Enhance README with overview and inventor details

Expanded README with detailed overview and scientific context.

Author: geopayme

README.md

@@ -1,9 +1,33 @@
-# Tri-Modal-Catheter-Lock-TCL
-Tri-Modal Antifungal Catheter Lock (TCL): Proof of Invention Record
+# Tri-Modal-Catheter-Lock-TCL  
+**Tri-Modal Antifungal Catheter Lock (TCL): Proof of Invention Record**
 
-## License
+---
 
-- Documentation, LaTeX sources, figures, and PDFs: **Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)**  
-- Commercial use, manufacturing, or distribution requires prior written authorization.  
-  Please contact **[email protected]** for licensing inquiries.
+## 📘 Overview
+
+This repository contains the public disclosure and LaTeX documentation for the **Tri-Modal Antifungal Catheter Lock (TCL)** —  
+a novel, non-systemic antimicrobial lock formulation designed to eradicate *Candidozyma (Candida) auris* and other resistant fungal biofilms from indwelling medical devices.
+
+The formulation integrates **three synergistic components**:
+1. **Echinocandin antifungal** (e.g., micafungin)
+2. **β-1,3-glucanase enzyme** (for extracellular matrix digestion)
+3. **Gallium(III)/EDTA complex** (for iron substitution and metabolic disruption)
+
+Together, these mechanisms collapse the biofilm matrix, inhibit cell-wall synthesis, and block iron metabolism — achieving ≥3-log CFU reduction without damaging catheter materials.
+
+---
+
+## 🧪 Scientific Context
+
+- **Inventor:** Antonios Valamontes  
+- **Affiliation:** Kapodistrian Academy of Science  
+- **Collaborating Witness:** Dr. Ioannis Adamopoulos — Public Health and Environmental Inspector,  
+  Department of Environmental Hygiene and Public Health Inspections, Region of Attica, Hellenic Republic.  
+- **Contact:** [[email protected]](mailto:[email protected])
+
+This repository serves as an official timestamped record of invention for open scientific disclosure and non-commercial academic collaboration.
+
+---
+
+## 🧩 Repository Structure