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Data generation and analysis of the coupled decision-making of the EMT and metabolism networks. This work is available as a preprint at https://www.biorxiv.org/content/10.1101/2022.08.02.502548v1

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EMT_MR

Decoding the coupled decision-making of the epithelial-mesenchymal transition and metabolic reprogramming in cancer

This work is available as a preprint https://www.biorxiv.org/content/10.1101/2022.08.02.502548v1

Data Generation

  • For the tristable networks, the code for generating is in coupledWReg_Ccode

  • For the PSF networks, the code is listed under coupledWReg_Ccode/PSF

  • For the cells without hybrid states, the code is listed under normalCells_coupled

Analysis (crosstalk/analysis)

  • print_data.py

  • aux_func_States.py

  • functions_for_plotting.py

  • reduced_uh.py

  • find_upregs.py prints the information of which parameters (and files) result in upregulated, downregulated, etc expression of the coupled E/M-W/O state

Figures for SI and main text

They are listed in the draft folder, will need to utilize the data generated from the analysis folder

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Data generation and analysis of the coupled decision-making of the EMT and metabolism networks. This work is available as a preprint at https://www.biorxiv.org/content/10.1101/2022.08.02.502548v1

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