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feat: Add 139 scientific skills from K-Dense-AI/claude-scientific-skills
Added comprehensive scientific skills collection covering: - 54+ Python packages (biopython, rdkit, scanpy, pytorch-lightning, scikit-learn, qiskit, etc.) - 26+ scientific databases (PubMed, ChEMBL, UniProt, COSMIC, ClinicalTrials.gov, etc.) - 20+ analysis & communication tools (literature-review, scientific-writing, peer-review, etc.) - 15+ scientific integrations (Benchling, DNAnexus, LatchBio, OMERO, Protocols.io, etc.) - Laboratory automation and specialized tools Source: https://github.com/K-Dense-AI/claude-scientific-skills License: MIT License Copyright: © 2025 K-Dense Inc. Updated README.md with comprehensive attribution section including: - K-Dense-AI/claude-scientific-skills - Official Anthropic sources (skills, claude-code) - Community contributions (obra/superpowers, alirezarezvani/claude-skills, wshobson/agents) - NerdyChefsAI Skills - awesome-claude-code and awesome-claude-skills Total skills: 105 → 244 (+139 scientific skills) Updated components.json catalog and security-report.json 🤖 Generated with Claude Code (https://claude.com/claude-code) Co-Authored-By: Claude Sonnet 4.5 <noreply@anthropic.com>
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README.md

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This collection includes components from multiple sources:
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**Agents Collection:**
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- **wshobson/agents Collection** by [wshobson](https://github.com/wshobson/agents) - Licensed under MIT License (48 agents)
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**Commands Collection:**
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- **awesome-claude-code Commands** by [hesreallyhim](https://github.com/hesreallyhim/awesome-claude-code) - Licensed under CC0 1.0 Universal (21 commands)
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Some of the commands and resources included in this marketplace come from open-source community repositories originally listed in [awesome-claude-code](https://github.com/hesreallyhim/awesome-claude-code).
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Each of these resources retains its **original license and attribution**, as defined by their respective authors (mostly MIT-licensed).
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Please note that **awesome-claude-code** is **no longer licensed under CC 1.0**.
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**Scientific Skills:**
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- **[K-Dense-AI/claude-scientific-skills](https://github.com/K-Dense-AI/claude-scientific-skills)** by K-Dense Inc. - MIT License (139 scientific skills for biology, chemistry, medicine, and computational research)
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**Official Anthropic:**
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- **[anthropics/skills](https://github.com/anthropics/skills)** - Official Anthropic skills (21 skills)
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- **[anthropics/claude-code](https://github.com/anthropics/claude-code)** - Development guides and examples (10 skills)
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**Community Skills & Agents:**
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- **[obra/superpowers](https://github.com/obra/superpowers)** by Jesse Obra - MIT License (14 workflow skills)
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- **[alirezarezvani/claude-skills](https://github.com/alirezarezvani/claude-skills)** by Alireza Rezvani - MIT License (36 professional role skills)
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- **[wshobson/agents](https://github.com/wshobson/agents)** by wshobson - MIT License (48 agents)
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- **NerdyChefsAI Skills** - Community contribution - MIT License (specialized enterprise skills)
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**Commands & Tools:**
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- **[awesome-claude-code](https://github.com/hesreallyhim/awesome-claude-code)** by hesreallyhim - CC0 1.0 Universal (21 commands)
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- **[awesome-claude-skills](https://github.com/mehdi-lamrani/awesome-claude-skills)** - Apache 2.0 (community skills)
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- **move-code-quality-skill** - MIT License
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- **cocoindex-claude** - Apache 2.0
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Each of these resources retains its **original license and attribution**, as defined by their respective authors.
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We respect and credit all original creators for their work and contributions to the Claude ecosystem.
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## 📄 License
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---
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name: adaptyv
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description: Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
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---
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# Adaptyv
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Adaptyv is a cloud laboratory platform that provides automated protein testing and validation services. Submit protein sequences via API or web interface and receive experimental results in approximately 21 days.
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## Quick Start
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### Authentication Setup
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Adaptyv requires API authentication. Set up your credentials:
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1. Contact support@adaptyvbio.com to request API access (platform is in alpha/beta)
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2. Receive your API access token
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3. Set environment variable:
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```bash
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export ADAPTYV_API_KEY="your_api_key_here"
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```
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Or create a `.env` file:
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```
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ADAPTYV_API_KEY=your_api_key_here
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```
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### Installation
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Install the required package using uv:
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```bash
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uv pip install requests python-dotenv
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```
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### Basic Usage
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Submit protein sequences for testing:
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```python
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import os
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import requests
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from dotenv import load_dotenv
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load_dotenv()
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api_key = os.getenv("ADAPTYV_API_KEY")
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base_url = "https://kq5jp7qj7wdqklhsxmovkzn4l40obksv.lambda-url.eu-central-1.on.aws"
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headers = {
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"Authorization": f"Bearer {api_key}",
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"Content-Type": "application/json"
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}
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# Submit experiment
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response = requests.post(
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f"{base_url}/experiments",
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headers=headers,
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json={
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"sequences": ">protein1\nMKVLWALLGLLGAA...",
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"experiment_type": "binding",
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"webhook_url": "https://your-webhook.com/callback"
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}
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)
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experiment_id = response.json()["experiment_id"]
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```
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## Available Experiment Types
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Adaptyv supports multiple assay types:
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- **Binding assays** - Test protein-target interactions using biolayer interferometry
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- **Expression testing** - Measure protein expression levels
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- **Thermostability** - Characterize protein thermal stability
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- **Enzyme activity** - Assess enzymatic function
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See `reference/experiments.md` for detailed information on each experiment type and workflows.
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## Protein Sequence Optimization
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Before submitting sequences, optimize them for better expression and stability:
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**Common issues to address:**
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- Unpaired cysteines that create unwanted disulfides
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- Excessive hydrophobic regions causing aggregation
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- Poor solubility predictions
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**Recommended tools:**
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- NetSolP / SoluProt - Initial solubility filtering
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- SolubleMPNN - Sequence redesign for improved solubility
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- ESM - Sequence likelihood scoring
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- ipTM - Interface stability assessment
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- pSAE - Hydrophobic exposure quantification
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See `reference/protein_optimization.md` for detailed optimization workflows and tool usage.
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## API Reference
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For complete API documentation including all endpoints, request/response formats, and authentication details, see `reference/api_reference.md`.
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## Examples
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For concrete code examples covering common use cases (experiment submission, status tracking, result retrieval, batch processing), see `reference/examples.md`.
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## Important Notes
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- Platform is currently in alpha/beta phase with features subject to change
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- Not all platform features are available via API yet
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- Results typically delivered in ~21 days
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- Contact support@adaptyvbio.com for access requests or questions
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- Suitable for high-throughput AI-driven protein design workflows

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