diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
index 6f69029..2998d6c 100644
--- a/.github/workflows/tests.yml
+++ b/.github/workflows/tests.yml
@@ -22,7 +22,6 @@ jobs:
         config:
         # [Python version, tox env]
         - ["3.11", "release-check"]
-        - ["3.8", "py38"]
         - ["3.9", "py39"]
         - ["3.10", "py310"]
         - ["3.11", "py311"]
diff --git a/.meta.toml b/.meta.toml
index 9814f9a..14af140 100644
--- a/.meta.toml
+++ b/.meta.toml
@@ -2,7 +2,7 @@
 # https://github.com/zopefoundation/meta/tree/master/config/pure-python
 [meta]
 template = "pure-python"
-commit-id = "d3455844"
+commit-id = "d1a00d25"
 
 [python]
 with-pypy = false
@@ -47,7 +47,7 @@ testenv-additional = [
     "    coverage combine",
     "    coverage html",
     "    coverage report -m --fail-under=100",
-    "depends = py38,py39,py310,py311,py311-datetime,py312,py313,coverage",
+    "depends = py39,py310,py311,py311-datetime,py312,py313,coverage",
     ]
 coverage-command = "pytest --cov=src --cov=tests --cov-report= tests {posargs}"
 coverage-setenv = [
@@ -55,7 +55,7 @@ coverage-setenv = [
     ]
 
 [coverage]
-fail-under = 97.9
+fail-under = 97.3
 
 [isort]
 additional-sources = "{toxinidir}/tests"
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index 7ab398c..92c124c 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -12,10 +12,10 @@ repos:
     - id: autopep8
       args: [--in-place, --aggressive, --aggressive]
   - repo: https://github.com/asottile/pyupgrade
-    rev: v3.17.0
+    rev: v3.19.0
     hooks:
     - id: pyupgrade
-      args: [--py38-plus]
+      args: [--py39-plus]
   - repo: https://github.com/isidentical/teyit
     rev: 0.4.3
     hooks:
diff --git a/CHANGES.rst b/CHANGES.rst
index f2cc8ed..be95822 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -4,6 +4,11 @@ Changes
 7.5 (unreleased)
 ----------------
 
+- Drop support for Python 3.8.
+
+- Update setuptools version pin.
+  (`#292 <https://github.com/zopefoundation/RestrictedPython/issues/292>`_)
+
 
 7.4 (2024-10-09)
 ----------------
diff --git a/docs/conf.py b/docs/conf.py
index 3ea6a2c..eb7dc5e 100644
--- a/docs/conf.py
+++ b/docs/conf.py
@@ -60,9 +60,9 @@
 # built documents.
 #
 # The short X.Y version.
-version = '7.4'
+version = '7.5'
 # The full version, including alpha/beta/rc tags.
-release = '7.4'
+release = '7.5'
 
 # The language for content autogenerated by Sphinx. Refer to documentation
 # for a list of supported languages.
@@ -112,7 +112,6 @@
 # Intersphinx Mapping for Links between different Documentations
 intersphinx_mapping = {
     'python3': ('https://docs.python.org/3', None),
-    'python38': ('https://docs.python.org/3.8', None),
     'python39': ('https://docs.python.org/3.9', None),
     'python310': ('https://docs.python.org/3.10', None),
     'python311': ('https://docs.python.org/3.11', None),
diff --git a/docs/contributing/ast/python3_7.ast b/docs/contributing/ast/python3_7.ast
deleted file mode 100755
index 2f50bf5..0000000
--- a/docs/contributing/ast/python3_7.ast
+++ /dev/null
@@ -1,175 +0,0 @@
--- Python 3.7 AST
--- ASDL's 7 builtin types are:
--- identifier, int, string, bytes, object, singleton, constant
---
--- singleton: None, True or False
--- constant can be None, whereas None means "no value" for object.
-
-module Python version "3.7"
-{
-    mod = Module(stmt* body)
-        | Interactive(stmt* body)
-        | Expression(expr body)
-
-        -- not really an actual node but useful in Jython's typesystem.
-        | Suite(stmt* body)
-
-    stmt = FunctionDef(identifier name,
-                       arguments args,
-                       stmt* body,
-                       expr* decorator_list,
-                       expr? returns)
-         | AsyncFunctionDef(identifier name,
-                            arguments args,
-                            stmt* body,
-                            expr* decorator_list,
-                            expr? returns)
-
-         | ClassDef(identifier name,
-                    expr* bases,
-                    keyword* keywords,
-                    stmt* body,
-                    expr* decorator_list)
-         | Return(expr? value)
-
-         | Delete(expr* targets)
-         | Assign(expr* targets, expr value)
-         | AugAssign(expr target, operator op, expr value)
-         -- 'simple' indicates that we annotate simple name without parens
-         | AnnAssign(expr target, expr annotation, expr? value, int simple)
-
-         -- use 'orelse' because else is a keyword in target languages
-         | For(expr target, expr iter, stmt* body, stmt* orelse)
-         | AsyncFor(expr target, expr iter, stmt* body, stmt* orelse)
-         | While(expr test, stmt* body, stmt* orelse)
-         | If(expr test, stmt* body, stmt* orelse)
-         | With(withitem* items, stmt* body)
-         | AsyncWith(withitem* items, stmt* body)
-
-         | Raise(expr? exc, expr? cause)
-         | Try(stmt* body, excepthandler* handlers, stmt* orelse, stmt* finalbody)
-         | Assert(expr test, expr? msg)
-
-         | Import(alias* names)
-         | ImportFrom(identifier? module, alias* names, int? level)
-
-         | Global(identifier* names)
-         | Nonlocal(identifier* names)
-         | Expr(expr value)
-         | Pass
-         | Break
-         | Continue
-
-         -- XXX Jython will be different
-         -- col_offset is the byte offset in the utf8 string the parser uses
-         attributes (int lineno, int col_offset)
-
-         -- BoolOp() can use left & right?
-    expr = BoolOp(boolop op, expr* values)
-         | BinOp(expr left, operator op, expr right)
-         | UnaryOp(unaryop op, expr operand)
-         | Lambda(arguments args, expr body)
-         | IfExp(expr test, expr body, expr orelse)
-         | Dict(expr* keys, expr* values)
-         | Set(expr* elts)
-         | ListComp(expr elt, comprehension* generators)
-         | SetComp(expr elt, comprehension* generators)
-         | DictComp(expr key, expr value, comprehension* generators)
-         | GeneratorExp(expr elt, comprehension* generators)
-         -- the grammar constrains where yield expressions can occur
-         | Await(expr value)
-         | Yield(expr? value)
-         | YieldFrom(expr value)
-         -- need sequences for compare to distinguish between
-         -- x < 4 < 3 and (x < 4) < 3
-         | Compare(expr left, cmpop* ops, expr* comparators)
-         | Call(expr func,
-                expr* args,
-                keyword* keywords)
-         | Num(object n) -- a number as a PyObject.
-         | Str(string s) -- need to specify raw, unicode, etc?
-         | FormattedValue(expr value, int? conversion, expr? format_spec)
-         | JoinedStr(expr* values)
-         | Bytes(bytes s)
-         | NameConstant(singleton value)
-         | Ellipsis
-         | Constant(constant value)
-
-         -- the following expression can appear in assignment context
-         | Attribute(expr value, identifier attr, expr_context ctx)
-         | Subscript(expr value, slice slice, expr_context ctx)
-         | Starred(expr value, expr_context ctx)
-         | Name(identifier id, expr_context ctx)
-         | List(expr* elts, expr_context ctx)
-         | Tuple(expr* elts, expr_context ctx)
-
-         -- col_offset is the byte offset in the utf8 string the parser uses
-         attributes (int lineno, int col_offset)
-
-    expr_context = Load
-                 | Store
-                 | Del
-                 | AugLoad
-                 | AugStore
-                 | Param
-
-    slice = Slice(expr? lower, expr? upper, expr? step)
-          | ExtSlice(slice* dims)
-          | Index(expr value)
-
-    boolop = And
-           | Or
-
-    operator = Add
-             | Sub
-             | Mult
-             | MatMult
-             | Div
-             | Mod
-             | Pow
-             | LShift
-             | RShift
-             | BitOr
-             | BitXor
-             | BitAnd
-             | FloorDiv
-
-    unaryop = Invert
-            | Not
-            | UAdd
-            | USub
-
-    cmpop = Eq
-          | NotEq
-          | Lt
-          | LtE
-          | Gt
-          | GtE
-          | Is
-          | IsNot
-          | In
-          | NotIn
-
-    comprehension = (expr target, expr iter, expr* ifs, int is_async)
-
-    excepthandler = ExceptHandler(expr? type, identifier? name, stmt* body)
-                    attributes (int lineno, int col_offset)
-
-    arguments = (arg* args,
-                 arg? vararg,
-                 arg* kwonlyargs,
-                 expr* kw_defaults,
-                 arg? kwarg,
-                 expr* defaults)
-
-    arg = (identifier arg, expr? annotation)
-          attributes (int lineno, int col_offset)
-
-    -- keyword arguments supplied to call (NULL identifier for **kwargs)
-    keyword = (identifier? arg, expr value)
-
-    -- import name with optional 'as' alias.
-    alias = (identifier name, identifier? asname)
-
-    withitem = (expr context_expr, expr? optional_vars)
-}
diff --git a/docs/contributing/changes_from37to38.rst b/docs/contributing/changes_from37to38.rst
deleted file mode 100644
index 6ece5d5..0000000
--- a/docs/contributing/changes_from37to38.rst
+++ /dev/null
@@ -1,5 +0,0 @@
-Changes from Python 3.7 to Python 3.8
--------------------------------------
-
-.. literalinclude:: ast/python3_8.ast
-   :diff: ast/python3_7.ast
diff --git a/docs/contributing/index.rst b/docs/contributing/index.rst
index c9eef77..23e93b2 100644
--- a/docs/contributing/index.rst
+++ b/docs/contributing/index.rst
@@ -98,7 +98,6 @@ A (modified style) Copy of all Abstract Grammar Definitions for the Python versi
 .. toctree::
    :maxdepth: 2
 
-   changes_from37to38
    changes_from38to39
    changes_from39to310
    changes_from310to311
@@ -236,12 +235,11 @@ Technical Backgrounds - Links to External Documentation
 
   * AST Grammar of Python (`Status of Python Versions`_)
 
+    * `Python 3.13 AST`_ (EOL 2029-10)
     * `Python 3.12 AST`_ (EOL 2028-10)
     * `Python 3.11 AST`_ (EOL 2027-10)
     * `Python 3.10 AST`_ (EOL 2026-10)
     * `Python 3.9 AST`_ (EOL 2025-10)
-    * `Python 3.8 AST`_ (EOL 2024-10)
-    * `Python 3.7 AST`_ (EOL 2023-06-27)
 
   * `AST NodeVistiors Class`_
   * `AST NodeTransformer Class`_
@@ -259,6 +257,8 @@ Todos
 
 .. _`What's new in Python`: https://docs.python.org/3/whatsnew/
 
+.. _`What's new in Python 3.13`: https://docs.python.org/3.13/whatsnew/3.13.html
+
 .. _`What's new in Python 3.12`: https://docs.python.org/3.12/whatsnew/3.12.html
 
 .. _`What's new in Python 3.11`: https://docs.python.org/3.11/whatsnew/3.11.html
@@ -267,10 +267,6 @@ Todos
 
 .. _`What's new in Python 3.9`: https://docs.python.org/3.9/whatsnew/3.9.html
 
-.. _`What's new in Python 3.8`: https://docs.python.org/3.8/whatsnew/3.8.html
-
-.. _`What's new in Python 3.7`: https://docs.python.org/3.7/whatsnew/3.7.html
-
 .. _`Status of Python Versions`: https://devguide.python.org/versions/
 
 .. _`Concept of Immutable Types and Python Example`: https://en.wikipedia.org/wiki/Immutable_object#Python
@@ -285,6 +281,8 @@ Todos
 
 .. _`Python 3 AST`: https://docs.python.org/3/library/ast.html#abstract-grammar
 
+.. _`Python 3.13 AST`: https://docs.python.org/3.13/library/ast.html#abstract-grammar
+
 .. _`Python 3.12 AST`: https://docs.python.org/3.12/library/ast.html#abstract-grammar
 
 .. _`Python 3.11 AST`: https://docs.python.org/3.11/library/ast.html#abstract-grammar
@@ -293,10 +291,6 @@ Todos
 
 .. _`Python 3.9 AST`: https://docs.python.org/3.9/library/ast.html#abstract-grammar
 
-.. _`Python 3.8 AST`: https://docs.python.org/3.8/library/ast.html#abstract-grammar
-
-.. _`Python 3.7 AST`: https://docs.python.org/3.7/library/ast.html#abstract-grammar
-
 .. _`AST NodeVistiors Class`: https://docs.python.org/3/library/ast.html#ast.NodeVisitor
 
 .. _`AST NodeTransformer Class`: https://docs.python.org/3/library/ast.html#ast.NodeTransformer
diff --git a/docs/index.rst b/docs/index.rst
index 7e77a28..b26687c 100644
--- a/docs/index.rst
+++ b/docs/index.rst
@@ -15,7 +15,7 @@ RestrictedPython is not a sandbox system or a secured environment, but it helps
 Supported Python versions
 =========================
 
-RestrictedPython supports CPython 3.7 up to 3.12.
+RestrictedPython supports CPython 3.9 up to 3.13.
 It does _not_ support PyPy or other alternative Python implementations.
 
 Contents
diff --git a/pyproject.toml b/pyproject.toml
index 75267ab..98d77a2 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -3,7 +3,7 @@
 # https://github.com/zopefoundation/meta/tree/master/config/pure-python
 
 [build-system]
-requires = ["setuptools<74"]
+requires = ["setuptools <= 75.6.0"]
 build-backend = "setuptools.build_meta"
 
 [tool.coverage.run]
@@ -11,7 +11,7 @@ branch = true
 source = ["RestrictedPython"]
 
 [tool.coverage.report]
-fail_under = 97.9
+fail_under = 97.3
 precision = 2
 ignore_errors = true
 show_missing = true
diff --git a/setup.py b/setup.py
index 8c87cc1..9452de2 100644
--- a/setup.py
+++ b/setup.py
@@ -39,7 +39,6 @@ def read(*rnames):
           'Programming Language :: Python',
           'Operating System :: OS Independent',
           'Programming Language :: Python :: 3',
-          'Programming Language :: Python :: 3.8',
           'Programming Language :: Python :: 3.9',
           'Programming Language :: Python :: 3.10',
           'Programming Language :: Python :: 3.11',
@@ -60,7 +59,7 @@ def read(*rnames):
       packages=find_packages('src'),
       package_dir={'': 'src'},
       install_requires=[],
-      python_requires=">=3.8, <3.14",
+      python_requires=">=3.9, <3.14",
       extras_require={
           'test': ['pytest', 'pytest-mock'],
           'docs': ['Sphinx', 'furo'],
diff --git a/tox.ini b/tox.ini
index 171abb2..7a093d9 100644
--- a/tox.ini
+++ b/tox.ini
@@ -5,7 +5,6 @@ minversion = 3.18
 envlist =
     release-check
     lint
-    py38
     py39
     py310
     py311
@@ -21,7 +20,7 @@ usedevelop = true
 package = wheel
 wheel_build_env = .pkg
 deps =
-    setuptools  <74
+    setuptools <= 75.6.0
     datetime: DateTime
     -cconstraints.txt
     pytest-cov
@@ -50,7 +49,7 @@ commands =
     coverage combine
     coverage html
     coverage report -m --fail-under=100
-depends = py38,py39,py310,py311,py311-datetime,py312,py313,coverage
+depends = py39,py310,py311,py311-datetime,py312,py313,coverage
 
 [testenv:setuptools-latest]
 basepython = python3
@@ -65,7 +64,7 @@ description = ensure that the distribution is ready to release
 basepython = python3
 skip_install = true
 deps =
-    setuptools <74
+    setuptools <= 75.6.0
     twine
     build
     check-manifest