@@ -18,7 +18,7 @@ You can also submit changes using the GitHub issue tracker.
1818| PMID| DOI| First author| Year| Type| Molecule| Model| Selection Type| Mutagenesis Type| Sequencing Platform| Raw Data| Scores in Table|
1919| ---| ---| ---| ---| ---| ---| ---| ---| ---| ---| ---| ---|
2020| [ 19915551] ( https://www.ncbi.nlm.nih.gov/pubmed/19915551 ) | [ 10.1038/nbt.1589] ( https://doi.org/10.1038/nbt.1589 ) | Patwardhan| 2009| MPRA| T3 promoter, T7 promoter, SP6 promoter, CMV promoter, HBB promoter, S100A4 promoter| in vitro| Transcription| microarray synthesis| Illumina| [ SRP001721] ( https://www.ebi.ac.uk/ena/data/view/SRP001721 ) | TXT|
21- | [ 20439748] ( https://www.ncbi.nlm.nih.gov/pubmed/20439748 ) | [ 10.1073/pnas.1004290107] ( https://doi.org/10.1073/pnas.1004290107 ) | Kinney| 2010| MPRA| lac promoter| E.coli| FACS| Cassette ligation | Roche 454| [ SRA012345] ( https://www.ebi.ac.uk/ena/data/view/SRA012345 ) | No|
21+ | [ 20439748] ( https://www.ncbi.nlm.nih.gov/pubmed/20439748 ) | [ 10.1073/pnas.1004290107] ( https://doi.org/10.1073/pnas.1004290107 ) | Kinney| 2010| MPRA| lac promoter| E.coli| FACS| doped oligo synthesis | Roche 454| [ SRA012345] ( https://www.ebi.ac.uk/ena/data/view/SRA012345 ) | No|
2222| [ 20711194] ( https://www.ncbi.nlm.nih.gov/pubmed/20711194 ) | [ 10.1038/nmeth.1492] ( https://doi.org/10.1038/nmeth.1492 ) | Fowler| 2010| DMS| WW domain| Phage| Binding| doped oligo synthesis| Illumina| [ SRP002725] ( https://www.ebi.ac.uk/ena/data/view/SRP002725 ) | No|
2323| [ 20714644] ( https://www.ncbi.nlm.nih.gov/pubmed/20714644 ) | [ 10.1039/c0mb00061b] ( https://doi.org/10.1039/c0mb00061b ) | Ernst| 2010| DMS| Synthetic PDZ domain| Phage| Binding| Kunkel| Roche 454| No| No|
2424| [ 21464309] ( https://www.ncbi.nlm.nih.gov/pubmed/21464309 ) | [ 10.1073/pnas.1016024108] ( https://doi.org/10.1073/pnas.1016024108 ) | Hietpas| 2011| DMS| Hsp90| Yeast| Growth| NNN PCR| Illumina| No| TXT|
@@ -33,7 +33,7 @@ You can also submit changes using the GitHub issue tracker.
3333| [ 23017428] ( https://www.ncbi.nlm.nih.gov/pubmed/23017428 ) | [ 10.1016/j.jmb.2012.09.014] ( https://doi.org/10.1016/j.jmb.2012.09.014 ) | Deng| 2012| DMS| TEM1 Beta-lactamase| E.coli| Amp resistance| NNS Kunkel| Roche 454| No| XLS|
3434| [ 23035249] ( https://www.ncbi.nlm.nih.gov/pubmed/23035249 ) | [ 10.1073/pnas.1209751109] ( https://doi.org/10.1073/pnas.1209751109 ) | Araya| 2012| DMS| WW domain| Phage| Binding| doped oligo synthesis| Illumina| Yes| No|
3535| [ 23041932] ( https://www.ncbi.nlm.nih.gov/pubmed/23041932 ) | [ 10.1038/nature11500] ( https://doi.org/10.1038/nature11500 ) | McLaughlin| 2012| DMS| PSD95 PDZ| Bacteria| Special| NNS PCR| Illumina| No| No|
36- | [ 23103372] ( https://www.ncbi.nlm.nih.gov/pubmed/23103372 ) | [ 10.1016/j.bbrc.2012.10.066] ( https://doi.org/10.1016/j.bbrc.2012.10.066 ) | Fujino| 2012| DMS| Fab antibody fragment| in vitro| Ribodisplay| PCR with “fragments”| Roche 454| No| No|
36+ | [ 23103372] ( https://www.ncbi.nlm.nih.gov/pubmed/23103372 ) | [ 10.1016/j.bbrc.2012.10.066] ( https://doi.org/10.1016/j.bbrc.2012.10.066 ) | Fujino| 2012| DMS| Fab antibody fragment| in vitro| Ribodisplay| PCR with “fragments”| Roche 454| No| No|
3737| [ 23152521] ( https://www.ncbi.nlm.nih.gov/pubmed/23152521 ) | [ 10.1128/JVI.01658-12] ( https://doi.org/10.1128/JVI.01658-12 ) | Wu| 2012| DMS| Neuraminidase| Human/H1N1| Oseltamivir resistance| error prone pcr| Roche 454| No| No|
3838| [ 23241746] ( https://www.ncbi.nlm.nih.gov/pubmed/23241746 ) | [ 10.1101/gr.144659.112] ( https://doi.org/10.1101/gr.144659.112 ) | Liachko| 2012| MPRA| Autonomously replicating sequences| Yeast| Growth| doped oligo synthesis| Illumina| [ SRA051406] ( https://www.ebi.ac.uk/ena/data/view/SRA051406 ) | No|
3939| [ 23287719] ( https://www.ncbi.nlm.nih.gov/pubmed/23287719 ) | [ 10.1126/science.1230161] ( https://doi.org/10.1126/science.1230161 ) | Ernst| 2013| DMS| Ubiquitin| Phage| Binding| site-directed mutagenesis with doped oligos| ELISA| No| No|
@@ -78,7 +78,7 @@ You can also submit changes using the GitHub issue tracker.
7878| [ 25657251] ( https://www.ncbi.nlm.nih.gov/pubmed/25657251 ) | [ 10.1126/science.1257360] ( https://doi.org/10.1126/science.1257360 ) | Podgornaia| 2015| DMS| PhoQ| Bacteria| FACS| NNS PCR| Illumina| No| No|
7979| [ 25723163] ( https://www.ncbi.nlm.nih.gov/pubmed/25723163 ) | [ 10.1016/j.cell.2015.01.035] ( https://doi.org/10.1016/j.cell.2015.01.035 ) | Stiffler| 2016| DMS| TEM1 B-lactamase| E.coli| Growth| NNS PCR| Illumina| No| XLS|
8080| [ 25823446] ( https://www.ncbi.nlm.nih.gov/pubmed/25823446 ) | [ 10.1534/genetics.115.175802] ( https://doi.org/10.1534/genetics.115.175802 ) | Starita| 2015| DMS| BRCA1| Yeast, Phage| Growth, Binding| microarray synthesis| Illumina (barcoded and subassembly)| No| XLS|
81- | [ 25875337] ( https://www.ncbi.nlm.nih.gov/pubmed/25875337 ) | [ 10.1371/journal.pgen.1005147] ( https://doi.org/10.1371/journal.pgen.1005147 ) | Shalem| 2015| MPRA| 3’ UTR| Yeast| Fluorescence, Transcription| microarray synthesis| Illumina| No| XLS|
81+ | [ 25875337] ( https://www.ncbi.nlm.nih.gov/pubmed/25875337 ) | [ 10.1371/journal.pgen.1005147] ( https://doi.org/10.1371/journal.pgen.1005147 ) | Shalem| 2015| MPRA| 3’ UTR| Yeast| Fluorescence, Transcription| microarray synthesis| Illumina| No| XLS|
8282| [ 26040002] ( https://www.ncbi.nlm.nih.gov/pubmed/26040002 ) | [ 10.1073/pnas.1422285112] ( https://doi.org/10.1073/pnas.1422285112 ) | Romero| 2015| DMS| Bgl2| Bacteria/microfluidic droplets| Activity| error-prone PCR| Illumina| No| No|
8383| [ 26132554] ( https://www.ncbi.nlm.nih.gov/pubmed/26132554 ) | [ 10.1371/journal.pgen.1005310] ( https://doi.org/10.1371/journal.pgen.1005310 ) | Wu| 2015| DMS| Polymerase PA| Influenza| Growth| error-prone PCR| Illumina| [ PRJNA254185] ( https://www.ebi.ac.uk/ena/data/view/PRJNA254185 ) | XLS|
8484| [ 26170332] ( https://www.ncbi.nlm.nih.gov/pubmed/26170332 ) | [ 10.1073/pnas.1511328112] ( https://doi.org/10.1073/pnas.1511328112 ) | Kretz| 2015| DMS| VWF| Phage| Binding/cleavage| doped oligo synthesis| Illumina| No| XLS|
@@ -179,7 +179,7 @@ You can also submit changes using the GitHub issue tracker.
179179| [ 30778069] ( https://www.ncbi.nlm.nih.gov/pubmed/30778069 ) | [ 10.1038/s41467-019-08777-y] ( https://doi.org/10.1038/s41467-019-08777-y ) | Michaels| 2019| MPRA| microRNA| HEK293T| polysome profiling| degenerate oligos| Illumina| [ PRJNA516224] ( https://www.ebi.ac.uk/ena/data/view/PRJNA516224 ) | No|
180180| [ 30936490] ( https://www.ncbi.nlm.nih.gov/pubmed/30936490 ) | [ 10.1038/s41564-019-0412-y] ( https://doi.org/10.1038/s41564-019-0412-y ) | Noda-Garcia| 2019| DMS| GDH| Bacteria| Growth| NNS PCR| Illumina| No| XLS|
181181| [ 30956043] ( https://www.ncbi.nlm.nih.gov/pubmed/30956043 ) | [ 10.1016/j.molcel.2019.02.003] ( https://doi.org/10.1016/j.molcel.2019.02.003 ) | Ahler| 2019| DMS| Src| Yeast| Growth| NNK PCR| Illumina (barcoded and subassembly)| GSE114098| XLS|
182- | [ 31267113] ( https://www.ncbi.nlm.nih.gov/pubmed/31267113 ) | [ 10.1038/s41587-019-0164-5] ( https://doi.org/10.1038/s41587-019-0164-5 ) | Sample| 2019| MPRA| 5’ UTR| human cells| polysome profiling| random bases| Illumina| GSE114002| No|
182+ | [ 31267113] ( https://www.ncbi.nlm.nih.gov/pubmed/31267113 ) | [ 10.1038/s41587-019-0164-5] ( https://doi.org/10.1038/s41587-019-0164-5 ) | Sample| 2019| MPRA| 5’ UTR| human cells| polysome profiling| random bases| Illumina| GSE114002| No|
183183| [ 31395865] ( https://www.ncbi.nlm.nih.gov/pubmed/31395865 ) | [ 10.1038/s41467-019-11526-w] ( https://doi.org/10.1038/s41467-019-11526-w ) | Kircher| 2019| MPRA| Multiple mammalian promoters and enhancers| multiple cell lines| Transcription| error-prone PCR| Illumina| GSE126550 | TXT|
184184| [ 31697803] ( https://www.ncbi.nlm.nih.gov/pubmed/31697803 ) | [ 10.1182/blood.2019002561 ] ( https://doi.org/10.1182/blood.2019002561 ) | Bridgford| 2020| DMS| MPL| Ba/F3 cells| Growth| NNN PCR| Illlumina| [ SRR10193506] ( https://www.ebi.ac.uk/ena/data/view/SRR10193506 ) | TXT|
185185| [ 32385156] ( https://www.ncbi.nlm.nih.gov/pubmed/32385156 ) | [ 10.1073/pnas.1918680117 ] ( https://doi.org/10.1073/pnas.1918680117 ) | Mehlhoff| 2020| DMS| TEM-1 BL| E.coli| Growth| NNN PCR| Illlumina| PRJNA565437 | XLS|
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