diff --git a/packages/runtime-dom/src/directives/vOn.ts b/packages/runtime-dom/src/directives/vOn.ts
index c1a2e182f00..44b7958846d 100644
--- a/packages/runtime-dom/src/directives/vOn.ts
+++ b/packages/runtime-dom/src/directives/vOn.ts
@@ -52,21 +52,24 @@ const modifierGuards: Record<
 export const withModifiers = <
   T extends (event: Event, ...args: unknown[]) => any,
 >(
-  fn: T & { _withMods?: { [key: string]: T } },
+  fn: T & { _withMods?: Map<string, T> },
   modifiers: VOnModifiers[],
 ): T => {
-  const cache = fn._withMods || (fn._withMods = {})
+  const cache = fn._withMods || (fn._withMods = new Map())
   const cacheKey = modifiers.join('.')
-  return (
-    cache[cacheKey] ||
-    (cache[cacheKey] = ((event, ...args) => {
-      for (let i = 0; i < modifiers.length; i++) {
-        const guard = modifierGuards[modifiers[i] as ModifierGuards]
-        if (guard && guard(event, modifiers)) return
-      }
-      return fn(event, ...args)
-    }) as T)
-  )
+  const cached = cache.get(cacheKey)
+  if (cached) {
+    return cached
+  }
+  const modifier = ((event, ...args) => {
+    for (let i = 0; i < modifiers.length; i++) {
+      const guard = modifierGuards[modifiers[i] as ModifierGuards]
+      if (guard && guard(event, modifiers)) return
+    }
+    return fn(event, ...args)
+  }) as T
+  cache.set(cacheKey, modifier)
+  return modifier
 }
 
 // Kept for 2.x compat.
@@ -88,7 +91,7 @@ const keyNames: Record<
  * @private
  */
 export const withKeys = <T extends (event: KeyboardEvent) => any>(
-  fn: T & { _withKeys?: { [k: string]: T } },
+  fn: T & { _withKeys?: Map<string, T> },
   modifiers: string[],
 ): T => {
   let globalKeyCodes: LegacyConfig['keyCodes']
@@ -110,54 +113,60 @@ export const withKeys = <T extends (event: KeyboardEvent) => any>(
     }
   }
 
-  const cache: { [k: string]: T } = fn._withKeys || (fn._withKeys = {})
+  const cache: Map<string, T> = fn._withKeys || (fn._withKeys = new Map())
   const cacheKey = modifiers.join('.')
 
-  return (
-    cache[cacheKey] ||
-    (cache[cacheKey] = (event => {
-      if (!('key' in event)) {
-        return
-      }
+  const cached = cache.get(cacheKey)
+  if (cached) {
+    return cached
+  }
 
-      const eventKey = hyphenate(event.key)
+  const withKey = (event => {
+    if (!('key' in event)) {
+      return
+    }
+
+    const eventKey = hyphenate(event.key)
+    if (
+      modifiers.some(
+        k =>
+          k === eventKey ||
+          keyNames[k as unknown as CompatModifiers] === eventKey,
+      )
+    ) {
+      return fn(event)
+    }
+
+    if (__COMPAT__) {
+      const keyCode = String(event.keyCode)
       if (
-        modifiers.some(
-          k =>
-            k === eventKey ||
-            keyNames[k as unknown as CompatModifiers] === eventKey,
-        )
+        compatUtils.isCompatEnabled(
+          DeprecationTypes.V_ON_KEYCODE_MODIFIER,
+          instance,
+        ) &&
+        modifiers.some(mod => mod == keyCode)
       ) {
         return fn(event)
       }
-
-      if (__COMPAT__) {
-        const keyCode = String(event.keyCode)
-        if (
-          compatUtils.isCompatEnabled(
-            DeprecationTypes.V_ON_KEYCODE_MODIFIER,
-            instance,
-          ) &&
-          modifiers.some(mod => mod == keyCode)
-        ) {
-          return fn(event)
-        }
-        if (globalKeyCodes) {
-          for (const mod of modifiers) {
-            const codes = globalKeyCodes[mod]
-            if (codes) {
-              const matches = isArray(codes)
-                ? codes.some(code => String(code) === keyCode)
-                : String(codes) === keyCode
-              if (matches) {
-                return fn(event)
-              }
+      if (globalKeyCodes) {
+        for (const mod of modifiers) {
+          const codes = globalKeyCodes[mod]
+          if (codes) {
+            const matches = isArray(codes)
+              ? codes.some(code => String(code) === keyCode)
+              : String(codes) === keyCode
+            if (matches) {
+              return fn(event)
             }
           }
         }
       }
-    }) as T)
-  )
+    }
+  }) as T
+
+  cache.set(cacheKey, withKey)
+
+  return withKey
 }
 
 export type VOnDirective = Directive<any, any, VOnModifiers>
diff --git a/packages/runtime-dom/src/modules/style.ts b/packages/runtime-dom/src/modules/style.ts
index 383628a6ad0..380cb766905 100644
--- a/packages/runtime-dom/src/modules/style.ts
+++ b/packages/runtime-dom/src/modules/style.ts
@@ -103,22 +103,24 @@ function setStyle(
 }
 
 const prefixes = ['Webkit', 'Moz', 'ms']
-const prefixCache: Record<string, string> = {}
+const prefixCache: Map<string, string> = new Map()
 
 function autoPrefix(style: CSSStyleDeclaration, rawName: string): string {
-  const cached = prefixCache[rawName]
+  const cached = prefixCache.get(rawName)
   if (cached) {
     return cached
   }
   let name = camelize(rawName)
   if (name !== 'filter' && name in style) {
-    return (prefixCache[rawName] = name)
+    prefixCache.set(rawName, name)
+    return name
   }
   name = capitalize(name)
   for (let i = 0; i < prefixes.length; i++) {
     const prefixed = prefixes[i] + name
     if (prefixed in style) {
-      return (prefixCache[rawName] = prefixed)
+      prefixCache.set(rawName, prefixed)
+      return prefixed
     }
   }
   return rawName
diff --git a/packages/server-renderer/src/helpers/ssrCompile.ts b/packages/server-renderer/src/helpers/ssrCompile.ts
index 8412a65e843..b8223bfd532 100644
--- a/packages/server-renderer/src/helpers/ssrCompile.ts
+++ b/packages/server-renderer/src/helpers/ssrCompile.ts
@@ -17,7 +17,7 @@ type SSRRenderFunction = (
   parentInstance: ComponentInternalInstance,
 ) => void
 
-const compileCache: Record<string, SSRRenderFunction> = Object.create(null)
+const compileCache: Map<string, SSRRenderFunction> = new Map()
 
 export function ssrCompile(
   template: string,
@@ -62,7 +62,7 @@ export function ssrCompile(
     },
   )
 
-  const cached = compileCache[cacheKey]
+  const cached = compileCache.get(cacheKey)
   if (cached) {
     return cached
   }
@@ -89,5 +89,8 @@ export function ssrCompile(
     'vue/server-renderer': helpers,
   }
   const fakeRequire = (id: 'vue' | 'vue/server-renderer') => requireMap[id]
-  return (compileCache[cacheKey] = Function('require', code)(fakeRequire))
+
+  const ssrRenderFunction = Function('require', code)(fakeRequire)
+  compileCache.set(cacheKey, ssrRenderFunction)
+  return ssrRenderFunction
 }
diff --git a/packages/shared/src/domAttrConfig.ts b/packages/shared/src/domAttrConfig.ts
index b5f0166327f..249198ae3a0 100644
--- a/packages/shared/src/domAttrConfig.ts
+++ b/packages/shared/src/domAttrConfig.ts
@@ -34,17 +34,21 @@ export function includeBooleanAttr(value: unknown): boolean {
 }
 
 const unsafeAttrCharRE = /[>/="'\u0009\u000a\u000c\u0020]/
-const attrValidationCache: Record<string, boolean> = {}
+const attrValidationCache: Map<string, boolean> = new Map()
 
 export function isSSRSafeAttrName(name: string): boolean {
-  if (attrValidationCache.hasOwnProperty(name)) {
-    return attrValidationCache[name]
+  const cached = attrValidationCache.get(name)
+  if (cached) {
+    return cached
   }
+
   const isUnsafe = unsafeAttrCharRE.test(name)
   if (isUnsafe) {
     console.error(`unsafe attribute name: ${name}`)
   }
-  return (attrValidationCache[name] = !isUnsafe)
+  attrValidationCache.set(name, !isUnsafe)
+
+  return !isUnsafe
 }
 
 export const propsToAttrMap: Record<string, string | undefined> = {
diff --git a/packages/shared/src/general.ts b/packages/shared/src/general.ts
index 9c6a2313240..c58677c878e 100644
--- a/packages/shared/src/general.ts
+++ b/packages/shared/src/general.ts
@@ -38,14 +38,15 @@ export const hasOwn = (
 
 export const isArray: typeof Array.isArray = Array.isArray
 export const isMap = (val: unknown): val is Map<any, any> =>
-  toTypeString(val) === '[object Map]'
+  !!val && (val as any)[Symbol.toStringTag] === 'Map'
 export const isSet = (val: unknown): val is Set<any> =>
-  toTypeString(val) === '[object Set]'
+  !!val && (val as any)[Symbol.toStringTag] === 'Set'
 
 export const isDate = (val: unknown): val is Date =>
   toTypeString(val) === '[object Date]'
 export const isRegExp = (val: unknown): val is RegExp =>
-  toTypeString(val) === '[object RegExp]'
+  // refer https://262.ecma-international.org/15.0/index.html#sec-isregexp
+  !!val && !!(val as any)[Symbol.match]
 export const isFunction = (val: unknown): val is Function =>
   typeof val === 'function'
 export const isString = (val: unknown): val is string => typeof val === 'string'
@@ -54,11 +55,7 @@ export const isObject = (val: unknown): val is Record<any, any> =>
   val !== null && typeof val === 'object'
 
 export const isPromise = <T = any>(val: unknown): val is Promise<T> => {
-  return (
-    (isObject(val) || isFunction(val)) &&
-    isFunction((val as any).then) &&
-    isFunction((val as any).catch)
-  )
+  return !!val && (val as any)[Symbol.toStringTag] === 'Promise'
 }
 
 export const objectToString: typeof Object.prototype.toString =
@@ -94,10 +91,15 @@ export const isBuiltInDirective: (key: string) => boolean =
   )
 
 const cacheStringFunction = <T extends (str: string) => string>(fn: T): T => {
-  const cache: Record<string, string> = Object.create(null)
+  const cache: Map<string, string> = new Map()
   return ((str: string) => {
-    const hit = cache[str]
-    return hit || (cache[str] = fn(str))
+    const cached = cache.get(str)
+    if (cached) {
+      return cached
+    }
+    const res = fn(str)
+    cache.set(str, res)
+    return res
   }) as T
 }
 
diff --git a/packages/shared/src/makeMap.ts b/packages/shared/src/makeMap.ts
index e85efe21e5b..b1003b3b90f 100644
--- a/packages/shared/src/makeMap.ts
+++ b/packages/shared/src/makeMap.ts
@@ -8,7 +8,6 @@
 
 /*! #__NO_SIDE_EFFECTS__ */
 export function makeMap(str: string): (key: string) => boolean {
-  const map = Object.create(null)
-  for (const key of str.split(',')) map[key] = 1
-  return val => val in map
+  const map = new Set(str.split(','))
+  return val => map.has(val)
 }
diff --git a/packages/vue-compat/src/index.ts b/packages/vue-compat/src/index.ts
index d7e9695d824..879b0796ab6 100644
--- a/packages/vue-compat/src/index.ts
+++ b/packages/vue-compat/src/index.ts
@@ -26,7 +26,7 @@ import {
   warnDeprecation,
 } from '../../runtime-core/src/compat/compatConfig'
 
-const compileCache: Record<string, RenderFunction> = Object.create(null)
+const compileCache: Map<string, RenderFunction> = new Map()
 
 function compileToFunction(
   template: string | HTMLElement,
@@ -42,7 +42,7 @@ function compileToFunction(
   }
 
   const key = genCacheKey(template, options)
-  const cached = compileCache[key]
+  const cached = compileCache.get(key)
   if (cached) {
     return cached
   }
@@ -101,7 +101,8 @@ function compileToFunction(
   // mark the function as runtime compiled
   ;(render as InternalRenderFunction)._rc = true
 
-  return (compileCache[key] = render)
+  compileCache.set(key, render)
+  return render
 }
 
 registerRuntimeCompiler(compileToFunction)
diff --git a/packages/vue/src/index.ts b/packages/vue/src/index.ts
index 785f3fd4bb4..79cc0788b9e 100644
--- a/packages/vue/src/index.ts
+++ b/packages/vue/src/index.ts
@@ -25,7 +25,7 @@ if (__DEV__) {
   initDev()
 }
 
-const compileCache: Record<string, RenderFunction> = Object.create(null)
+const compileCache: Map<string, RenderFunction> = new Map()
 
 function compileToFunction(
   template: string | HTMLElement,
@@ -41,7 +41,7 @@ function compileToFunction(
   }
 
   const key = genCacheKey(template, options)
-  const cached = compileCache[key]
+  const cached = compileCache.get(key)
   if (cached) {
     return cached
   }
@@ -98,7 +98,8 @@ function compileToFunction(
   // mark the function as runtime compiled
   ;(render as InternalRenderFunction)._rc = true
 
-  return (compileCache[key] = render)
+  compileCache.set(key, render)
+  return render
 }
 
 registerRuntimeCompiler(compileToFunction)