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    • Hatch plugin for generating Python files from Protocol Buffers .proto files
      Python
      Other
      51410Updated Aug 25, 2026Aug 25, 2026
    • Pod5: a high performance file format for nanopore reads.
      C++
      Other
      41176443Updated Aug 24, 2026Aug 24, 2026
    • dorado

      Public
      Oxford Nanopore's Basecaller
      C++
      Other
      127863894Updated Jul 30, 2026Jul 30, 2026
    • Protobuf and gRPC specifications for the MinKNOW API
      Python
      Other
      1672442Updated Jul 22, 2026Jul 22, 2026
    • Cross platform builds for minimap2
      CMake
      3800Updated Jul 15, 2026Jul 15, 2026
    • modkit

      Public
      A bioinformatics tool for working with modified bases
      Rust
      Other
      3027230022Updated Jul 14, 2026Jul 14, 2026
    • pomoxis

      Public
      Analysis components from Oxford Nanopore Research
      Python
      Other
      2299101Updated Jul 1, 2026Jul 1, 2026
    • medaka

      Public
      Sequence correction provided by ONT Research
      Python
      Other
      90520283Updated May 20, 2026May 20, 2026
    • rerio

      Public
      Research release basecalling models and configurations
      Python
      Other
      1112051Updated May 20, 2026May 20, 2026
    • Specifications for output files from MinKNOW, dorado and others
      Python
      0600Updated Mar 18, 2026Mar 18, 2026
    • bonito

      Public
      A PyTorch Basecaller for Oxford Nanopore Reads
      Python
      Other
      14243642Updated Feb 20, 2026Feb 20, 2026
    • pyspoa

      Public
      Python bindings to spoa
      Python
      Other
      42240Updated Dec 3, 2025Dec 3, 2025
    • pomfret

      Public
      C
      32721Updated Nov 14, 2025Nov 14, 2025
    • Dorado Documentation
      Python
      Other
      1700Updated Aug 4, 2025Aug 4, 2025
    • A curated list of awesome nanopore analysis tools.
      MIT License
      62000Updated Jul 2, 2025Jul 2, 2025
    • Python
      Other
      41471Updated May 2, 2025May 2, 2025
    • VBZ compression plugin for nanopore signal data
      C++
      Mozilla Public License 2.0
      1344211Updated Apr 7, 2025Apr 7, 2025
    • Homebrew casks for applications from Oxford Nanopore Technologies PLC and Metrichor Ltd.
      Ruby
      0700Updated Dec 24, 2024Dec 24, 2024
    • Read Until client library for Nanopore Sequencing
      Python
      Other
      1210800Updated Sep 25, 2024Sep 25, 2024
    • remora

      Public
      Methylation/modified base calling separated from basecalling.
      Python
      Other
      29188171Updated Sep 17, 2024Sep 17, 2024
    • sqlpad

      Public
      Web-based SQL editor run in your own private cloud. Supports MySQL, Postgres, SQL Server, Vertica, Crate, ClickHouse, Trino, Presto, SAP HANA, Cassandra, Snowfl…
      JavaScript
      MIT License
      819000Updated May 14, 2024May 14, 2024
    • Python
      Mozilla Public License 2.0
      61821Updated Mar 11, 2024Mar 11, 2024
    • Oxford Nanopore Technologies fast5 API software
      Python
      Other
      31155132Updated Feb 27, 2024Feb 27, 2024
    • Workflow to prepare high accuracy single molecule consensus sequences from amplicon data using unique molecular identifiers
      Python
      Other
      1435183Updated Feb 27, 2024Feb 27, 2024
    • ONT fork of Linux for NVIDIA Tegra based devices
      C
      Other
      1000Updated Jun 30, 2023Jun 30, 2023
    • Predictive kmer models for development use
      Mozilla Public License 2.0
      206400Updated Jun 6, 2023Jun 6, 2023
    • Splitting of sequence reads by internal adapter sequence search
      Python
      Other
      851210Updated May 30, 2023May 30, 2023
    • megalodon

      Public
      Megalodon is a research command line tool to extract high accuracy modified base and sequence variant calls from raw nanopore reads by anchoring the informatio…
      Python
      Other
      27205470Updated May 4, 2023May 4, 2023
    • tombo

      Public
      Tombo is a suite of tools primarily for the identification of modified nucleotides from raw nanopore sequencing data.
      Python
      Other
      552321332Updated May 4, 2023May 4, 2023
    • Apache License 2.0
      0000Updated Apr 21, 2023Apr 21, 2023
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