gbmi_twas

TWAS scripts for Global Biobank Meta-analysis Initiative

The Scripts folder contains the following:

• DePMA_shell.R and MeTWAS_shell.R that provide sample code to run MOSTWAS models. Refer to Bhattacharya et al 2021 for more details.
• full_ancestry_FUSION.R and cross_ancestry_FUSION.R provides code to train models to compare ancestry-specific model performance in other ancestry groups.
• run_sumStats_wholeBlood.R gives sample code to run TWAS disease mapping.
• focus_finemapping.R and FOCUS_functions.R gives an approximate R implementation for FOCUS finemapping. Refer to Mancuso et al 2019 for more details.