Powershell.exe script to move cursor to center of te main screen. Add shortcut key in shortcut to run and place on desktop.
After install whenever you press Ctrl+Shift+Q, your cursor will return home.
Save this script (mousecenter.ps1) in a convenient folder (C:\Program Files\MouseCenter\)
Create a shortcut on your desktop: (or copy the shortcut)
Target: %systemroot%\system32\windowspowershell\v1.0\powershell.exe -ExecutionPolicy RemoteSigned -File "C:\Program Files\MouseCenter\mousecenter.ps1"
Shortcut key: Ctrl + Shift + Q
Run: Minimized