Welcome to the Epigenetics and Human Disease Laboratory – where we investigate how epigenetic mechanisms regulate gene expression and contribute to human health and disease.

Epigenetics is known as the "science of change", studying how genes are turned on or off without altering the DNA sequence. Everyday factors such as exercise, nutrition, and sleep can lead to chemical modifications that affect gene activity. Unlike genetic mutations, epigenetic changes (epimutations) are reversible, making them promising therapeutic targets.

We aim to:

• Analyze epigenetic signatures in human tissues and cells.
• Investigate their role in aging, cancer development, and multiorgan dysfunction syndromes.
• Translate our findings into diagnostic and prognostic tools.
• Contribute to personalized medicine by identifying new therapeutic strategies.

Our research combines basic science with a strong clinical association, focusing primarily on human cancer and sepsis.

Our GitHub organization hosts a range of open scientific resources, including:

• Data processing and analysis pipelines
• Computational tools for epigenetic research
• Scripts and software used in our publications