diff --git a/vllm/config/cache.py b/vllm/config/cache.py
index 3d2496b7f21d..64be80ce3188 100644
--- a/vllm/config/cache.py
+++ b/vllm/config/cache.py
@@ -23,7 +23,7 @@
 
 BlockSize = Literal[1, 8, 16, 32, 64, 128]
 CacheDType = Literal["auto", "bfloat16", "fp8", "fp8_e4m3", "fp8_e5m2", "fp8_inc"]
-MambaDType = Literal["auto", "float32"]
+MambaDType = Literal["auto", "float32", "fp8", "fp8_e4m3"]
 PrefixCachingHashAlgo = Literal["sha256", "sha256_cbor"]
 
 
diff --git a/vllm/model_executor/layers/mamba/mamba_mixer2.py b/vllm/model_executor/layers/mamba/mamba_mixer2.py
index 7589905ac927..d06195dab3ce 100644
--- a/vllm/model_executor/layers/mamba/mamba_mixer2.py
+++ b/vllm/model_executor/layers/mamba/mamba_mixer2.py
@@ -46,6 +46,7 @@
     sharded_weight_loader,
 )
 from vllm.model_executor.utils import set_weight_attrs
+from vllm.platforms import current_platform
 from vllm.utils import direct_register_custom_op
 from vllm.v1.attention.backends.mamba2_attn import Mamba2AttentionMetadata
 
@@ -465,7 +466,7 @@ def __init__(
         compilation_config.static_forward_context[prefix] = self
         # The tuple is (conv_state, ssm_state)
         self.kv_cache = (torch.tensor([]), torch.tensor([]))
-
+        self.fp8_dtype = current_platform.fp8_dtype()
         self.model_config = model_config
         self.cache_config = cache_config
         self.prefix = prefix
@@ -514,7 +515,10 @@ def forward_cuda(
             self_kv_cache = self.kv_cache[forward_context.virtual_engine]
             # conv_state = (..., dim, width-1) yet contiguous along 'dim'
             conv_state = self_kv_cache[0].transpose(-1, -2)
-            ssm_state = self_kv_cache[1]
+            if self.cache_config.mamba_ssm_cache_dtype.startswith("fp8"):
+                ssm_state = self_kv_cache[1].view(self.fp8_dtype)
+            else:
+                ssm_state = self_kv_cache[1]
             state_indices_tensor = attn_metadata.state_indices_tensor
             has_initial_states_p = attn_metadata.has_initial_states_p
             prep_initial_states = attn_metadata.prep_initial_states
@@ -689,6 +693,9 @@ def forward_cuda(
                     0,
                 )
 
+                # TODO: add fp8 dequantization logic here when loading
+                #       ssm state. Should load scales tensors if available
+
             # NOTE: final output is an in-place update of out tensor
             varlen_states = mamba_chunk_scan_combined_varlen(
                 hidden_states_p.view(
@@ -791,6 +798,9 @@ def forward_cuda(
                 #   tensor
                 ssm_state[state_indices_tensor_p] = varlen_states
 
+            # TODO: Add fp8 quantization logic here for storing back
+            #       ssm state. Should also update scales if dynamic
+
         # Process decode requests
         if has_decode:
             if prefix_caching_enabled:
diff --git a/vllm/model_executor/layers/mamba/mamba_utils.py b/vllm/model_executor/layers/mamba/mamba_utils.py
index 21c36617a872..5e323f4d6fa6 100644
--- a/vllm/model_executor/layers/mamba/mamba_utils.py
+++ b/vllm/model_executor/layers/mamba/mamba_utils.py
@@ -51,6 +51,8 @@ def _mamba_state_dtype(
         mamba_cache_dtype: MambaDType,
         mamba_ssm_cache_dtype: MambaDType,
     ) -> tuple[torch.dtype, ...]:
+        if mamba_cache_dtype.startswith("fp8"):
+            raise ValueError("fp8 mamba conv state is not supported")
         conv_state_dtype = get_kv_cache_torch_dtype(mamba_cache_dtype, model_dtype)
         if mamba_ssm_cache_dtype == "auto":
             temporal_state_dtype = conv_state_dtype