@@ -163,6 +163,44 @@ in our **Advanced User Guide**.
163163
164164## HDF5 (e.g. Single Cell)
165165
166+ !!! info "Limitations"
167+ HDF5 is supported as Attached File in ODM with ability to observe and search by File Structure (Contents) only.
168+ We are working on full functionality for HDF5 data content parsing, search, and filtering.
169+
170+ ** HDF5 (Hierarchical Data Format version 5)** is a widely used data format in genomic research, particularly in
171+ Single Cell studies. It is designed to store large, complex datasets efficiently, making it a preferred choice for
172+ structured biological data such as gene expression matrices and metadata.
173+
174+ The ODM now supports HDF5 file upload as Attached File, search by File Structure (Contents), and manage these
175+ files within Studies.
176+
177+ ### Supported HDF5 Formats
178+
179+ - ** .h5, .h5ad** - Standard HDF5 files
180+ - ** .h5.gz, .h5ad.zip** - Compressed versions of standard HDF5 files
181+
182+ ### Viewing File Structure (Contents)
183+
184+ - ** Access File Contents via GUI** : The ODM displays File Contents on the Data Tab of Metadata Editor. It is
185+ accessible on ` Contents ` button click.
186+ - ** Retrieve File Contents via API** : You can retrieve File Contents for the list of files or by unique
187+ Genestack Accession.
188+
189+ ### Searching HDF5 Files by File Contents
190+
191+ Users can search via GUI and API for:
192+
193+ - ** Unique File** : by Genestack Accession.
194+ - ** Files** :
195+
196+ - By File Contents fields/pathways.
197+ - By Study Genestack Accession.
198+
199+ - ** Studies** :
200+
201+ - By File Contents fields/pathways.
202+ - By File Genestack Accession.
203+
166204For a detailed description and instructions on using HDF5, visit the ** [ Supported Data Formats page] ( ../doc-odm-user-guide/supported-formats.md ) **
167205in our ** Advanced User Guide** .
168206
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