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chrwiseSignatures to analyze signature interactions

The package provides several functions to calculate mutational signature interaction metrics.

  • cor_coda - pearson correlations based on compositional data analysis
  • cooccurrence - co-occurrence or mutual exclusivity based on Fisher's exact test
  • bcmi - Bias-corrected Mutual Information from mpmi package
  • cor_sigs - Spearman or Pearson correlations

The package also provides a function to produce summary interaction networks based on calculated interaction metrics.

Check the documentation of function plot_interaction_networks to see how plotting works.

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