This repository contains the analysis pipeline and tools used in McAllester & Pool 2025 to study inversion polymorphisms in Drosophila melanogaster. The code handles:
- Read alignment and quality control
- Inversion frequency calling
- Statistical analysis of frequency data
The SAIsim simulator used in this study is housed in a separate repository at https://github.com/csmcal/SAIsim.
analysis/: Main analysis scripts and pipelinesAlignment/: Read alignment and processing toolsSignificance/: Statistical analysis scriptsGraphing/: Data plotting scripts
If you have any reason to reference this repository, please cite:
McAllester, C. S., & Pool, J. E. (2025). The potential of inversions to accumulate balanced sexual antagonism is supported by simulations and Drosophila experiments. eLife.
This project is licensed under the MIT License - see the LICENSE file for details.