11PMID DOI First author Year Type Molecule Model Selection Type Mutagenesis Type Sequencing Platform Raw Data Scores in Table
2219915551 10.1038/nbt.1589 Patwardhan 2009 MPRA T3 promoter, T7 promoter, SP6 promoter, CMV promoter, HBB promoter, S100A4 promoter in vitro Transcription microarray synthesis Illumina SRP001721 TXT
3- 20439748 10.1073/pnas.1004290107 Kinney 2010 MPRA lac promoter E.coli FACS Cassette ligation Roche 454 SRA012345 No
3+ 20439748 10.1073/pnas.1004290107 Kinney 2010 MPRA lac promoter E.coli FACS doped oligo synthesis Roche 454 SRA012345 No
4420711194 10.1038/nmeth.1492 Fowler 2010 DMS WW domain Phage Binding doped oligo synthesis Illumina SRP002725 No
5520714644 10.1039/c0mb00061b Ernst 2010 DMS Synthetic PDZ domain Phage Binding Kunkel Roche 454 No No
6621464309 10.1073/pnas.1016024108 Hietpas 2011 DMS Hsp90 Yeast Growth NNN PCR Illumina No TXT
@@ -15,7 +15,7 @@ PMID DOI First author Year Type Molecule Model Selection Type Mutagenesis Type S
151523017428 10.1016/j.jmb.2012.09.014 Deng 2012 DMS TEM1 Beta-lactamase E.coli Amp resistance NNS Kunkel Roche 454 No XLS
161623035249 10.1073/pnas.1209751109 Araya 2012 DMS WW domain Phage Binding doped oligo synthesis Illumina Yes No
171723041932 10.1038/nature11500 McLaughlin 2012 DMS PSD95 PDZ Bacteria Special NNS PCR Illumina No No
18- 23103372 10.1016/j.bbrc.2012.10.066 Fujino 2012 DMS Fab antibody fragment in vitro Ribodisplay PCR with “fragments” Roche 454 No No
18+ 23103372 10.1016/j.bbrc.2012.10.066 Fujino 2012 DMS Fab antibody fragment in vitro Ribodisplay PCR with “fragments” Roche 454 No No
191923152521 10.1128/JVI.01658-12 Wu 2012 DMS Neuraminidase Human/H1N1 Oseltamivir resistance error prone pcr Roche 454 No No
202023241746 10.1101/gr.144659.112 Liachko 2012 MPRA Autonomously replicating sequences Yeast Growth doped oligo synthesis Illumina SRA051406 No
212123287719 10.1126/science.1230161 Ernst 2013 DMS Ubiquitin Phage Binding site-directed mutagenesis with doped oligos ELISA No No
@@ -60,7 +60,7 @@ PMID DOI First author Year Type Molecule Model Selection Type Mutagenesis Type S
606025657251 10.1126/science.1257360 Podgornaia 2015 DMS PhoQ Bacteria FACS NNS PCR Illumina No No
616125723163 10.1016/j.cell.2015.01.035 Stiffler 2016 DMS TEM1 B-lactamase E.coli Growth NNS PCR Illumina No XLS
626225823446 10.1534/genetics.115.175802 Starita 2015 DMS BRCA1 Yeast, Phage Growth, Binding microarray synthesis Illumina (barcoded and subassembly) No XLS
63- 25875337 10.1371/journal.pgen.1005147 Shalem 2015 MPRA 3’ UTR Yeast Fluorescence, Transcription microarray synthesis Illumina No XLS
63+ 25875337 10.1371/journal.pgen.1005147 Shalem 2015 MPRA 3’ UTR Yeast Fluorescence, Transcription microarray synthesis Illumina No XLS
646426040002 10.1073/pnas.1422285112 Romero 2015 DMS Bgl2 Bacteria/microfluidic droplets Activity error-prone PCR Illumina No No
656526132554 10.1371/journal.pgen.1005310 Wu 2015 DMS Polymerase PA Influenza Growth error-prone PCR Illumina PRJNA254185 XLS
666626170332 10.1073/pnas.1511328112 Kretz 2015 DMS VWF Phage Binding/cleavage doped oligo synthesis Illumina No XLS
@@ -161,7 +161,7 @@ PMID DOI First author Year Type Molecule Model Selection Type Mutagenesis Type S
16116130778069 10.1038/s41467-019-08777-y Michaels 2019 MPRA microRNA HEK293T polysome profiling degenerate oligos Illumina PRJNA516224 No
16216230936490 10.1038/s41564-019-0412-y Noda-Garcia 2019 DMS GDH Bacteria Growth NNS PCR Illumina No XLS
16316330956043 10.1016/j.molcel.2019.02.003 Ahler 2019 DMS Src Yeast Growth NNK PCR Illumina (barcoded and subassembly) GSE114098 XLS
164- 31267113 10.1038/s41587-019-0164-5 Sample 2019 MPRA 5’ UTR human cells polysome profiling random bases Illumina GSE114002 No
164+ 31267113 10.1038/s41587-019-0164-5 Sample 2019 MPRA 5’ UTR human cells polysome profiling random bases Illumina GSE114002 No
16516531395865 10.1038/s41467-019-11526-w Kircher 2019 MPRA Multiple mammalian promoters and enhancers multiple cell lines Transcription error-prone PCR Illumina GSE126550 TXT
16616631697803 10.1182/blood.2019002561 Bridgford 2020 DMS MPL Ba/F3 cells Growth NNN PCR Illlumina SRR10193506 TXT
16716732385156 10.1073/pnas.1918680117 Mehlhoff 2020 DMS TEM-1 BL E.coli Growth NNN PCR Illlumina PRJNA565437 XLS
0 commit comments