Genomic Landscape and Preclinical Therapeutic Insights Developed from Xenograft, Organoid, and Cell Line Models in the NCI’s Patient-Derived Models Repository
Biswajit Das*§, Li Chen*, Yvonne A. Evrard*, Ting-Chia Chang*, Peter I-Fan Wu*, et al.
§Corresponding author: Biswajit Das
These authors contributed equally to this work
Email: dasbiswa@mail.nih.gov
Nature Cancer (2025) [link]
This Github repository contains scripts, figures and configurations to process next‑generation sequencing (NGS) data for the PDMR Landscape project.
https://dctd.cancer.gov/drug-discovery-development/reagents-materials/pdmr
- Web portal for raw data in PDMR (https://pdmdb.cancer.gov/web/apex/f?p=101:41)
- cBioPortal instance (https://www.cbioportal.org/study/summary?id=pancan_pdmr_2025)
- FigShare (https://figshare.com/s/a47ea87939355f7cc558)
- DATA/ folder
- Scripts/ folder
- ngs_pipline/ folder