package]]
+name = "openai-agents"
+version = "0.4.1"
+source = { registry = "https://pypi.org/simple" }
+resolution-markers = [
+    "python_full_version >= '3.14'",
+]
+dependencies = [
+    { name = "griffe", marker = "python_full_version >= '3.14'" },
+    { name = "mcp", marker = "python_full_version >= '3.14'" },
+    { name = "openai", version = "2.6.0", source = { registry = "https://pypi.org/simple" }, marker = "python_full_version >= '3.14'" },
+    { name = "pydantic", marker = "python_full_version >= '3.14'" },
+    { name = "requests", marker = "python_full_version >= '3.14'" },
+    { name = "types-requests", marker = "python_full_version >= '3.14'" },
+    { name = "typing-extensions", marker = "python_full_version >= '3.14'" },
+]
+sdist = { url = "https://files.pythonhosted.org/packages/d2/76/52398d0416706daa69b7e79d1d86f728bea4a49b60442006e397564d1366/openai_agents-0.4.1.tar.gz", hash = "sha256:ead3ad58fd918dd7bcbfcb5cd43a27bcd9dfca1e47f444afcf7b62c86f0f2634", size = 1924077, upload-time = "2025-10-22T00:47:12.799Z" }
+wheels = [
+    { url = "https://files.pythonhosted.org/packages/ee/38/df7ecff75ee67779e5159d0ac34e483ef99e658984b5a0706ccbdd68c1bf/openai_agents-0.4.1-py3-none-any.whl", hash = "sha256:d59fa9545625965b270b4d177b58db013730bf1b8c835b473f1e26ebf78a5eb4", size = 215641, upload-time = "2025-10-22T00:47:10.687Z" },
+]
+
 [[package]]
 name = "opentelemetry-api"
 version = "1.37.0"
@@ -2362,7 +2411,7 @@ name = "python-dateutil"
 version = "2.9.0.post0"
 source = { registry = "https://pypi.org/simple" }
 dependencies = [
-    { name = "six" },
+    { name = "six", marker = "python_full_version < '3.14'" },
 ]
 sdist = { url = "https://files.pythonhosted.org/packages/66/c0/0c8b6ad9f17a802ee498c46e004a0eb49bc148f2fd230864601a86dcf6db/python-dateutil-2.9.0.post0.tar.gz", hash = "sha256:37dd54208da7e1cd875388217d5e00ebd4179249f90fb72437e91a35459a0ad3", size = 342432, upload-time = "2024-03-01T18:36:20.211Z" }
 wheels = [
@@ -2918,7 +2967,8 @@ grpc = [
 ]
 openai-agents = [
     { name = "mcp" },
-    { name = "openai-agents" },
+    { name = "openai-agents", version = "0.3.3", source = { registry = "https://pypi.org/simple" }, marker = "python_full_version < '3.14'" },
+    { name = "openai-agents", version = "0.4.1", source = { registry = "https://pypi.org/simple" }, marker = "python_full_version >= '3.14'" },
 ]
 opentelemetry = [
     { name = "opentelemetry-api" },
@@ -2937,8 +2987,8 @@ dev = [
     { name = "maturin" },
     { name = "mypy" },
     { name = "mypy-protobuf" },
-    { name = "openai-agents" },
-    { name = "openai-agents", extra = ["litellm"], marker = "python_full_version < '3.14'" },
+    { name = "openai-agents", version = "0.3.3", source = { registry = "https://pypi.org/simple" }, extra = ["litellm"], marker = "python_full_version < '3.14'" },
+    { name = "openai-agents", version = "0.4.1", source = { registry = "https://pypi.org/simple" }, marker = "python_full_version >= '3.14'" },
     { name = "psutil" },
     { name = "pydocstyle" },
     { name = "pydoctor" },
@@ -2958,7 +3008,7 @@ requires-dist = [
     { name = "grpcio", marker = "extra == 'grpc'", specifier = ">=1.48.2,<2" },
     { name = "mcp", marker = "extra == 'openai-agents'", specifier = ">=1.9.4,<2" },
     { name = "nexus-rpc", specifier = "==1.1.0" },
-    { name = "openai-agents", marker = "extra == 'openai-agents'", specifier = ">=0.3,<0.4" },
+    { name = "openai-agents", marker = "extra == 'openai-agents'", specifier = ">=0.3,<0.5" },
     { name = "opentelemetry-api", marker = "extra == 'opentelemetry'", specifier = ">=1.11.1,<2" },
     { name = "opentelemetry-sdk", marker = "extra == 'opentelemetry'", specifier = ">=1.11.1,<2" },
     { name = "protobuf", specifier = ">=3.20,<7.0.0" },
@@ -2978,7 +3028,7 @@ dev = [
     { name = "maturin", specifier = ">=1.8.2" },
     { name = "mypy", specifier = "==1.18.2" },
     { name = "mypy-protobuf", specifier = ">=3.3.0,<4" },
-    { name = "openai-agents", marker = "python_full_version >= '3.14'", specifier = ">=0.3,<0.4" },
+    { name = "openai-agents", marker = "python_full_version >= '3.14'", specifier = ">=0.3,<0.5" },
     { name = "openai-agents", extras = ["litellm"], marker = "python_full_version < '3.14'", specifier = ">=0.3,<0.4" },
     { name = "psutil", specifier = ">=5.9.3,<6" },
     { name = "pydocstyle", specifier = ">=6.3.0,<7" },