This repository contains code and data supporting the publication:

SATB1 is a subset-specific regulator of JAK-STAT signaling and cellular effector functions in human Treg and CD4 effector T cells

Authors: Saskia Kolb, Elizabeth D. Lochert, Leonie Diekmann, Linda Warmuth, Julia Ritter, Michael Weber, Markus Hoffmann, Markus List, Daniel Kotlarz, Dirk H. Busch, Christian Schmidl, Kathrin Schumann*
(*Corresponding author)

Repository Structure

• 📂 data/: Processed datasets used for data analysis
• 📂 lib/: Scripts for data analysis
• 📂 results/: Results from data analyses

Getting Started

Requirements

• Python (≥ 3.8)
• R (≥ 4.0)
• Python packages (listed in requirements.txt)
• R packages (listed in install_packages.R)

Installation

Clone the repository:

git clone https://github.com/daisybio/teff-treg-satb1-analysis.git
cd teff-treg-satb1-analysis

Install dependencies:

pip install -r requirements.txt 
Rscript install_packages.R

Running the Analysis

To reproduce the analyses, run the scripts located in the lib/ directory using the datasets in data/. Processed results can be found in results/.