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Glimepiride Web Application "Digital Twin"

This repository contains the code of the digital twin web application of glimepiride available at https://glimepiride.de.

Webapp Screenshot

The model repository is available from https://github.com/matthiaskoenig/glimepiride-model.git.

Run with docker

# Build the image
docker build -t glimepiride_app .

# Start the container, mapping port 8080
docker run -p 4567:8080 -it glimepiride_app

The app is available from http://localhost:4567

Run locally

Use uv to setup the dependencies

uv venv
uv sync

To run the app locally use

marimo run src/app.py 

To modify the app use

marimo edit src/app.py

License

This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.

Funding

Matthias König was supported by the Federal Ministry of Education and Research (BMBF, Germany) within LiSyM by grant number 031L0054 and ATLAS by grant number 031L0304B and by the German Research Foundation (DFG) within the Research Unit Program FOR 5151 QuaLiPerF (Quantifying Liver Perfusion-Function Relationship in Complex Resection - A Systems Medicine Approach) by grant number 436883643 and by grant number 465194077 (Priority Programme SPP 2311, Subproject SimLivA). This work was supported by the BMBF-funded de.NBI Cloud within the German Network for Bioinformatics Infrastructure (de.NBI) (031A537B, 031A533A, 031A538A, 031A533B, 031A535A, 031A537C, 031A534A, 031A532B).

© 2024-2025 Michelle Elias & Matthias König, Systems Medicine of the Liver

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