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verticox+

This repository contains the components for running vertical cox proportional hazards analysis in a setting where the data is vertically partitioned.

Our solution Verticox+[1] is based on the Verticox algorithm by Dai et al. [2]. It has been adapted to be used within the Vantage6 framework.

This solution is extended with the scalar vector product protocol to remove the requirement that outcome data needs to be available at all parties.

References

  • [1] van Daalen, F., Smits, D., Ippel, L. et al. Verticox+: vertically distributed Cox proportional hazards model with improved privacy guarantees. Complex Intell. Syst. 11, 388 (2025), https://doi.org/10.1007/s40747-025-02022-4
  • [2] W. Dai, X. Jiang, L. Bonomi, Y. Li, H. Xiong and L. Ohno-Machado, "VERTICOX: Vertically Distributed Cox Proportional Hazards Model Using the Alternating Direction Method of Multipliers," in IEEE Transactions on Knowledge and Data Engineering, vol. 34, no. 2, pp. 996-1010, 1 Feb. 2022, doi: https://10.1109/TKDE.2020.2989301.