The largest tuple size for which ScalaCheck provides built-in shrinking is 9. I think ScalaCheck should provide built-in shrinking for all tuple sizes (i.e. 2 to 22).
At work we would like to shrink both 11- and 22-tuples, and they might change size as the underlying case classes acquire new fields. I'll happily do the copy-paste grunt work of writing the patch if you think this is a feature you want.