+* If you want to configure a secondary location for your APIM, the VNET and subnet region should match with the secondary location you're configuring. If you're adding, removing, or enabling the Availability zone in the Primary region, or if you're changing the subnet of the primary region, then the VIP of APIM will change. For more information, see [IP addresses of Azure API Management service](/azure/api-management/api-management-howto-ip-addresses#changes-to-the-ip-addresses). However, if you're adding a secondary region, the primary region's VIP of APIM won't change because every region has its own private VIP.
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