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Merge pull request #199 from hyanwong/patch-7
Update readme to cite Science paper
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CITATION.cff

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cff-version: 1.2.0
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message: "If you use tsdate in your work, please cite it as below."
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authors:
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- given-names: Anthony Wilder
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family-names: Wohns
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orcid: "https://orcid.org/0000-0001-7353-1177"
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- given-names: Yan
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family-names: Wong
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orcid: "https://orcid.org/0000-0002-3536-6411"
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- given-names: Ben
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family-names: Jeffery
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orcid: "https://orcid.org/0000-0002-1982-6801"
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title: "Tsdate"
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version: 0.1.4
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date-released: 2021-06-30
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url: "https://github.com/tskit-dev/tsdate"
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license: MIT
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preferred-citation:
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type: article
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authors:
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- given-names: Anthony Wilder
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family-names: Wohns
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orcid: "https://orcid.org/0000-0001-7353-1177"
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- given-names: Yan
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family-names: Wong
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orcid: "https://orcid.org/0000-0002-3536-6411"
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- given-names: Ben
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family-names: Jeffery
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orcid: "https://orcid.org/0000-0002-1982-6801"
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- given-names: Ali
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family-names: Akbari
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orcid: "https://orcid.org/0000-0002-5000-5876"
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- given-names: Swapan
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family-names: Mallick
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orcid: "https://orcid.org/0000-0002-4531-4439"
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- given-names: Ron
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family-names: Pinhasi
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orcid: "https://orcid.org/0000-0003-1629-8131"
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- given-names: Nick
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family-names: Patterson
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orcid: "https://orcid.org/0000-0003-0302-684X"
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- given-names: David
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family-names: Reich
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orcid: "https://orcid.org/0000-0002-7037-5292"
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- given-names: Jerome
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family-names: Kelleher
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orcid: "https://orcid.org/0000-0002-7894-5253"
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- given-names: Gil
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family-names: McVean
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orcid: "https://orcid.org/0000-0002-5012-4162"
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doi: "10.1126/science.abi8264"
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journal: "Science"
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start: eabi8264
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title: "A unified genealogy of modern and ancient genomes"
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volume: 375
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year: 2022

README.md

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[![Documentation Status](https://readthedocs.org/projects/tsdate/badge/?version=latest)](https://tsdate.readthedocs.io/en/latest/?badge=latest)
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``tsdate`` is a scalable method for estimating the age of ancestral nodes in a
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[tree sequence](https://www.youtube.com/watch?v=X1GEuQrF1jQ). The method uses a coalescent prior and updates node times on the basis of the number of mutations along each edge of the tree sequence (i.e. using the "molecular clock").
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[tree sequence](https://tskit.dev/tutorials/what_is.html). The method uses a coalescent prior and updates node times on the basis of the number of mutations along each edge of the tree sequence (i.e. using the "molecular clock").
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The method is designed to operate on the output of [tsinfer](https://tsinfer.readthedocs.io/en/latest/), which efficiently infers tree sequence *topologies* from large genetic datasets.
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Please refer to the [documentation](https://tsdate.readthedocs.io/en/latest/) for information on installing and using the software.
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The algorithm is described [in this BioRxiv preprint](https://www.biorxiv.org/content/10.1101/2021.02.16.431497v2). We also provide evaluations of the accuracy and computational requirements of the method using both simulated and real data. The code to reproduce these results can be found in [another repository](https://github.com/awohns/unified_genealogy_paper).
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The algorithm is described [in this Science paper](https://www.science.org/doi/10.1126/science.abi8264) (preprint [here](https://www.biorxiv.org/content/10.1101/2021.02.16.431497v2)). We also provide evaluations of the accuracy and computational requirements of the method using both simulated and real data. The code to reproduce these results can be found in [another repository](https://github.com/awohns/unified_genealogy_paper).
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> Anthony Wilder Wohns, Yan Wong, Ben Jeffery, Ali Akbari, Swapan Mallick, Ron Pinhasi, Nick Patterson, David Reich, Jerome Kelleher, and Gil McVean (2021) _A unified genealogy of modern and ancient genomes_. bioRxiv 2021.02.16.431497; doi: https://doi.org/10.1101/2021.02.16.431497
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> Anthony Wilder Wohns, Yan Wong, Ben Jeffery, Ali Akbari, Swapan Mallick, Ron Pinhasi, Nick Patterson, David Reich, Jerome Kelleher, and Gil McVean (2022) _A unified genealogy of modern and ancient genomes_. Science **375**: eabi8264; doi: https://doi.org/10.1126/science.abi8264
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Please cite this preprint if you use ``tsdate`` in published work.
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Please cite this paper if you use ``tsdate`` in published work.

docs/introduction.rst

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============
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``tsdate`` is a scalable method for estimating the age of ancestral nodes in a
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`tree sequence <https://www.youtube.com/watch?v=X1GEuQrF1jQ>`_. The method uses a coalescent prior and updates node times on the basis of the number of mutations along each edge of the tree sequence (i.e. using the "molecular clock").
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`tree sequence <https://tskit.dev/tutorials/what_is.html>`_. The method uses a coalescent prior and updates node times on the basis of the number of mutations along each edge of the tree sequence (i.e. using the "molecular clock").
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The method is designed to operate on the output of `tsinfer <https://tsinfer.readthedocs.io/en/latest/>`_, which efficiently infers tree sequence *topologies* from large genetic datasets. ``tsdate`` and ``tsinfer`` are scalable to the largest genomic datasets currently available.
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The algorithm is described `in this BioRxiv preprint <https://www.biorxiv.org/content/10.1101/2021.02.16.431497v2>`_. We also provide evaluations of the accuracy and computational requirements of the method using both simulated and real data; the code to reproduce these results can be found in `another repository <https://github.com/awohns/unified_genealogy_paper>`_.
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The algorithm is described `in this Science paper <https://www.science.org/doi/10.1126/science.abi8264>`_
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(preprint `here <https://www.biorxiv.org/content/10.1101/2021.02.16.431497v2>`_). We also provide evaluations of the accuracy and computational requirements of the method using both simulated and real data; the code to reproduce these results can be found in `another repository <https://github.com/awohns/unified_genealogy_paper>`_.
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Please cite this preprint if you use ``tsdate`` in published work:
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Please cite this paper if you use ``tsdate`` in published work:
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> Anthony Wilder Wohns, Yan Wong, Ben Jeffery, Ali Akbari, Swapan Mallick, Ron Pinhasi, Nick Patterson, David Reich, Jerome Kelleher, and Gil McVean (2021) *A unified genealogy of modern and ancient genomes*. bioRxiv 2021.02.16.431497; doi: https://doi.org/10.1101/2021.02.16.431497
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> Anthony Wilder Wohns, Yan Wong, Ben Jeffery, Ali Akbari, Swapan Mallick, Ron Pinhasi, Nick Patterson, David Reich, Jerome Kelleher, and Gil McVean (2022) *A unified genealogy of modern and ancient genomes*. Science **375**: eabi8264; doi: https://doi.org/10.1126/science.abi826421
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docs/requirements.txt

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attrs
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recommonmark
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six
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setuptools_scm
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sphinx-argparse
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tskit
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scipy
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tqdm
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appdirs
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appdirs

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