v2025.5.2

What's Changed

• Fixes undefined query parameter value when clicking on segments of St… by @davereinhart in #579
• fix: remove trailing period from toolbar preview site link by @bencap in #580
• fix: decimals were unsupported in calibration editor component range entries by @bencap in #584

Full Changelog: v2025.5.1...v2025.5.2

v2025.5.1

What's Changed

• Replace Alphafold URL HEAD request with check of PDBe Molstar viewer … by @davereinhart in #574

Full Changelog: v2025.5.0...v2025.5.1

v2025.5.0

What's Changed

• feat: ProteinStructureView: dynamic AlphaFold model file version by @davereinhart in #525
• feat: Add MaveMd search options for ClinGen Allele IDs, dbSNP rs IDs, and ClinVar Variation IDs by @davereinhart in #530
• feat: Show two different defaults histograms. by @EstelleDa in #541
• feat: Score set search result optimization by @jstone-dev in #493
• feat: Set includeExperimentScoreSetUrnsAndCount search param on search page by @davereinhart in #528
• fixed: Bins intersecting with only the boundary of a classification implied a range by @bencap in #524
• fixed: removing primary publication from publications list would freeze primary selection drop down by @bencap in #523
• feat: Add message for missing OddsPath calculations, update AccordionTab header by @bencap in #522
• feat: Include score and counts column metadata fields on ScoreSetCreator and ScoreSetEditor components by @davereinhart in #540
• feat: Add downloading multiple data options function by @EstelleDa in #519
• feat: Score calibration management for new model by @bencap in #529
• feat: Enhance authentication flow with redirect handling and path sanitization by @bencap in #559
• feat: UI Tweaks for VA-Spec Streaming Endpoints by @bencap in #565
• chore: update generated OpenAPI schema refs by @bencap in #567
• feat: Unified Calibration Table, Variant Search Calibration Column by @bencap in #561

Full Changelog: v2025.4.5...v2025.5.0

v2025.4.5

What's Changed

• Correct the url of downloading scores file. by @EstelleDa in #527
• Not showing the hgvs_pro column title if no count data by @EstelleDa in #521

Full Changelog: v2025.4.4...v2025.4.5

v2025.4.4

What's Changed

• Update AlphaFold model URL to version 6 in ProteinStructureView component by @bencap in #508
• Standardize spelling of OddsPath as one word. by @jstone-dev in #510

Full Changelog: v2025.4.3...v2025.4.4

v2025.4.3

What's Changed

• fixed: variable name in hgvs search for amino acid alleles was undefined by @bencap in #503
• Add meta-analyzed by field to score set metadata, enhance view w/ additional colons by @bencap in #505

Full Changelog: v2025.4.2...v2025.4.3

v2025.4.2

What's Changed

• Overlapping Histogram Labels by @bencap in #492
• ClinVar-style HGVS search by @jstone-dev in #496

Full Changelog: v2025.4.1...v2025.4.2

v2025.4.1

What's Changed

• Choice of dna or protein heatmap by @jstone-dev in #465
• Clinical UI improvements by @jstone-dev in #471
• Support for title/research only Score Calibrations by @bencap in #473
• Heatmap refactoring, fixes, and new coloring method by @jstone-dev in #475
• Histogram Options for Variants Based On Protein Effect by @bencap in #476
• Histogram options for variants based on protein effect by @jstone-dev in #481
• Variant search page content by @jstone-dev in #483
• Add Molecular Mechanism section to Assay Fact Sheet by @bencap in #486
• Title improvements by @jstone-dev in #485
• Histogram Color Palette Cleanup by @bencap in #490
• More paper changes by @jstone-dev in #489
• Standalone baseline score by @bencap in #495
• About Page by @bencap in #494

Full Changelog: v2025.4.0...v2025.4.1

v2025.4.0

New features and enhancements

• Display score ranges sorted by score (not by classification or evidence strength).
• Special calibration name handling for investigator-provided classes and Zeiberg ranges
• Use investigator-supplied functional class ranges to determine histogram colors
• Updates to heatmap, scoreset view, and protein visualization to include hydrophobicity and chemical classification for amino acids.
• Tentative rules (with exceptions) for splicing and NMD variant detection
• MaveMD search page edits
• Hide start- and stop-loss variants from the heatmap in clinical mode for non-endogenously-edited targets.
• Stop showing black heatmap cells for explicit NaN scores; treat them like other missing data
• Help & support screen updates
• Format improvements

Maintenance

• Stronger ESLint code linting rules and code formatting using Prettier
• Code cleanup, linting, and formatting
• Refactoring of some large Vue components

Bug fixes

• Fixed: Loading the counts preview table sometimes throws an error.
• Fixed: Heatmap does not appear for some score sets when in raw data mode.
• Fixed: WT AA variants translated from NT variants are offset when the variants do not begin at AA position 1
• Fixed: Editing a score set may fail without explanation.
• Fixed: Some synonymous variants are not displayed on the heatmap.
• Fixed: Calibration score range display overflows its container.

What's Changed

• Rename tax_id to code in Taxonomy by @EstelleDa in #443
• Correct Evidence Strength Signs and Color Pallette by @bencap in #445
• Merge release 2025.3.1 into 2025.4.0 by @jstone-dev in #448
• Merge release 2025.3.2 into 2025.4.0 by @jstone-dev in #449
• Clinical Control Histogram Improvements by @bencap in #427
• Controlled keywords - gene ontology by @EstelleDa in #362
• Clinical visualization features by @jstone-dev in #451
• Clinical UI improvements by @jstone-dev in #458
• Scoreset heatmap and protein visualization improvements and addition of hydrophobicity and chemical classes to Amino acids by @davereinhart in #459
• Add Help & Support Page with Dedicated Forum Linkouts by @bencap in #412
• Clinical UI improvements by @jstone-dev in #462
• Release 2025.3.2 by @jstone-dev in #463

Full Changelog: v2025.3.0...v2025.4.0

v2025.3.1

Highlights

New features

• Experiment metadata model changes
• Assay Facts sheet (visible when CLINICAL_FEATURES_ENABLED=true)
• Cache clinical controls to reduce wait times.
• Handle changes in ClinVar's vocabulary.
• Rename taxonomy's taxId as code.
• Clinical score set visualization features, including using mapped variant coordinates
• Ability to switch between raw and mapped/clinical views

Bug fixes

• The UI for switching clinical control versions was not shown when more than one version is available.
• Score range display is reversed.

What's Changed

• Rename tax_id to code in Taxonomy by @EstelleDa in #443
• Correct Evidence Strength Signs and Color Pallette by @bencap in #445
• Merge release 2025.3.1 into 2025.4.0 by @jstone-dev in #448
• Merge release 2025.3.2 into 2025.4.0 by @jstone-dev in #449
• Clinical Control Histogram Improvements by @bencap in #427
• Controlled keywords - gene ontology by @EstelleDa in #362
• Clinical visualization features by @jstone-dev in #451
• Release 2025.3.1 by @jstone-dev in #455

Full Changelog: v2025.3.0...v2025.3.1